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Protein
Submitted name:

Adenine Nucleotide Translocator

Gene

ant-1.1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • determination of adult lifespan Source: WormBase
  • mitochondrion organization Source: WormBase
  • positive regulation of apoptotic process Source: WormBase
  • transmembrane transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-CEL-422356. Regulation of insulin secretion.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenine Nucleotide TranslocatorImported
Gene namesi
Name:ant-1.1Imported
ORF Names:CELE_T27E9.1Imported, T27E9.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiT27E9.1a; CE14263; WBGene00006439; ant-1.1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei175 – 194HelicalSequence analysisAdd BLAST20
Transmembranei214 – 235HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • mitochondrial inner membrane Source: InterPro
  • mitochondrion Source: WormBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiO45865.
PaxDbiO45865.
PeptideAtlasiO45865.
PRIDEiO45865.

Expressioni

Gene expression databases

BgeeiWBGene00006439.
ExpressionAtlasiO45865. differential.

Interactioni

Protein-protein interaction databases

DIPiDIP-26385N.
IntActiO45865. 6 interactors.
MINTiMINT-1050033.
STRINGi6239.T27E9.1a.2.

Structurei

3D structure databases

ProteinModelPortaliO45865.
SMRiO45865.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
GeneTreeiENSGT00390000011543.
HOGENOMiHOG000165727.
InParanoidiO45865.
KOiK05863.
OMAiWRFADEN.
OrthoDBiEOG091G0ULB.
PhylomeDBiO45865.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O45865-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKEKSFDTK KFLIDLASGG TAAAVSKTAV APIERVKLLL QVQDASKAIA
60 70 80 90 100
VDKRYKGIMD VLIRVPKEQG VAALWRGNLA NVIRYFPTQA MNFAFKDTYK
110 120 130 140 150
AIFLEGLDKK KDFWKFFAGN LASGGAAGAT SLCFVYPLDF ARTRLAADIG
160 170 180 190 200
KANDREFKGL ADCLIKIVKS DGPIGLYRGF FVSVQGIIIY RAAYFGMFDT
210 220 230 240 250
AKMVFASDGQ KLNFFAAWGI AQVVTVGSGI LSYPWDTVRR RMMMQSGRKD
260 270 280 290 300
ILYKNTLDCA KKIIQNEGMS AMFKGALSNV FRGTGGALVL AIYDEIQKFL
Length:300
Mass (Da):33,045
Last modified:June 1, 1998 - v1
Checksum:i8E50F7DDA5933C6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CAB04874.1.
PIRiT25371.
RefSeqiNP_001022799.1. NM_001027628.5.
UniGeneiCel.17955.
Cel.38047.

Genome annotation databases

EnsemblMetazoaiT27E9.1a.1; T27E9.1a.1; WBGene00006439.
T27E9.1a.2; T27E9.1a.2; WBGene00006439.
T27E9.1a.3; T27E9.1a.3; WBGene00006439.
GeneIDi176773.
KEGGicel:CELE_T27E9.1.
UCSCiT27E9.1a.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CAB04874.1.
PIRiT25371.
RefSeqiNP_001022799.1. NM_001027628.5.
UniGeneiCel.17955.
Cel.38047.

3D structure databases

ProteinModelPortaliO45865.
SMRiO45865.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-26385N.
IntActiO45865. 6 interactors.
MINTiMINT-1050033.
STRINGi6239.T27E9.1a.2.

Proteomic databases

EPDiO45865.
PaxDbiO45865.
PeptideAtlasiO45865.
PRIDEiO45865.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT27E9.1a.1; T27E9.1a.1; WBGene00006439.
T27E9.1a.2; T27E9.1a.2; WBGene00006439.
T27E9.1a.3; T27E9.1a.3; WBGene00006439.
GeneIDi176773.
KEGGicel:CELE_T27E9.1.
UCSCiT27E9.1a.1. c. elegans.

Organism-specific databases

CTDi176773.
WormBaseiT27E9.1a; CE14263; WBGene00006439; ant-1.1.

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
GeneTreeiENSGT00390000011543.
HOGENOMiHOG000165727.
InParanoidiO45865.
KOiK05863.
OMAiWRFADEN.
OrthoDBiEOG091G0ULB.
PhylomeDBiO45865.

Enzyme and pathway databases

ReactomeiR-CEL-422356. Regulation of insulin secretion.

Gene expression databases

BgeeiWBGene00006439.
ExpressionAtlasiO45865. differential.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO45865_CAEEL
AccessioniPrimary (citable) accession number: O45865
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: November 30, 2016
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.