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Protein
Submitted name:

Zinc-finger nuclear protein hindsight

Gene

peb

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • amnioserosa maintenance Source: FlyBase
  • compound eye development Source: FlyBase
  • dorsal closure Source: FlyBase
  • dorsal closure, leading edge cell fate determination Source: FlyBase
  • ectoderm development Source: FlyBase
  • establishment of ommatidial planar polarity Source: FlyBase
  • germ-band shortening Source: FlyBase
  • head involution Source: FlyBase
  • maintenance of epithelial integrity, open tracheal system Source: FlyBase
  • negative regulation of JNK cascade Source: UniProtKB
  • negative regulation of protein localization to plasma membrane Source: UniProtKB
  • negative regulation of STAT protein import into nucleus Source: UniProtKB
  • ommatidial rotation Source: FlyBase
  • open tracheal system development Source: FlyBase
  • photoreceptor cell morphogenesis Source: FlyBase
  • positive regulation of border follicle cell migration Source: UniProtKB
  • positive regulation of epithelial cell-cell adhesion involved in epithelium migration Source: UniProtKB
  • positive regulation of homophilic cell adhesion Source: UniProtKB
  • regulation of transcription, DNA-templated Source: FlyBase
  • regulation of tube architecture, open tracheal system Source: FlyBase
  • terminal region determination Source: FlyBase
  • torso signaling pathway Source: FlyBase
  • wing disc dorsal/ventral pattern formation Source: FlyBase
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc-finger nuclear protein hindsightImported
Gene namesi
Name:pebImported
Synonyms:hindsightImported
ORF Names:CG12212Imported
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0003053. peb.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: FlyBase
  • polytene chromosome Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

NucleusImported

PTM / Processingi

Proteomic databases

PaxDbiO46205.
PRIDEiO46205.

Expressioni

Gene expression databases

BgeeiFBgn0003053.
ExpressionAtlasiO46205. differential.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0070648.

Structurei

3D structure databases

ProteinModelPortaliO46205.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini282 – 30928C2H2-typeInterPro annotationAdd
BLAST
Domaini310 – 33728C2H2-typeInterPro annotationAdd
BLAST
Domaini709 – 73628C2H2-typeInterPro annotationAdd
BLAST
Domaini741 – 76828C2H2-typeInterPro annotationAdd
BLAST
Domaini769 – 79224C2H2-typeInterPro annotationAdd
BLAST
Domaini1059 – 108224C2H2-typeInterPro annotationAdd
BLAST
Domaini1448 – 147528C2H2-typeInterPro annotationAdd
BLAST
Domaini1623 – 165129C2H2-typeInterPro annotationAdd
BLAST
Domaini1701 – 172828C2H2-typeInterPro annotationAdd
BLAST
Domaini1729 – 176133C2H2-typeInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili415 – 44228Sequence analysisAdd
BLAST
Coiled coili1525 – 158662Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerImported

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
OrthoDBiEOG091G0AFV.
PhylomeDBiO46205.

