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Protein
Submitted name:

GH08708p

Gene

Pex5

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • peroxisome organization Source: FlyBase
  • protein import into peroxisome matrix, docking Source: GO_Central
  • response to anesthetic Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-9033241 Peroxisomal protein import

Names & Taxonomyi

Protein namesi
Submitted name:
GH08708pImported
Submitted name:
Peroxin 5, isoform AImported
Gene namesi
Name:Pex5Imported
Synonyms:armImported, Dmel\CG14815Imported, DmelPex5Imported, EG:63B12.5Imported, PEX5Imported
ORF Names:CG14815Imported, Dmel_CG14815Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0023516 Pex5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 30HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiO46085

Expressioni

Gene expression databases

BgeeiFBgn0023516
ExpressionAtlasiO46085 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiO46085, 21 interactors
STRINGi7227.FBpp0070351

Structurei

3D structure databases

SMRiO46085
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini306 – 555TPR_REGIONInterPro annotationAdd BLAST250
Repeati306 – 339TPRPROSITE-ProRule annotationAdd BLAST34
Repeati340 – 373TPRPROSITE-ProRule annotationAdd BLAST34
Repeati374 – 407TPRPROSITE-ProRule annotationAdd BLAST34
Repeati454 – 487TPRPROSITE-ProRule annotationAdd BLAST34
Repeati488 – 521TPRPROSITE-ProRule annotationAdd BLAST34
Repeati522 – 555TPRPROSITE-ProRule annotationAdd BLAST34

Keywords - Domaini

TPR repeatPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1125 Eukaryota
ENOG410XQ6Q LUCA
OrthoDBiEOG091G07HM

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR024111 PTS1R_family
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR10130 PTHR10130, 2 hits
PfamiView protein in Pfam
PF13181 TPR_8, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 4 hits
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50005 TPR, 6 hits
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

O46085-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQSGIWRSK PILWRIRFCA AIYFIIIRAL CNTVTKPIAS ITADKQLRSI
60 70 80 90 100
STSNTMSFRP LVEGDCGGVN PLMQLGGQFT RDVAHKDEGY VQRHFERAAR
110 120 130 140 150
PEDQLINEFL GQVTAPPQSF QMDTLLQEMR DINIHGNPQQ QMHSQQAEQW
160 170 180 190 200
GQDFARGLAP ALPNKMIHMQ AQQQDLQHAQ EFFDEPLISS QNFRSLPPLR
210 220 230 240 250
QPLMPIAAGQ QQDPFFDSAM ETIITDHLPQ APQGESLDDW ISDYQRSTEQ
260 270 280 290 300
KEQTAANFNE KFWERLQDEW QKLADENEHP WLSEYNDNMD AYKEYEFAEG
310 320 330 340 350
NPMSDVENPF EKGKEYLSKG DIPSAVLCFE VAAKKQPERA EVWQLLGTSQ
360 370 380 390 400
TENEMDPQAI AALKRAYDLQ PDNQQVLMAL AACYTNEGLQ NNAVRMLCNW
410 420 430 440 450
LTVHPKYQHL VAAHPELQAE GTSLASSLIG PSKLRDLQQI YLEAVRQHPS
460 470 480 490 500
EVDAEVQDAL GVLYNLSGEF DKAVDCYQSA LQVDPQNAKT WNRLGASLAN
510 520 530 540 550
GSRSVEAVEA YQQALQLQPG FIRVRYNVGV CCMNLKAYKE AVEHLLTALT
560 570 580 590 600
MQAHTNAARE LPNAAMAATF RGQNQMSESI WSTLKMVISL MGRSDLQSYV
610
SDRNLAALNE AFKD
Length:614
Mass (Da):69,361
Last modified:July 5, 2004 - v2
Checksum:i69EA61A6E945E544
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF45676.2
AY118757 mRNA Translation: AAM50617.1
PIRiT12680
RefSeqiNP_726771.1, NM_166910.2
UniGeneiDm.11465

Genome annotation databases

EnsemblMetazoaiFBtr0070367; FBpp0070351; FBgn0023516
GeneIDi31141
UCSCiCG14815-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiO46085_DROME
AccessioniPrimary (citable) accession number: O46085
Secondary accession number(s): Q8MSJ5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 155 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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