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Protein
Submitted name:

Uncharacterized protein

Gene

mlt-11

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

MEROPSiI02.955.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:mlt-11Imported
ORF Names:CELE_W01F3.3Imported, W01F3.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiW01F3.3a; CE40239; WBGene00012186; mlt-11.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 21752158Sequence analysisPRO_5004158528Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

EPDiO45881.
PaxDbiO45881.

Expressioni

Gene expression databases

ExpressionAtlasiO45881. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiO45881. 1 interaction.
MINTiMINT-3384579.
STRINGi6239.W01F3.3b.

Structurei

3D structure databases

ProteinModelPortaliO45881.
SMRiO45881. Positions 423-473, 539-590, 737-921, 1081-1134, 1223-1337, 1788-1838, 2114-2175.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini345 – 40965Thyroglobulin type-1InterPro annotationAdd
BLAST
Domaini423 – 47351BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST
Domaini539 – 58951BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST
Domaini737 – 78751BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST
Domaini804 – 85451BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST
Domaini866 – 91651BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST
Domaini1083 – 113351BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST
Domaini1223 – 127351BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST
Domaini1287 – 133751BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST
Domaini1788 – 183851BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST
Domaini2117 – 217458BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili682 – 70625Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 10 BPTI/Kunitz inhibitor domains.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4295. Eukaryota.
ENOG410XQNP. LUCA.
GeneTreeiENSGT00740000114929.
HOGENOMiHOG000017856.
OrthoDBiEOG73FQKT.

