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O47475 (COX3_HETBL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismHeterololigo bleekeri (Spear squid) (Loligo bleekeri)
Taxonomic identifier1423826 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaMolluscaCephalopodaColeoideaNeocoleoideaDecapodiformesTeuthidaMyopsinaLoliginidaeHeterololigo

Protein attributes

Sequence length259 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 259259Cytochrome c oxidase subunit 3
PRO_0000183801

Regions

Transmembrane13 – 3321Helical; Potential
Transmembrane36 – 5621Helical; Potential
Transmembrane80 – 10021Helical; Potential
Transmembrane125 – 14521Helical; Potential
Transmembrane154 – 17421Helical; Potential
Transmembrane195 – 21521Helical; Potential
Transmembrane237 – 25721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O47475 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 10B61CB81E5ACA41

FASTA25929,637
        10         20         30         40         50         60 
MIRNPFHLVE YSPWPLTGSL GAMFLTVGLT SWFHNHGFIT MLLGLFLVLM TMFQWWRDII 

        70         80         90        100        110        120 
RESTFQGYHT MKVSLGMRMG MVLFITSEIC FFFAFFWAYF HSSLAPNTDI GASWPPLHIN 

       130        140        150        160        170        180 
PLNPFQIPLL NTAILLASGV TVTWAHHSLM GGNHAEATQS MVLTVILGGY FTLLQAEEYM 

       190        200        210        220        230        240 
EAPFSIADSV YGATFFVATG FHGLHVIIGS VFLLICLFRM LIHHFSTNHH FGFEAAAWYW 

       250 
HFVDVVWLIL YTCIYWWGS 

« Hide

References

[1]"Completing of squid (Loligo breekeri) mitochondrial genome sequencing."
Tomita K., Ueda T., Watanabe K.
Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB009838 Genomic DNA. Translation: BAA24058.1.
AB029616 Genomic DNA. Translation: BAB03645.1.
RefSeqNP_062833.1. NC_002507.1.

3D structure databases

ProteinModelPortalO47475.
SMRO47475. Positions 6-259.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID809435.

Organism-specific databases

CTD4514.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_HETBL
AccessionPrimary (citable) accession number: O47475
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: June 1, 1998
Last modified: June 11, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families