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Protein

60S ribosomal protein L18

Gene

rpl-18

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L18
Gene namesi
Name:rpl-18
ORF Names:Y45F10D.12
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiY45F10D.12; CE16650; WBGene00004430; rpl-18.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 18818860S ribosomal protein L18PRO_0000291623Add
BLAST

Proteomic databases

EPDiO45946.
PaxDbiO45946.

Interactioni

Protein-protein interaction databases

BioGridi43426. 4 interactions.
DIPiDIP-25467N.
MINTiMINT-1068012.
STRINGi6239.Y45F10D.12.3.

Structurei

3D structure databases

ProteinModelPortaliO45946.
SMRiO45946. Positions 54-121.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L18e family.Curated

Phylogenomic databases

eggNOGiKOG1714. Eukaryota.
COG1727. LUCA.
GeneTreeiENSGT00390000012976.
HOGENOMiHOG000213425.
InParanoidiO45946.
KOiK02883.
OMAiIHRPPIS.
PhylomeDBiO45946.

Family and domain databases

InterProiIPR000039. Ribosomal_L18e.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PANTHERiPTHR10934. PTHR10934. 1 hit.
PfamiPF17135. Ribosomal_L18. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.

Sequencei

Sequence statusi: Complete.

O45946-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIDINHKHD RVARRTAPKS ENPYLRLLSK LYAFLARRTG EKFNAIVLKR
60 70 80 90 100
LRMSRRNRQP LSLAKLARAV QKAGNENKTV VTLSTVTDDA RLYTVPKISV
110 120 130 140 150
AALHVTEGAR ARILAAGGEI ITLDQLALKS PKGENTVFLQ GPRSAREAEK
160 170 180
HFGPAPGVPH SHTKPYVRSK GRKFERARGR RASRAYKN
Length:188
Mass (Da):20,996
Last modified:June 1, 1998 - v1
Checksum:i31FE0945F83B9E0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021492 Genomic DNA. Translation: CAA16387.1.
PIRiT26939.
RefSeqiNP_502655.1. NM_070254.4.
UniGeneiCel.34110.

Genome annotation databases

EnsemblMetazoaiY45F10D.12.1; Y45F10D.12.1; WBGene00004430.
Y45F10D.12.2; Y45F10D.12.2; WBGene00004430.
Y45F10D.12.3; Y45F10D.12.3; WBGene00004430.
GeneIDi178342.
KEGGicel:CELE_Y45F10D.12.
UCSCiY45F10D.12.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021492 Genomic DNA. Translation: CAA16387.1.
PIRiT26939.
RefSeqiNP_502655.1. NM_070254.4.
UniGeneiCel.34110.

3D structure databases

ProteinModelPortaliO45946.
SMRiO45946. Positions 54-121.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi43426. 4 interactions.
DIPiDIP-25467N.
MINTiMINT-1068012.
STRINGi6239.Y45F10D.12.3.

Proteomic databases

EPDiO45946.
PaxDbiO45946.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY45F10D.12.1; Y45F10D.12.1; WBGene00004430.
Y45F10D.12.2; Y45F10D.12.2; WBGene00004430.
Y45F10D.12.3; Y45F10D.12.3; WBGene00004430.
GeneIDi178342.
KEGGicel:CELE_Y45F10D.12.
UCSCiY45F10D.12.1. c. elegans.

Organism-specific databases

CTDi178342.
WormBaseiY45F10D.12; CE16650; WBGene00004430; rpl-18.

Phylogenomic databases

eggNOGiKOG1714. Eukaryota.
COG1727. LUCA.
GeneTreeiENSGT00390000012976.
HOGENOMiHOG000213425.
InParanoidiO45946.
KOiK02883.
OMAiIHRPPIS.
PhylomeDBiO45946.

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiO45946.

Family and domain databases

InterProiIPR000039. Ribosomal_L18e.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PANTHERiPTHR10934. PTHR10934. 1 hit.
PfamiPF17135. Ribosomal_L18. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiRL18_CAEEL
AccessioniPrimary (citable) accession number: O45946
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: June 1, 1998
Last modified: June 8, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.