Family and domain databases

Gene3Di4.10.410.10. 10 hits.
4.10.800.10. 1 hit.
InterProiIPR006150. Cys_repeat_1.
IPR002223. Kunitz_BPTI.
IPR028150. Lustrin_cystein.
IPR020901. Prtase_inh_Kunz-CS.
IPR000716. Thyroglobulin_1.
[Graphical view]
PfamiPF00014. Kunitz_BPTI. 10 hits.
PF14625. Lustrin_cystein. 3 hits.
PF00086. Thyroglobulin_1. 1 hit.
[Graphical view]
PRINTSiPR00759. BASICPTASE.
SMARTiSM00131. KU. 10 hits.
SM00211. TY. 1 hit.
SM00289. WR1. 4 hits.
[Graphical view]
SUPFAMiSSF57362. SSF57362. 10 hits.
SSF57610. SSF57610. 1 hit.
PROSITEiPS00280. BPTI_KUNITZ_1. 8 hits.
PS50279. BPTI_KUNITZ_2. 10 hits.
PS00484. THYROGLOBULIN_1_1. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O45881-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLCVLLLAA LVVATEAVDP CKRQPFRGRC PSQNGETPKR SQFVLRYYLR
60 70 80 90 100
NGECVSYPYG HCATDPTEPN LYRYKEECED ACISNAPANL GVPKSTTEDY
110 120 130 140 150
QKEILSKEVK RVEFYVTSTL NYGAPVDTTT IRNVYPLPVT TTETQAPPHH
160 170 180 190 200
TTKPYQYHYT SPTTTTTKRP PTTTTTEDPQ PFEFHELQEQ AENPIPLDPK
210 220 230 240 250
NSLQETSEQV DEQPFNFKEP TNSASDGSQQ SVESTTTTTE SPTTEASTTT
260 270 280 290 300
TEAPTTTTSE EVTTTEITTE APTTTEEVTT TETTIEAQTT TTTERMSPST
310 320 330 340 350
TKTSTTTTAK PTTTRSTTTQ RPQTVATTEA PTTTTVEDVT TRAPRTECER
360 370 380 390 400
RRASASSSSI RGGFVPACTA SGDFERVQCE TNGRQCFCVN TQGIEVPNSR
410 420 430 440 450
TRDGTRPDCY SIQSSRTVNT KECVGVSLPG PCHGSFQRYF YNEDSQKCEQ
460 470 480 490 500
FTYSGCGGNG NNYESREACE DRCAPPPVGL PKCEIGEPLK TKIGVPVNCA
510 520 530 540 550
KTDCPSGYRC SVVQHSSVCC PENNKVVGLQ TSGARATRCS LPKERGPCDK
560 570 580 590 600
YELRFYFNAD LNECKYFFWG GCEGNQNNFE RVEDCESACG VQKSGVTNRP
610 620 630 640 650
NTEIRTTQGI RITPNGGKLS WEETEEDEEH AVPTTTPLAP SAPTVRVSTQ
660 670 680 690 700
RAPVPTTPRP TAPAVQTTTT RASRLETTRV PVKTVEDEEE EEEEVVEEEQ
710 720 730 740 750
EDGKEEPPLH VQPPVSQQNT VLLGGIEDTT TDSVNRCLHP RDSGNCRGQF
760 770 780 790 800
VRWFFDDEKK NCDVFTYTGC QGNGNNFASK EECMAICHKP EPTPSATPDF
810 820 830 840 850
SQVCSNDVDA GECNGVFERF AFDAEAQDCR AFTYGGCGGN GNNFATMQEC
860 870 880 890 900
RSRCVMAMKK SPVATCEADI EVGECAGVFS RFAFDKSINA CRSFTYGGCG
910 920 930 940 950
GNANNFATLQ ECTNKCVNRG VCPEPPACDT NRCQLVNDRS GCPFCSCPPV
960 970 980 990 1000
KQASPPGSIT SIPKESLPNC PPLDRSACRD PCMMFHNRQG CEECICPQTA
1010 1020 1030 1040 1050
PTPPHVPTGR PTTVGQAQPP ASSSRRVTEV GPPAPRTTEA APPAPSSQPP
1060 1070 1080 1090 1100
RQFAVNTLQH QQTKPDQLPN LPRNLAAQIE EKCLQPVEPG PCKNFADRWY
1110 1120 1130 1140 1150
FNVDDGTCHP FKYGGCAGNR NHFFTQKECE VHCARFLKPV RAAGSKTLEA
1160 1170 1180 1190 1200
VKAVETVKQH KEQEPNGISR TMENVNLDLT ESAPTGLPVS IVTAAPTVQA
1210 1220 1230 1240 1250
SVVPLGTTPQ PHFEPKFDGR VVCAMPPDAG VCTNYTPRWF FNSQTGQCEQ
1260 1270 1280 1290 1300
FAYGSCGGNE NNFFDRNTCE RKCMPHHVIL AQVPDRCSFD KDSGSGKGYN
1310 1320 1330 1340 1350
VKWYFNMKNL RCEQFVFEGL GGNTNQFETL SECERICTPS GPKTPTLPPT
1360 1370 1380 1390 1400
PTPATVAVPV PAQTPKVPQL PIGAPGSQVP LPTPTTVIEK TTPTVVDSQE
1410 1420 1430 1440 1450
EEYDDEEEDP IILPETNEMP PMPGLAPANT FGTSQFGVNG LIDDNVELRL
1460 1470 1480 1490 1500
PEVATTSRIA IPQVPTTVAP VAPVAPVAQP VQPIQPVQPV QSVQSLPQPA
1510 1520 1530 1540 1550
EIPRVVVPQS PGTPQPVVPQ VSIVTPQAPQ PTAAATSAST GPIAPEPTTA
1560 1570 1580 1590 1600
APTTTETTPL PPSLAPHPPA AHAAKTVIPT YKAEPVLGRE QIPTANDGQP
1610 1620 1630 1640 1650
IVGASPKETV NYQTGAKASG IRSFDGSQDQ KISVDIFNKG ADGPTKSING
1660 1670 1680 1690 1700
MPACANGRTE VRYSDGRPVM CLPGKNQCPD GSSCYFNGID FFCCPEEEDP
1710 1720 1730 1740 1750
YDKHAFGGYG GDETKNGYKV FGALNIRRLM DEVPLRQKRQ TFGNSNSFNI
1760 1770 1780 1790 1800
DSVVAPLRFD AEKPRQVSRA LRMKSSAAVP RHGANPLCIQ PVVKGSCQEA
1810 1820 1830 1840 1850
HLRYYYDRVT DSCRLFEYSG CDGNANNFGS LEDCQRLCVL NIQSIKNGKV
1860 1870 1880 1890 1900
ATTTAAPQIT PEEEEKLAPG QCPGGRAPLG GSSPVLCGNS AESIGCPTSY
1910 1920 1930 1940 1950
YCRRGPPDVC CPGVDPKLMQ PEEIVKDVSR GVVKNESHMP RGFNRQIFLS
1960 1970 1980 1990 2000
TPKYMCPDAA DPLMLENGEP MLCGSGFDGV KMCPKGYYCA IDSARNSRLC
2010 2020 2030 2040 2050
CPLYGDAQRI ASEEIFAPRL ASNTETTTEA KVENIDVEES EDDEEEDGED
2060 2070 2080 2090 2100
FVAHLQMKPN KPVNQVEELA KSSPIAADLS AEGGVSIDLG ADEKKEVEEE
2110 2120 2130 2140 2150
DVTTTTEKMM VQDKSVCQIK PSEGRVCNDS ETPTRTNLQY FYSPRDNRCK
2160 2170
LFFFRGCGGN LNRFERKSDC EALCL
Length:2,175
Mass (Da):236,668
Last modified:June 13, 2006 - v2
Checksum:i3B4D82EE3832568E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAB07294.2.
PIRiT26063.
RefSeqiNP_001256940.1. NM_001270011.1.
UniGeneiCel.20885.

