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O47491

- COX3_METSE

UniProt

O47491 - COX3_METSE

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Protein
Cytochrome c oxidase subunit 3
Gene
COIII
Organism
Metridium senile (Brown sea anemone) (Frilled sea anemone)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiMetridium senile (Brown sea anemone) (Frilled sea anemone)
Taxonomic identifieri6116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaNynantheaeMetridiidaeMetridium

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei16 – 3621Helical; Reviewed prediction
Add
BLAST
Transmembranei39 – 5921Helical; Reviewed prediction
Add
BLAST
Transmembranei83 – 10321Helical; Reviewed prediction
Add
BLAST
Transmembranei128 – 14821Helical; Reviewed prediction
Add
BLAST
Transmembranei160 – 18021Helical; Reviewed prediction
Add
BLAST
Transmembranei198 – 21821Helical; Reviewed prediction
Add
BLAST
Transmembranei241 – 26121Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 262262Cytochrome c oxidase subunit 3
PRO_0000183808Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO47491.
SMRiO47491. Positions 7-262.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O47491-1 [UniParc]FASTAAdd to Basket

« Hide

MKSTVYHPYH LVDPSPWPYV GACGALFITV GSVVYFHYSQ TWVLLMGAIT    50
LSLTMIVWWR DVIREATFQG LHTMVVKQGL KYGMLLFILS EVLFFFSFFW 100
AFFHSSIAPN IELGAVWPPQ GINPLNPFSV PLLNTAVLLS SGATVTWAHH 150
ALISGKKTEA INGLTITVVL GLIFTGLQAM EYYEAPFAIS DSVYGSTFFV 200
ATGFHGMHVI IGTTFLAVCL ARLVYHQFTR HHHLGFEAAS WYWHFVDVVW 250
LFLYICIYWW GS 262
Length:262
Mass (Da):29,631
Last modified:June 1, 1998 - v1
Checksum:i15EC3F1270D3C819
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF000023 Genomic DNA. Translation: AAC04629.1.
PIRiT11883.
RefSeqiNP_009252.1. NC_000933.1.

Genome annotation databases

GeneIDi808768.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF000023 Genomic DNA. Translation: AAC04629.1 .
PIRi T11883.
RefSeqi NP_009252.1. NC_000933.1.

3D structure databases

ProteinModelPortali O47491.
SMRi O47491. Positions 7-262.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 808768.

Organism-specific databases

CTDi 4514.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Beagley C.T., Okimoto R., Wolstenholme D.R.
    Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: White morph.

Entry informationi

Entry nameiCOX3_METSE
AccessioniPrimary (citable) accession number: O47491
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 1, 1998
Last modified: September 3, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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