Unreviewed, UniProtKB/TrEMBL O46094 (O46094_DROME)

Names and origin

Protein names

Submitted name:
    CG3573 EMBL AAF45696.1
    EC=3.1.3.56
Submitted name:
    EG:86E4.5 protein EMBL CAA15931.1
    LD39196p EMBL AAV36976.1

Gene names

Name:	EG:86E4.5 EMBL AAV36976.1
ORF Names:	CG3573 FlyBase FBgn0023508, Dmel_CG3573 EMBL AAF45696.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	850 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dephosphorylation Non-traceable author statement. Source: FlyBase signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	inositol-polyphosphate 5-phosphatase activity Inferred from electronic annotation. Source: EC protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O46094-1 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 0B1D3033CDD392A1	FASTA	850	97,530
	10 20 30 40 50 60 MDTLSEAVAN GTATAATRTT KDIVKERFKE DETIEYIFEA YQIKGPEYSN RLLALVSSQS 70 80 90 100 110 120 GGTFAIIAFS YLRTPLSSAN ELIINKVFAI DHNFQLRQDS KSSITTQQFD LSTAEDGPIK 130 140 150 160 170 180 YYYYATESHH YEEFVAKVIS FKSTMAQHDP ETVLNFRWLN DYRQIGEVKQ ELKKRESEYI 190 200 210 220 230 240 VYKDIIIYCA TWNVNNKTCS DSNNPLRAWL ACSEKPPDIY AIGLQELDTP TKAMLNSTQV 250 260 270 280 290 300 QAIEKQWIDK MMDSVHPDVE YEILMSHRLV ATMLTVIVRK QLRQHIIRCR PKSVARGIFN 310 320 330 340 350 360 TLGNKGGVAI SLQLNEGNIC FVNSHLAAHM GYVEERNQDY NAIVEGIRFD DGRTISDHDH 370 380 390 400 410 420 IFWVGDLNYR IQEPPGQQRP GPLSDAQTYE LLLQYDQLRQ EMRRGKCFEG YTEGEIKFRP 430 440 450 460 470 480 TYKYDPGTDN YDSSEKQRAP AYCDRVLWKG TRIEQLAYNS IMEIRQSDHK PVYAVFQVKV 490 500 510 520 530 540 KTRDEVKYKR VQEEVLKAVD KRENDNQPQI NVEKTVIDFG TVRFNEPSTR DFNVYNNCPL 550 560 570 580 590 600 PVDFSFKEKD IHAICEPWLH VDPRQDSLLI DSARSIRLKM NANVRTIAGL LRKIRASDNF 610 620 630 640 650 660 DILILHVENG RDIFITVTGD YQPSCFGLSM ETMCRTDRPL SEYSQDQIKQ LMNDESPEYR 670 680 690 700 710 720 VTMPREFFLL IDYLYRQGSK QVGAFPSYDS RLSLGAQFNS VRDWLDTWSD DPFPANAETA 730 740 750 760 770 780 AQALLLLLDL PEHALLEPVV ENLLECTNKS QAMDYISLLS PPKRNVFMHL CMFLRAGIES 790 800 810 820 830 840 QFYDLHQVAS TFGRILLRST ERAAWMDYHS RCIQFMRLFI DTDVEAMGNG NEGAGTGTGS 850 GSGTRAGLQA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., Park S., Wan K., Yu C., Rubin G.M., Celniker S. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAV36976.1.
[4]	"Sequencing the distal X chromosome of Drosophila melanogaster." Ferraz C., Vidal S., Brun C., Bucheton A., Demaille J.G. Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[5]	Benos P. Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014298 Genomic DNA. Translation: AAF45696.1. BT016091 mRNA. Translation: AAV36976.1. AL021086 Genomic DNA. Translation: CAA15931.1.
RefSeq	NP_569962.2.
UniGene	Dm.3547
3D structure databases
HSSP	HSSP built from PDB template 1I9Z based on UniProtKB O43001.
ModBase	Search...
Protein-protein interaction databases
IntAct	O46094. 1 interaction.
Proteomic databases
PRIDE	O46094.
Genome annotation databases
Ensembl	FBgn0023508. Drosophila melanogaster. [Contig view]
GeneID	31157.
KEGG	dme:Dmel_CG3573.
NMPDR	fig|7227.3.peg.16146.
Organism-specific databases
FlyBase	FBgn0023508. CG3573.
Phylogenomic databases
HOGENOM	O46094.
OMA	O46094. EDETIEY.
Gene expression databases
ArrayExpress	O46094.
Family and domain databases
InterPro	IPR005135. Endo/exonuclease/phosphatase. IPR000300. IPPc. IPR000198. RhoGAP. [Graphical view]
Gene3D	G3DSA:1.10.555.10. RhoGAP. 1 hit.
Pfam	PF03372. Exo_endo_phos. 1 hit. [Graphical view]
SMART	SM00128. IPPc. 1 hit. SM00324. RhoGAP. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	772213.

Entry information

Entry name

O46094_DROME

Accession

Primary (citable) accession number: O46094

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	June 16, 2009
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)