Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Accessory gland protein Acp62F

Gene

Acp62F

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Responsible for physiological and behavioral changes in mated female flies. May contribute to the toxicity of seminal fluid and the decreased life-span of mated females. May also affect neuromuscular events after mating concerning sperm storage and egg release.1 Publication

GO - Molecular functioni

  • peptidase inhibitor activity Source: FlyBase
  • serine-type endopeptidase inhibitor activity Source: FlyBase

GO - Biological processi

  • behavior Source: UniProtKB-KW
  • multicellular organism reproduction Source: FlyBase
  • negative regulation of proteolysis Source: FlyBase
  • regulation of proteolysis Source: FlyBase
  • sperm competition Source: FlyBase

Keywordsi

Biological processBehavior

Protein family/group databases

MEROPSiI08.002

Names & Taxonomyi

Protein namesi
Recommended name:
Accessory gland protein Acp62F
Gene namesi
Name:Acp62F
ORF Names:CG1262
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0020509 Acp62F

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000003431025 – 115Accessory gland protein Acp62FAdd BLAST91

Proteomic databases

PaxDbiO46202
PRIDEiO46202

Expressioni

Tissue specificityi

Seminal fluid.1 Publication

Gene expression databases

BgeeiFBgn0020509
ExpressionAtlasiO46202 differential
GenevisibleiO46202 DM

Interactioni

Protein-protein interaction databases

BioGridi63842, 5 interactors
DIPiDIP-20806N
IntActiO46202, 5 interactors
STRINGi7227.FBpp0072820

Structurei

3D structure databases

ProteinModelPortaliO46202
SMRiO46202
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 88TILAdd BLAST55

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000217509
InParanoidiO46202
OMAiRSDCPKD
OrthoDBiEOG091G0VBO
PhylomeDBiO46202

Family and domain databases

InterProiView protein in InterPro
IPR036084 Ser_inhib-like_sf
IPR002919 TIL_dom
PfamiView protein in Pfam
PF01826 TIL, 1 hit
SUPFAMiSSF57567 SSF57567, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O46202-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDMWSLKIC ACLGLLLLFK PIDSMGWQGP KVDCTANGTQ TECPVACPET
60 70 80 90 100
CEYSGNGPCV KMCGAPCVCK PGYVINERIP ACVLRSDCPK DVVRKEDMLL
110
GVSNFKCFSR NYNCS
Length:115
Mass (Da):12,570
Last modified:June 1, 1998 - v1
Checksum:i4326AA6F6C32291D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U85763 mRNA Translation: AAB96387.1
AY344325 Genomic DNA Translation: AAR05044.1
AY344326 Genomic DNA Translation: AAR05045.1
AY344327 Genomic DNA Translation: AAR05046.1
AY344328 Genomic DNA Translation: AAR05047.1
AY344329 Genomic DNA Translation: AAR05048.1
AY344330 Genomic DNA Translation: AAR05049.1
AY344331 Genomic DNA Translation: AAR05050.1
AY344332 Genomic DNA Translation: AAR05051.1
AY344333 Genomic DNA Translation: AAR05052.1
AY344334 Genomic DNA Translation: AAR05053.1
AY344335 Genomic DNA Translation: AAR05054.1
AY344336 Genomic DNA Translation: AAR05055.1
AY344337 Genomic DNA Translation: AAR05056.1
AY344338 Genomic DNA Translation: AAR05057.1
AY344339 Genomic DNA Translation: AAR05058.1
AY344340 Genomic DNA Translation: AAR05059.1
AY344341 Genomic DNA Translation: AAR05060.1
AY344342 Genomic DNA Translation: AAR05061.1
AY344343 Genomic DNA Translation: AAR05062.1
AY344344 Genomic DNA Translation: AAR05063.1
AE014296 Genomic DNA Translation: AAF47683.1
AY010608 Genomic DNA Translation: AAG35367.1
AY010609 Genomic DNA Translation: AAG35368.1
AY010610 Genomic DNA Translation: AAG35369.1
AY010611 Genomic DNA Translation: AAG35370.1
AY010612 Genomic DNA Translation: AAG35371.1
AY010613 Genomic DNA Translation: AAG35372.1
AY010614 Genomic DNA Translation: AAG35373.1
AY010615 Genomic DNA Translation: AAG35374.1
AY010616 Genomic DNA Translation: AAG35375.1
AY010617 Genomic DNA Translation: AAG35376.1
RefSeqiNP_523892.1, NM_079168.3
UniGeneiDm.2899

Genome annotation databases

EnsemblMetazoaiFBtr0072943; FBpp0072820; FBgn0020509
GeneIDi38340
KEGGidme:Dmel_CG1262

Similar proteinsi

Entry informationi

Entry nameiA62F_DROME
AccessioniPrimary (citable) accession number: O46202
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health