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Protein
Submitted name:

CYclin B

Gene

cyb-2.1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

  • anterior/posterior axis specification, embryo Source: WormBase
  • oocyte maturation Source: WormBase
Complete GO annotation...

Keywords - Molecular functioni

CyclinUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-CEL-113507. E2F-enabled inhibition of pre-replication complex formation.
R-CEL-176408. Regulation of APC/C activators between G1/S and early anaphase.
R-CEL-2299718. Condensation of Prophase Chromosomes.
R-CEL-4419969. Depolymerisation of the Nuclear Lamina.
R-CEL-6804114. TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest.
R-CEL-69273. Cyclin A/B1 associated events during G2/M transition.
R-CEL-69478. G2/M DNA replication checkpoint.

Names & Taxonomyi

Protein namesi
Submitted name:
CYclin BImported
Gene namesi
Name:cyb-2.1Imported
ORF Names:CELE_Y43E12A.1Imported, Y43E12A.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiY43E12A.1; CE28122; WBGene00000866; cyb-2.1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO45926.
PeptideAtlasiO45926.

Expressioni

Gene expression databases

BgeeiWBGene00000866.

Interactioni

Protein-protein interaction databases

IntActiO45926. 3 interactors.
MINTiMINT-251238.
STRINGi6239.Y43E12A.1.

Structurei

3D structure databases

ProteinModelPortaliO45926.
SMRiO45926.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 94Cyclin N-terminalInterPro annotationAdd BLAST32

Sequence similaritiesi

Belongs to the cyclin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0653. Eukaryota.
COG5024. LUCA.
GeneTreeiENSGT00760000118939.
HOGENOMiHOG000021215.
InParanoidiO45926.
KOiK05868.
OMAiYNMESET.
OrthoDBiEOG091G0E9B.
PhylomeDBiO45926.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
InterProiIPR013763. Cyclin-like.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
SM01332. Cyclin_C. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.
PROSITEiPS00292. CYCLINS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O45926-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRVTTSIRK TTKNAVGPRT NLEEVLNCIA MAEDIYNYLV HHEKKYVLDD
60 70 80 90 100
SFINGGNVNS KMRRILVDWL IQVHLRFHLT PETLHLTIFV LDRIIVKNIV
110 120 130 140 150
SKAEFQLLGV AALFVASKFE DIYLPDILEY EMITDNTFSK KQIMAMEQTI
160 170 180 190 200
LNALNFDLSC PSSLVFLRCI SKTLTENDVN PIDKEAFYYV HNISKCLGEL
210 220 230 240 250
ALLDSVMSTV PRSHVASASM IITLNVITVD GINPKTAASM IRKQLGASKQ
260 270 280 290 300
DIYDAIALLA QVAYKNFRHQ KLCAIREKYQ SSKFGRVSYL MTDEILEKIH
310
RMGRNVEASE AETSEME
Length:317
Mass (Da):36,031
Last modified:October 1, 2001 - v2
Checksum:i98A9C1AC273AF18E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA15975.2.
PIRiT26832.
RefSeqiNP_502047.1. NM_069646.4.
UniGeneiCel.23433.

Genome annotation databases

EnsemblMetazoaiY43E12A.1; Y43E12A.1; WBGene00000866.
GeneIDi177994.
KEGGicel:CELE_Y43E12A.1.
UCSCiY43E12A.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA15975.2.
PIRiT26832.
RefSeqiNP_502047.1. NM_069646.4.
UniGeneiCel.23433.

3D structure databases

ProteinModelPortaliO45926.
SMRiO45926.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO45926. 3 interactors.
MINTiMINT-251238.
STRINGi6239.Y43E12A.1.

Proteomic databases

PaxDbiO45926.
PeptideAtlasiO45926.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY43E12A.1; Y43E12A.1; WBGene00000866.
GeneIDi177994.
KEGGicel:CELE_Y43E12A.1.
UCSCiY43E12A.1. c. elegans.

Organism-specific databases

CTDi177994.
WormBaseiY43E12A.1; CE28122; WBGene00000866; cyb-2.1.

Phylogenomic databases

eggNOGiKOG0653. Eukaryota.
COG5024. LUCA.
GeneTreeiENSGT00760000118939.
HOGENOMiHOG000021215.
InParanoidiO45926.
KOiK05868.
OMAiYNMESET.
OrthoDBiEOG091G0E9B.
PhylomeDBiO45926.

Enzyme and pathway databases

ReactomeiR-CEL-113507. E2F-enabled inhibition of pre-replication complex formation.
R-CEL-176408. Regulation of APC/C activators between G1/S and early anaphase.
R-CEL-2299718. Condensation of Prophase Chromosomes.
R-CEL-4419969. Depolymerisation of the Nuclear Lamina.
R-CEL-6804114. TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest.
R-CEL-69273. Cyclin A/B1 associated events during G2/M transition.
R-CEL-69478. G2/M DNA replication checkpoint.

Gene expression databases

BgeeiWBGene00000866.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
InterProiIPR013763. Cyclin-like.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
SM01332. Cyclin_C. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.
PROSITEiPS00292. CYCLINS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO45926_CAEEL
AccessioniPrimary (citable) accession number: O45926
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: October 1, 2001
Last modified: November 30, 2016
This is version 128 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.