Family and domain databases

Gene3Di3.30.160.60. 7 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 13 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 11 hits.
PS50157. ZINC_FINGER_C2H2_2. 10 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O46205-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAAQQQHNN STVVLEMERQ RRDSTTSESS LEHLDLGRTP KKLGGNSGST
60 70 80 90 100
QTTSTPHELA TVTSSRKRKI RHLQLNHHQQ QQHHQQSDLL SDEDVVEAEA
110 120 130 140 150
EEDEDDEDGD QVAALGSRNL GRHKQRRSGG ATTQASIVMD YSSGDASSLR
160 170 180 190 200
KKFRLNRSAA SLSESGFVDA SSTTGHSGYL GNSSSATNTT ATSGIGASAV
210 220 230 240 250
APSPVGGAAI NAASSSSGSS SGGSGGSSPQ GQCLSSGESG IGAGDEHMKY
260 270 280 290 300
LCPICEVVSA TPHEFTNHIR CHNYANGDTE NFTCRICSKV LSSASSLDRH
310 320 330 340 350
VLVHTGERPF NCRYCHLTFT TNGNMHRHMR THKQHQVAQS QSQSQQQQSL
360 370 380 390 400
QQQQQSQQQR RQQQQHQPSQ QQQNPAQQQL MGNTLSAGAE SYESDASCST
410 420 430 440 450
DVSSGHSHSR SSSSLNNNNN NSHKANNNLK DLEELEVSTE DQDTENKQRR
460 470 480 490 500
LKTTINNNII ESEQQEDMDD EEADDADVAM LTSTPDVATL LAGASASGAA
510 520 530 540 550
SRSPTPSPSA SPALLLSCPA CGASDFETLP ALCVHLDAMH SDIPAKCRDC
560 570 580 590 600
EVIFATHRQL QSHCCRLPNA LAGGLPPLLG ASSSPLHNEE PEDEEHGDDE
610 620 630 640 650
DLEQKERLAS QSEDFFHQLY LKHKTANGCG AISHPPSPIK HEPADTKDLA
660 670 680 690 700
DIQSILNMTS SSSSFLRNFE QSVNTPNSSQ YSLDGRDQEE EAQDAFTSEF
710 720 730 740 750
RRMKLRGEFP CKLCTAVFPN LRALKGHNRV HLGAVGPAGP FRCNMCPYAV
760 770 780 790 800
CDKAALVRHM RTHNGDRPYE CAVCNYAFTT KANCERHLRN RHGKTSREEV
810 820 830 840 850
KRAIVYHPAE DAGCEDSKSR LGEDLADTSF RSISPTPPPP PVNESKSQLK
860 870 880 890 900
HMLLGENHLA PVNQQPPLKI QVKSLDQLVD KKPSAPAPQQ QQQQQQQEKS
910 920 930 940 950
GSALDFSMDV LDLSKKPTGG ASLTPAVTRT PTPAAVAPVT PGGVGTPDLA
960 970 980 990 1000
AAIEQQQLLL AQQQLFGAGG EYMQQLFRSL MFQSQTSGFP FFPFMAPPPP
1010 1020 1030 1040 1050
QANPEKPPMV SPPNRINPMP VGVGVGVPVP PGGPVKMVIK NGVLMPKQKQ
1060 1070 1080 1090 1100
RRYRTERPFA CEHCSARFTL RSNMERHVKQ QHPQFYAQRE RSAHHVMRGR
1110 1120 1130 1140 1150
GASNVAAAAA AAAAAAAPTV MAGGPGSSGF GSNHHHGHGH GSHGHAPISE
1160 1170 1180 1190 1200
QVKCAILAQQ LKAHKNTDLL QQALAHGSSS VAGNPLLHFG YPLTNPSPMH
1210 1220 1230 1240 1250
NGSSQGNGQA TAMDDDEPKL IIDEDENEHD HEVEAEDVDD FEEDEDEEEM
1260 1270 1280 1290 1300
DEPEDEPELI LDEQPAEKEA EEEQELPKPL EQLGTKEAAQ KMAETILEQA
1310 1320 1330 1340 1350
IKAGKPLSPP PTKENASPAN PTVATTMQEP AITAPSTNPS SLKTMIAQAE
1360 1370 1380 1390 1400
YVGKSLKEVA SSPFKDESQD LVPVAKLVDN ATSQNMGFNS YFRPSDVANH
1410 1420 1430 1440 1450
MEQSDEEGLV ASGSASESNN SGTEDVTSSS SSSEPKKKSA YSLAPNRVSC
1460 1470 1480 1490 1500
PYCQRMFPWS SSLRRHILTH TGQKPFKCSH CPLLFTTKSN CDRHLLRKHG
1510 1520 1530 1540 1550
NVESAMSVYV PTEDVSEPIP VPKSVEEIEL EEQRRRQEAE REKELELERE
1560 1570 1580 1590 1600
RELERERELE RERQLEKEKE RERQQLIQKL AAQMNAAATA AAVVAAASAV
1610 1620 1630 1640 1650
NGGASGGPHG PIADALAGGD LPYKCHLCEG SFAERLQCLE HIKQAHAHEY
1660 1670 1680 1690 1700
ALLLAKGAIE TESLEANPHQ QPSQQAVHSD DEAPNGGGNR GKYPDYSNRK
1710 1720 1730 1740 1750
VICAFCLRRF WSTEDLRRHM RTHSGERPFQ CDICLRKFTL KHSMLRHMKK
1760 1770 1780 1790 1800
HSGRAHNGDT PGSDCSDDEQ VSSPPSTPHP TQPTSANNNN SCHNNNNNAN
1810 1820 1830 1840 1850
NNNNNNNNNN NNSSSKLGLK LHDLLDKASE WRASRLGEHK ENMGEATPSG
1860 1870 1880 1890 1900
ATVAGSDLIG NLLGISDQGI LNKLLSSRTR RPNFWVWTTS ERNSSDNRAT
1910 1920
PRAINTGVAA VLHRLTYTKA
Length:1,920
Mass (Da):208,975
Last modified:June 1, 1998 - v1
Checksum:iBA51E67584916AA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U86010 mRNA. Translation: AAB95640.1.
PIRiT13893.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U86010 mRNA. Translation: AAB95640.1.
PIRiT13893.

3D structure databases

ProteinModelPortaliO46205.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0070648.

Proteomic databases

PaxDbiO46205.
PRIDEiO46205.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

FlyBaseiFBgn0003053. peb.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
OrthoDBiEOG091G0AFV.
PhylomeDBiO46205.

Gene expression databases

BgeeiFBgn0003053.
ExpressionAtlasiO46205. differential.

Family and domain databases

Gene3Di3.30.160.60. 7 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 13 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 11 hits.
PS50157. ZINC_FINGER_C2H2_2. 10 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO46205_DROME
AccessioniPrimary (citable) accession number: O46205
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: September 7, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.