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Protein
Submitted name:

Kinesin-like protein

Gene

klp-19

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • meiotic chromosome condensation Source: UniProtKB
  • meiotic spindle midzone assembly Source: UniProtKB
  • microtubule-based movement Source: GO_Central
Complete GO annotation...

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-983189. Kinesins.

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin-like proteinImported
Gene namesi
Name:klp-19Imported
ORF Names:CELE_Y43F4B.6Imported, Y43F4B.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiY43F4B.6; CE16631; WBGene00002229; klp-19.

Subcellular locationi

GO - Cellular componenti

  • chromosome Source: WormBase
  • condensed nuclear chromosome Source: WormBase
  • kinesin complex Source: GO_Central
  • nucleoplasm Source: WormBase
  • spindle Source: WormBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiO45935.
PaxDbiO45935.
PeptideAtlasiO45935.

Expressioni

Gene expression databases

BgeeiWBGene00002229.

Interactioni

Protein-protein interaction databases

DIPiDIP-24548N.
IntActiO45935. 1 interactor.
MINTiMINT-1078344.
STRINGi6239.Y43F4B.6.

Structurei

3D structure databases

ProteinModelPortaliO45935.
SMRiO45935.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 328Kinesin motorInterPro annotationAdd BLAST323

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili336 – 363Sequence analysisAdd BLAST28
Coiled coili408 – 435Sequence analysisAdd BLAST28
Coiled coili487 – 514Sequence analysisAdd BLAST28
Coiled coili522 – 618Sequence analysisAdd BLAST97

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0244. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00860000133670.
HOGENOMiHOG000016496.
InParanoidiO45935.
KOiK10395.
OMAiGGENCCV.
OrthoDBiEOG091G028H.
PhylomeDBiO45935.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 3 hits.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O45935-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDASLRVV VRARPMNGRE TKEGASRCVQ FYENTKQIVI NESATFTFDA
60 70 80 90 100
VFADTSDQES VYETTALPLL DRIFAGFNAT VLAYGQTGSG KTYTMGTEDN
110 120 130 140 150
VGTDEMRRGI IPRLVSALFQ RIMNTEAPES FAVTVSMFEV YGDNVYDLLR
160 170 180 190 200
PDKVKLNVHG DEKNCTVVNL TAVPVIDLKG ALKQLAVGCH YRTKAETAMN
210 220 230 240 250
AMSSRSHAVF TVFVEKTATA ECDSAFSAKL QLVDLAGSER LKKTEAEGNR
260 270 280 290 300
MKEGININGG LLILSQVIAA LATKQKHIPY RNSVITRVLQ DSLGGNSFTV
310 320 330 340 350
FLACISPADS NSQETLNTLR YADRAKQIKN KPIVNKNPKA EEIAILQAQL
360 370 380 390 400
KRLQKENADL KQGIAPAEVR FNDANNSAEI LSLKEEVVRK TEQLKERAMK
410 420 430 440 450
QSECIIRMSA LTQKNSRLEE DKAKLQSMLT DVRNTVLNEE MLDAAEVVRS
460 470 480 490 500
IQQVVGDTEE STTLADDDND ETALGGQDDT IYDTERLPEL QAELDDLEKQ
510 520 530 540 550
IAMKDENRQK ALDEQRAFIE AMQQRESEKT QLVVRISELE TEMNKLRQEG
560 570 580 590 600
KKVTTAAKLA EERRQKLKDL ERQHAEDKKV LNDMKKLQET RRRMEETLKK
610 620 630 640 650
TEDELKNLKT QRLRLLREQR AEASKFQAFK QKHEREMAQM KSKLQKREND
660 670 680 690 700
VAIQKRMTDQ KLTVLQMRLT EANRANKTLR ELNLKRANRK SSPTNASALQ
710 720 730 740 750
NMIEEELEHE MCAQRSHWLC EDLRRQRHDL MQNINTVESM KFEGGKRRRI
760 770 780 790 800
SASADPNVSV VIEGEEEFEV KRQKELTFLR ASLETLNEEI KDSLRNETIA
810 820 830 840 850
GNEERANSRW EKVPAEMRPA FEAVYAQAVA HIRKEIELEF KLARTKSEFT
860 870 880 890 900
AKIASKASHE EKRKKEDEEM RAKYRELAQC LEDAKSGLHE KIAFLLCLIK
910 920 930 940 950
ENRVDENAIQ QFESLKNQFC DVEQKVKKAS RRKTTNFMGG LTPKPELQRN
960 970 980 990 1000
ERARRAVKYY GNVVNSEDVT MDDSRHQKRK DHSLLAVEMN RTTDDNVKRR
1010 1020 1030 1040 1050
VAMSPIKCDD DTRLTEEDED IENEAMNNAT FVKDSFNSAT IVLDDSQPSP
1060 1070 1080
SNSTFVIGAA PTSEADGVPP IKRKSRRTDL GPL
Length:1,083
Mass (Da):123,139
Last modified:June 1, 1998 - v1
Checksum:i2410A98C7C142D81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CAA16335.1.
PIRiT26844.
RefSeqiNP_499742.1. NM_067341.3.
UniGeneiCel.22471.

Genome annotation databases

EnsemblMetazoaiY43F4B.6; Y43F4B.6; WBGene00002229.
GeneIDi176750.
KEGGicel:CELE_Y43F4B.6.
UCSCiY43F4B.6.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CAA16335.1.
PIRiT26844.
RefSeqiNP_499742.1. NM_067341.3.
UniGeneiCel.22471.

3D structure databases

ProteinModelPortaliO45935.
SMRiO45935.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-24548N.
IntActiO45935. 1 interactor.
MINTiMINT-1078344.
STRINGi6239.Y43F4B.6.

Proteomic databases

EPDiO45935.
PaxDbiO45935.
PeptideAtlasiO45935.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY43F4B.6; Y43F4B.6; WBGene00002229.
GeneIDi176750.
KEGGicel:CELE_Y43F4B.6.
UCSCiY43F4B.6.1. c. elegans.

Organism-specific databases

CTDi176750.
WormBaseiY43F4B.6; CE16631; WBGene00002229; klp-19.

Phylogenomic databases

eggNOGiKOG0244. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00860000133670.
HOGENOMiHOG000016496.
InParanoidiO45935.
KOiK10395.
OMAiGGENCCV.
OrthoDBiEOG091G028H.
PhylomeDBiO45935.

Enzyme and pathway databases

ReactomeiR-CEL-983189. Kinesins.

Gene expression databases

BgeeiWBGene00002229.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 3 hits.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO45935_CAEEL
AccessioniPrimary (citable) accession number: O45935
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: November 30, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.