Genome annotation databases

EnsemblMetazoaiW01F3.3a; W01F3.3a; WBGene00012186.
GeneIDi180352.
UCSCiW01F3.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAB07294.2.
PIRiT26063.
RefSeqiNP_001256940.1. NM_001270011.1.
UniGeneiCel.20885.

3D structure databases

ProteinModelPortaliO45881.
SMRiO45881. Positions 423-473, 539-590, 737-921, 1081-1134, 1223-1337, 1788-1838, 2114-2175.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO45881. 1 interaction.
MINTiMINT-3384579.
STRINGi6239.W01F3.3b.

Protein family/group databases

MEROPSiI02.955.

Proteomic databases

EPDiO45881.
PaxDbiO45881.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiW01F3.3a; W01F3.3a; WBGene00012186.
GeneIDi180352.
UCSCiW01F3.3. c. elegans.

Organism-specific databases

CTDi180352.
WormBaseiW01F3.3a; CE40239; WBGene00012186; mlt-11.

Phylogenomic databases

eggNOGiKOG4295. Eukaryota.
ENOG410XQNP. LUCA.
GeneTreeiENSGT00740000114929.
HOGENOMiHOG000017856.
OrthoDBiEOG73FQKT.

Miscellaneous databases

NextBioi908990.

Gene expression databases

ExpressionAtlasiO45881. baseline and differential.

Family and domain databases

Gene3Di4.10.410.10. 10 hits.
4.10.800.10. 1 hit.
InterProiIPR006150. Cys_repeat_1.
IPR002223. Kunitz_BPTI.
IPR028150. Lustrin_cystein.
IPR020901. Prtase_inh_Kunz-CS.
IPR000716. Thyroglobulin_1.
[Graphical view]
PfamiPF00014. Kunitz_BPTI. 10 hits.
PF14625. Lustrin_cystein. 3 hits.
PF00086. Thyroglobulin_1. 1 hit.
[Graphical view]
PRINTSiPR00759. BASICPTASE.
SMARTiSM00131. KU. 10 hits.
SM00211. TY. 1 hit.
SM00289. WR1. 4 hits.
[Graphical view]
SUPFAMiSSF57362. SSF57362. 10 hits.
SSF57610. SSF57610. 1 hit.
PROSITEiPS00280. BPTI_KUNITZ_1. 8 hits.
PS50279. BPTI_KUNITZ_2. 10 hits.
PS00484. THYROGLOBULIN_1_1. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO45881_CAEEL
AccessioniPrimary (citable) accession number: O45881
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 13, 2006
Last modified: May 11, 2016
This is version 125 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.