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Protein

Regulator of G-protein signaling rgs-11

Gene

rgs-11

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Signal transduction inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Regulator of G-protein signaling rgs-11
Gene namesi
Name:rgs-11
ORF Names:F45B8.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF45B8.1; CE10428; WBGene00004354; rgs-11.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 274274Regulator of G-protein signaling rgs-11PRO_0000223576Add
BLAST

Proteomic databases

PaxDbiO45524.

Interactioni

Protein-protein interaction databases

STRINGi6239.F45B8.1.

Structurei

3D structure databases

ProteinModelPortaliO45524.
SMRiO45524. Positions 127-256.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini137 – 256120RGSPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 RGS domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3589. Eukaryota.
ENOG410YMJD. LUCA.
GeneTreeiENSGT00530000065130.
HOGENOMiHOG000153585.
InParanoidiO45524.
PhylomeDBiO45524.

Family and domain databases

Gene3Di1.10.196.10. 2 hits.
InterProiIPR016137. RGS.
IPR024066. RGS_subdom1.
[Graphical view]
PfamiPF00615. RGS. 1 hit.
[Graphical view]
PRINTSiPR01301. RGSPROTEIN.
SMARTiSM00315. RGS. 1 hit.
[Graphical view]
SUPFAMiSSF48097. SSF48097. 1 hit.
PROSITEiPS50132. RGS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O45524-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIAITSPCQ IFPAIINADV YEKNLKVDDN AINVSKYSDN SVSLPTLSYE
60 70 80 90 100
DFHHFSVVRH WNILFPYRLA TEWNWESRRL RKRDALVILE LVALSDETNK
110 120 130 140 150
RGSVSRIMNT VRSKVHLMFS SSTELPSFQE IENWKKSPGL LAASKYGCAL
160 170 180 190 200
FIQFLKQQTS ENEVDFWLDC QKFRSSTAKI SWKNKEVHRI LDQFLSSSAP
210 220 230 240 250
RKIDMETSIL ARCMEYVEHI EGWKYTFDVA QAYVGLKFPK ESHKKFLEDP
260 270
LYLDLLELVI SGRSCNKVGH KKSC
Length:274
Mass (Da):31,743
Last modified:June 1, 1998 - v1
Checksum:i76E3742FEB47CFBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83227 Genomic DNA. Translation: CAB05728.1.
PIRiT22214.
RefSeqiNP_510483.1. NM_078082.4.
UniGeneiCel.6529.

Genome annotation databases

EnsemblMetazoaiF45B8.1; F45B8.1; WBGene00004354.
GeneIDi181590.
KEGGicel:CELE_F45B8.1.
UCSCiF45B8.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83227 Genomic DNA. Translation: CAB05728.1.
PIRiT22214.
RefSeqiNP_510483.1. NM_078082.4.
UniGeneiCel.6529.

3D structure databases

ProteinModelPortaliO45524.
SMRiO45524. Positions 127-256.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F45B8.1.

Proteomic databases

PaxDbiO45524.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF45B8.1; F45B8.1; WBGene00004354.
GeneIDi181590.
KEGGicel:CELE_F45B8.1.
UCSCiF45B8.1. c. elegans.

Organism-specific databases

CTDi181590.
WormBaseiF45B8.1; CE10428; WBGene00004354; rgs-11.

Phylogenomic databases

eggNOGiKOG3589. Eukaryota.
ENOG410YMJD. LUCA.
GeneTreeiENSGT00530000065130.
HOGENOMiHOG000153585.
InParanoidiO45524.
PhylomeDBiO45524.

Miscellaneous databases

NextBioi914570.
PROiO45524.

Family and domain databases

Gene3Di1.10.196.10. 2 hits.
InterProiIPR016137. RGS.
IPR024066. RGS_subdom1.
[Graphical view]
PfamiPF00615. RGS. 1 hit.
[Graphical view]
PRINTSiPR01301. RGSPROTEIN.
SMARTiSM00315. RGS. 1 hit.
[Graphical view]
SUPFAMiSSF48097. SSF48097. 1 hit.
PROSITEiPS50132. RGS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiRGS11_CAEEL
AccessioniPrimary (citable) accession number: O45524
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: June 1, 1998
Last modified: May 11, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.