O46498 (O46498_BOVIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Pregnancy-associated glycoprotein 10 EMBL AAC04683.2

Gene names

Name:

PAG10 EMBL AAC04683.2

Organism

Bos taurus (Bovine) EMBL AAC04683.2

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase A1 family. RuleBase RU000454

Ontologies

Keywords
Molecular function	Aspartyl protease RuleBase RU000454 SAAS SAAS012848 Hydrolase Protease
PTM	Disulfide bond SAAS SAAS012848
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	aspartic-type endopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O46498 [UniParc]. Last modified October 2, 2007. Version 2. Checksum: 50A5F6C13F1B4F4D	FASTA	381	42,586
	10 20 30 40 50 60 MKWLGLLGLV ALSECMVIIP LRQMKTMRET LRERHLLTNF SEEHPYNLSQ KAANDQNIIY 70 80 90 100 110 120 HHPLRSYKDF SYIGNINIGT PPQEFQVLFD TGSSSLWVPS IYCQSSSCYK HNSFVPCNSS 130 140 150 160 170 180 TFKATNKIFN TNYTATSIKG YLVYDTVRIG NLVSVAQPFG LSLKEFGFDD VPFDGILGLG 190 200 210 220 230 240 YPRRTITGAN PIFDNLWKQG VISEPVFAFY LSSQKENGSV VMFGGVNRAY YKGELNWVPV 250 260 270 280 290 300 SQVGSWHINI DSISMNGTVV ACKRGCQALL DTGTAFLRGP RGSVSKIQKL IHARPIDREH 310 320 330 340 350 360 VVSCQAIGTL PPAVFTINGI DYPVPAQAYI QSLSGYCFSN FLVRPQRVNE SETWILGEVF 370 380 LRLYFSVFDR GNNRIGLAPA V

References

[1]

"The diversity and evolutionary relationships of the pregnancy-associated glycoproteins, an aspartic proteinase subfamily consisting of many trophoblast-expressed genes." Xie S., Green J., Bixby J.B., Szafranska B., DeMartini J.C., Hecht S., Roberts R.M. Proc. Natl. Acad. Sci. U.S.A. 94:12809-12816(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL AAC04683.2.

[2]

Xie S., Green J., Roberts R.M. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL AAC04683.2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF020512 mRNA. Translation: AAC04683.2.
IPI	IPI00903921.
RefSeq	NP_788794.2. NM_176621.3.
UniGene	Bt.4115.
3D structure databases
ProteinModelPortal	O46498.
ModBase	Search...
Protein-protein interaction databases
STRING	9913.ENSBTAP00000008277.
Protein family/group databases
MEROPS	A01.971.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	337904.
KEGG	bta:337904.
Organism-specific databases
CTD	337904.
Phylogenomic databases
eggNOG	KOG1339.
HOGENOM	HOG000197681.
HOVERGEN	HBG000482.
KO	K06002.
OrthoDB	EOG46HG9X.
Family and domain databases
Gene3D	2.40.70.10. 2 hits.
InterPro	IPR001461. Peptidase_A1. IPR021109. Peptidase_aspartic. IPR001969. Peptidase_aspartic_AS. IPR012848. Propep_A1. [Graphical view]
PANTHER	PTHR13683. PTHR13683. 1 hit.
Pfam	PF07966. A1_Propeptide. 1 hit. PF00026. Asp. 1 hit. [Graphical view]
PRINTS	PR00792. PEPSIN.
SUPFAM	SSF50630. Pept_Aspartic. 1 hit.
PROSITE	PS00141. ASP_PROTEASE. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	20812466.

Entry information

Entry name

O46498_BOVIN

Accession

Primary (citable) accession number: O46498

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	October 2, 2007
Last modified:	April 3, 2013
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)