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Protein
Submitted name:

Pregnancy-associated glycoprotein 12

Gene

PAG12

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei86PROSITE-ProRule annotation1
Active sitei267PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl proteasePROSITE-ProRule annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.094.

Names & Taxonomyi

Protein namesi
Submitted name:
Pregnancy-associated glycoprotein 12Imported
Gene namesi
Name:PAG12Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiO46500.

Structurei

3D structure databases

ProteinModelPortaliO46500.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini68 – 373Peptidase A1InterPro annotationAdd BLAST306

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1339. Eukaryota.
ENOG410XNV7. LUCA.
HOGENOMiHOG000197681.
HOVERGENiHBG000482.
KOiK06002.

Family and domain databases

Gene3Di2.40.70.10. 2 hits.
InterProiView protein in InterPro
IPR001461. Aspartic_peptidase_A1.
IPR001969. Aspartic_peptidase_AS.
IPR012848. Aspartic_peptidase_N.
IPR033121. PEPTIDASE_A1.
IPR021109. Peptidase_aspartic_dom.
PANTHERiPTHR13683. PTHR13683. 1 hit.
PfamiView protein in Pfam
PF07966. A1_Propeptide. 1 hit.
PF00026. Asp. 1 hit.
PRINTSiPR00792. PEPSIN.
SUPFAMiSSF50630. SSF50630. 1 hit.
PROSITEiView protein in PROSITE
PS00141. ASP_PROTEASE. 2 hits.
PS51767. PEPTIDASE_A1. 1 hit.

Sequencei

Sequence statusi: Complete.

O46500-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWLVLLGLV ALSECIVILP LRKMKTLRET LREKNLLNNF LEERAYRLSK
60 70 80 90 100
KDSKITIHPL KNYLDMAYVG NITIGTPPQE FRVVFDTGSA DLWVPSISCV
110 120 130 140 150
SPACYTHKTF NLHNSSSFGQ THQPISISYG PGIIQGFLGS DTVRIGNLVS
160 170 180 190 200
LKQSFGLSQE EYGFDGAPFD GVLGLAYPSI SIKGIIPIFD NLWSQGAFSE
210 220 230 240 250
PVFAFYLNTC QPEGSVVMFG GVDHRYYKGE LNWIPVSQTR YWQISMNRIS
260 270 280 290 300
MNGNVTACSR GCQALLDTGT SMIHGPTRLI TNIHKLMNAR HQGSEYVVSC
310 320 330 340 350
DAVKTLPPVI FNINGIDYPL PPQAYITKAQ NFCLSIFHGG TETSSPETWI
360 370
LGGVFLRQYF SVFDRRNDSI GLAQV
Length:375
Mass (Da):41,756
Last modified:June 1, 1998 - v1
Checksum:i96CCD89FF8CD670F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020514 mRNA. Translation: AAC04685.1.
RefSeqiNP_788795.1. NM_176622.1.
UniGeneiBt.15984.

Genome annotation databases

GeneIDi337906.
KEGGibta:337906.

Similar proteinsi

Entry informationi

Entry nameiO46500_BOVIN
AccessioniPrimary (citable) accession number: O46500
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: July 5, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation