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O47491 (COX3_METSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismMetridium senile (Brown sea anemone) (Frilled sea anemone)
Taxonomic identifier6116 [NCBI]
Taxonomic lineageEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaNynantheaeMetridiidaeMetridium

Protein attributes

Sequence length262 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 262262Cytochrome c oxidase subunit 3
PRO_0000183808

Regions

Transmembrane16 – 3621Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane83 – 10321Helical; Potential
Transmembrane128 – 14821Helical; Potential
Transmembrane160 – 18021Helical; Potential
Transmembrane198 – 21821Helical; Potential
Transmembrane241 – 26121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O47491 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 15EC3F1270D3C819

FASTA26229,631
        10         20         30         40         50         60 
MKSTVYHPYH LVDPSPWPYV GACGALFITV GSVVYFHYSQ TWVLLMGAIT LSLTMIVWWR 

        70         80         90        100        110        120 
DVIREATFQG LHTMVVKQGL KYGMLLFILS EVLFFFSFFW AFFHSSIAPN IELGAVWPPQ 

       130        140        150        160        170        180 
GINPLNPFSV PLLNTAVLLS SGATVTWAHH ALISGKKTEA INGLTITVVL GLIFTGLQAM 

       190        200        210        220        230        240 
EYYEAPFAIS DSVYGSTFFV ATGFHGMHVI IGTTFLAVCL ARLVYHQFTR HHHLGFEAAS 

       250        260 
WYWHFVDVVW LFLYICIYWW GS 

« Hide

References

[1]Beagley C.T., Okimoto R., Wolstenholme D.R.
Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: White morph.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF000023 Genomic DNA. Translation: AAC04629.1.
PIRT11883.
RefSeqNP_009252.1. NC_000933.1.

3D structure databases

ProteinModelPortalO47491.
SMRO47491. Positions 7-262.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID808768.

Organism-specific databases

CTD4514.

Phylogenomic databases

ProtClustDBMTH00024.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_METSE
AccessionPrimary (citable) accession number: O47491
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 1, 1998
Last modified: April 16, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families