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Protein
Submitted name:

MHC class I alpha chain 2

Gene

B-FIV

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • peptide antigen binding Source: AgBase

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I alpha chain 2Imported
Submitted name:
MHC class I glycoproteinImported
Submitted name:
MHC class I moleculeImported
Gene namesi
Name:B-FIVImported
Synonyms:BF2Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei298 – 323HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501013290722 – 355Sequence analysisAdd BLAST334

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi120 ↔ 182Combined sources
Disulfide bondi220 ↔ 276Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4E0RX-ray2.26A/D22-291[»]
4G42X-ray2.29A/D22-291[»]
4G43X-ray1.80A/D22-291[»]
SMRiO46790.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini203 – 282Ig-likeInterPro annotationAdd BLAST80

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410II5V. Eukaryota.
ENOG4111K8F. LUCA.
HOVERGENiHBG016709.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
PRINTSiPR01638. MHCCLASSI.
SMARTiView protein in SMART
SM00407. IGc1. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Complete.

O46790-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPCGALGLG LLLAAVCGAA AELHTLRYIR TAMTDPGPGQ PWFVTVGYVD
60 70 80 90 100
GELFVHYNST ARRYVPRTEW IAANTDQQYW DGQTQIGQLN EQINRENLGI
110 120 130 140 150
RQRRYNQTGG SHTVQWMFGC DILEDGTIRG YRQSAYDGRD FIALDKDMKT
160 170 180 190 200
FTAAVPEAVP TKRKWEEESE PERWKNYLEE TCVEWLRRYV EYGKAELGRR
210 220 230 240 250
ERPEVRVWGK EADGILTLSC RAHGFYPRPI VVSWLKDGAV RGQDAHSGGI
260 270 280 290 300
VPNGDGTYHT WVTIDAQPGD GDKYQCRVEH ASLPQPGLYS WEPPQPNLVP
310 320 330 340 350
IVAGVAVAIV AIAIVVGVGF IIYRRHAGKK GKGYNIAPDR EGGSSSSSTG

SNPTI
Length:355
Mass (Da):39,398
Last modified:June 1, 1998 - v1
Checksum:i8B08E669AEF5AE37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF013494 mRNA. Translation: AAC17591.1.
AB426148 Genomic DNA. Translation: BAG69400.1.
AM282693 Genomic DNA. Translation: CAK54654.1.
AM282699 Genomic DNA. Translation: CAK54660.1.
UniGeneiGga.33600.
Gga.4973.

Similar proteinsi

Entry informationi

Entry nameiO46790_CHICK
AccessioniPrimary (citable) accession number: O46790
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: September 27, 2017
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources