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Protein
Submitted name:

Cytochrome c oxidase subunit II

Gene

COX2

Organism
Onchocerca volvulus
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

Biological processElectron transportSAAS annotation, Transport
LigandCopperSAAS annotation, Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome c oxidase subunit IIImported
Submitted name:
Cytochrome oxidase subunit 2Imported
Gene namesi
Name:COX2Imported
Encoded oniMitochondrionImported
OrganismiOnchocerca volvulusImported
Taxonomic identifieri6282 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaSpiruridaSpiruromorphaFilarioideaOnchocercidaeOnchocerca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 47HelicalSequence analysisAdd BLAST19
Transmembranei67 – 86HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane, MitochondrionImported

Structurei

3D structure databases

ProteinModelPortaliO47580
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini95 – 228COX2_CUAInterPro annotationAdd BLAST134

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

CDDicd13912 CcO_II_C, 1 hit
Gene3Di1.10.287.90, 1 hit
2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR002429 CcO_II-like_C
IPR034210 CcO_II_C
IPR001505 Copper_CuA
IPR008972 Cupredoxin
IPR036257 Cyt_c_oxidase_su2_TM_sf
PfamiView protein in Pfam
PF00116 COX2, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
PROSITEiView protein in PROSITE
PS00078 COX2, 1 hit
PS50857 COX2_CUA, 1 hit

Sequencei

Sequence statusi: Complete.

O47580-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLQNYVFPI PGNSYVFCCY YIHNYYSHII FFGFFVMFLV SGGIYFFGNS
60 70 80 90 100
FKFNLKRSDS RMIELILQVL IVNFLIMMAG PGFWLIQYQG RMFRQSELTL
110 120 130 140 150
KVIGHQWYWS YEYGDSGKLC FDSFMKSLDD LSLGDFRLFD VDNRCVLPVG
160 170 180 190 200
VNVGVYCTSS DVIHSFAIPK CFIKMDALNG LLTKVTCSFS CSGLFFGQCS
210 220 230
EICGANHSFM PIVLELTSLE CWKGWSVNYL LG
Length:232
Mass (Da):26,689
Last modified:June 1, 1998 - v1
Checksum:i0651064D1509482D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF015193 Genomic DNA Translation: AAC61619.1
KT599912 Genomic DNA Translation: ALG63681.1
PIRiT11072
RefSeqiNP_008377.1, NC_001861.1

Genome annotation databases

GeneIDi808138

Similar proteinsi

Entry informationi

Entry nameiO47580_ONCVO
AccessioniPrimary (citable) accession number: O47580
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health