O46345 (O46345_LOLPE) Unreviewed, UniProtKB/TrEMBL
Last modified
October 19, 2011.
Version 60.
History...
Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Submitted name: S-syntaxin EMBL CAA74913.1 Submitted name: Syntaxin EMBL BAA24019.1 |
| Organism | Loligo pealeii (Longfin inshore squid) (Loligo pallida) EMBL CAA74913.1 |
| Taxonomic identifier | 1051067 [NCBI] |
| Taxonomic lineage | Eukaryota › Metazoa › Mollusca › Cephalopoda › Coleoidea › Neocoleoidea › Decapodiformes › Teuthida › Myopsina › Loliginidae › Doryteuthis |
Protein attributes
| Sequence length | 292 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Sequence similarities | Belongs to the syntaxin family. RuleBase RU003858 Contains 1 t-SNARE coiled-coil homology domain. SAAS SAAS000727 |
Ontologies
| Keywords | |
|---|---|
| Domain | Coiled coil SAAS SAAS000727 |
| Technical term | 3D-structure PDB 1S94 PDB 1L4A |
| Gene Ontology (GO) | |
| Biological process | intracellular protein transport Inferred from electronic annotation. Source: InterPro vesicle-mediated transportInferred from electronic annotation. Source: InterPro |
| Cellular component | membrane Inferred from electronic annotation. Source: InterPro |
| Molecular function | SNAP receptor activity Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequences
| ||||||||||||||||||
References
| [1] | "Presynaptic injection of syntaxin-specific antibodies blocks transmission in the squid giant synapse." Sugimori M., Tong C.-T., Fukuda M., Moreira J.E., Kojima T., Mikoshiba K., Llinas R. Neuroscience 86:39-51(1998) [PubMed: 9692742] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Optic lobe EMBL BAA24019.1. |
| [2] | "Crystal structure of the Habc domain of neuronal syntaxin from the squid Loligo pealei reveals conformational plasticity at its C-terminus." Bracher A., Weissenhorn W. BMC Struct. Biol. 4:6-6(2004) [PubMed: 15113421] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.34 ANGSTROMS) OF 2-175. |
| [3] | "Disruption of syntaxin-mediated protein interactions blocks neurotransmitter secretion." O'Connor V., Heuss C., De Bello W.M., Dresbach T., Charlton M.P., Hunt J.H., Pellegrini L.L., Hodel A., Burger M.M., Betz H., Augustine G.J., Schafer T. Proc. Natl. Acad. Sci. U.S.A. 94:12186-12191(1997) [PubMed: 9342384] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. |
| [4] | "X-ray structure of a neuronal complexin-SNARE complex from squid." Bracher A., Kadlec J., Betz H., Weissenhorn W. J. Biol. Chem. 277:26517-26523(2002) [PubMed: 12004067] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.95 ANGSTROMS) OF 183-265. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EMBL GenBank DDBJ | D78271 mRNA. Translation: BAA24019.1. Y14575 mRNA. Translation: CAA74913.1. | ||||||||||||||||||
3D structure databases | |||||||||||||||||||
| PDBe RCSB PDB PDBj |
| ||||||||||||||||||
| ProteinModelPortal | O46345. | ||||||||||||||||||
| SMR | O46345. Positions 32-259. | ||||||||||||||||||
| ModBase | Search... | ||||||||||||||||||
Protein-protein interaction databases | |||||||||||||||||||
| IntAct | O46345. 1 interaction. | ||||||||||||||||||
Protocols and materials databases | |||||||||||||||||||
| StructuralBiologyKnowledgebase | Search... | ||||||||||||||||||
Family and domain databases | |||||||||||||||||||
| InterPro | IPR006012. Syntaxin/epimorphin_CS. IPR006011. Syntaxin_N. IPR010989. t-SNARE. IPR000727. T_SNARE_dom. [Graphical view] | ||||||||||||||||||
| Pfam | PF05739. SNARE. 1 hit. PF00804. Syntaxin. 1 hit. [Graphical view] | ||||||||||||||||||
| SMART | SM00503. SynN. 1 hit. SM00397. t_SNARE. 1 hit. [Graphical view] | ||||||||||||||||||
| SUPFAM | SSF47661. t-snare. 1 hit. | ||||||||||||||||||
| PROSITE | PS00914. SYNTAXIN. 1 hit. PS50192. T_SNARE. 1 hit. [Graphical view] | ||||||||||||||||||
| ProtoNet | Search... | ||||||||||||||||||
Entry information
| Entry name | O46345_LOLPE | ||||||||
| Accession | Primary (citable) accession number: O46345 | ||||||||
| Entry history |
| ||||||||
| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with