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O47475

- COX3_HETBL

UniProt

O47475 - COX3_HETBL

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Protein

Cytochrome c oxidase subunit 3

Gene

COIII

Organism
Heterololigo bleekeri (Spear squid) (Loligo bleekeri)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiHeterololigo bleekeri (Spear squid) (Loligo bleekeri)
Taxonomic identifieri1423826 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaCephalopodaColeoideaNeocoleoideaDecapodiformesTeuthidaMyopsinaLoliginidaeHeterololigo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321HelicalSequence AnalysisAdd
BLAST
Transmembranei36 – 5621HelicalSequence AnalysisAdd
BLAST
Transmembranei80 – 10021HelicalSequence AnalysisAdd
BLAST
Transmembranei125 – 14521HelicalSequence AnalysisAdd
BLAST
Transmembranei154 – 17421HelicalSequence AnalysisAdd
BLAST
Transmembranei195 – 21521HelicalSequence AnalysisAdd
BLAST
Transmembranei237 – 25721HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 259259Cytochrome c oxidase subunit 3PRO_0000183801Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO47475.
SMRiO47475. Positions 6-259.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O47475-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIRNPFHLVE YSPWPLTGSL GAMFLTVGLT SWFHNHGFIT MLLGLFLVLM
60 70 80 90 100
TMFQWWRDII RESTFQGYHT MKVSLGMRMG MVLFITSEIC FFFAFFWAYF
110 120 130 140 150
HSSLAPNTDI GASWPPLHIN PLNPFQIPLL NTAILLASGV TVTWAHHSLM
160 170 180 190 200
GGNHAEATQS MVLTVILGGY FTLLQAEEYM EAPFSIADSV YGATFFVATG
210 220 230 240 250
FHGLHVIIGS VFLLICLFRM LIHHFSTNHH FGFEAAAWYW HFVDVVWLIL

YTCIYWWGS
Length:259
Mass (Da):29,637
Last modified:June 1, 1998 - v1
Checksum:i10B61CB81E5ACA41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB009838 Genomic DNA. Translation: BAA24058.1.
AB029616 Genomic DNA. Translation: BAB03645.1.
RefSeqiNP_062833.1. NC_002507.1.

Genome annotation databases

GeneIDi809435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB009838 Genomic DNA. Translation: BAA24058.1 .
AB029616 Genomic DNA. Translation: BAB03645.1 .
RefSeqi NP_062833.1. NC_002507.1.

3D structure databases

ProteinModelPortali O47475.
SMRi O47475. Positions 6-259.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 809435.

Organism-specific databases

CTDi 4514.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Completing of squid (Loligo breekeri) mitochondrial genome sequencing."
    Tomita K., Ueda T., Watanabe K.
    Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiCOX3_HETBL
AccessioniPrimary (citable) accession number: O47475
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: June 1, 1998
Last modified: October 29, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3