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Protein
Submitted name:

Pregnancy-associated glycoprotein

Gene
N/A
Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei93PROSITE-ProRule annotation1
Active sitei276PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl proteasePROSITE-ProRule annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.051

Names & Taxonomyi

Protein namesi
Submitted name:
Pregnancy-associated glycoproteinImported
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501274566816 – 388Sequence analysisAdd BLAST373

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO46524
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 385Peptidase A1InterPro annotationAdd BLAST311

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili24 – 44Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1339 Eukaryota
ENOG410XNV7 LUCA
HOVERGENiHBG000482
KOiK06002

Family and domain databases

Gene3Di2.40.70.10, 2 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR001969 Aspartic_peptidase_AS
IPR012848 Aspartic_peptidase_N
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PfamiView protein in Pfam
PF07966 A1_Propeptide, 1 hit
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS00141 ASP_PROTEASE, 2 hits
PS51767 PEPTIDASE_A1, 1 hit

Sequencei

Sequence statusi: Complete.

O46524-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWLWVLGLV ALSECLVTIP LTRVKSMREN LREKDRLKDF LENHPYNLAY
60 70 80 90 100
KFVDSVNLDL GIYFEPMRNY LDLAYVGTIS IGTPPQEFKV IFDTGSSDLW
110 120 130 140 150
VPSIYCSSPA CANHNVFNPL RSSTFRISGR PIHLQYGSGT MSGFLAYDTV
160 170 180 190 200
RFGGLVDVAQ AFGLSLREPG KFMEYAVFDG ILGLAYPSLS LRGTVPVFDN
210 220 230 240 250
LWKQGLISQE LFAFYLSKKD EEGSVVMFGG VDHSYYSGDL NWVPVSKRLY
260 270 280 290 300
WQLSMDSISM NGEVIACDGG CQAIIDTGTS LLIGPSHVVF NIQMIIGANQ
310 320 330 340 350
SYSGEYVVDC DAANTLPDIV FTINGIDYPV PASAYIQEGP QGTCYSGFDE
360 370 380
SGDSLLVSDS WILGDVFLRL YFTVFDRENN RIGLALAV
Length:388
Mass (Da):43,030
Last modified:June 1, 1998 - v1
Checksum:i4DEA6D7590F9A92C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF036953 mRNA Translation: AAB91422.1
RefSeqiNP_001009868.1, NM_001009868.1

Genome annotation databases

GeneIDi493954
KEGGifca:493954

Similar proteinsi

Entry informationi

Entry nameiO46524_FELCA
AccessioniPrimary (citable) accession number: O46524
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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