Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nuclear hormone receptor family member nhr-111

Gene

nhr-111

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Orphan nuclear receptor.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi39 – 115Nuclear receptorPROSITE-ProRule annotationAdd BLAST77
Zinc fingeri42 – 62NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri78 – 98NR C4-typePROSITE-ProRule annotationAdd BLAST21

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Receptor
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

SignaLinkiO45521

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear hormone receptor family member nhr-111
Gene namesi
Name:nhr-111
ORF Names:F44G3.9
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF44G3.9 ; CE35538 ; WBGene00003701 ; nhr-111

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002235891 – 311Nuclear hormone receptor family member nhr-111Add BLAST311

Proteomic databases

PaxDbiO45521
PRIDEiO45521

Expressioni

Gene expression databases

BgeeiWBGene00003701

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi50516, 65 interactors
DIPiDIP-26766N
IntActiO45521, 99 interactors
STRINGi6239.F44G3.9

Structurei

3D structure databases

ProteinModelPortaliO45521
SMRiO45521
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini116 – 311NR LBDPROSITE-ProRule annotationAdd BLAST196

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri42 – 62NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri78 – 98NR C4-typePROSITE-ProRule annotationAdd BLAST21

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00870000136388
HOGENOMiHOG000260820
InParanoidiO45521
OMAiHAQHEID
OrthoDBiEOG091G0AV3
PhylomeDBiO45521

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

O45521-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSQNAKSIG GILETSTVPL VIQPQIVNDP AQNNITLPIT LCAVCGDTSN
60 70 80 90 100
GNHYGVPTCF GCSGFFRRTV RNKLVHGCWN GDGNCVIDKA NRNRCKSCRI
110 120 130 140 150
KKCFKKGMNK NAVQPERTSH SYTVEYVELP SFREYSKGLL PTHSDRLRFQ
160 170 180 190 200
HEHAQHEIDT SSVLVHLKNA LQWVQQFSLF AVLSDVEKSQ IILTQWPHLL
210 220 230 240 250
CLALFENSEK IFIDEKFAQL AEKFKSLELS AQDYFLLKGI IIFTETKDGT
260 270 280 290 300
DLKFDRQLDI CIGLLNQLHL ESSKSKSGRL LFLLGELKSY STRQLESLLD
310
LKACEIVISF L
Length:311
Mass (Da):35,145
Last modified:July 5, 2004 - v2
Checksum:i3F54D39BA3732AA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83109 Genomic DNA Translation: CAB05521.2
PIRiT22203
RefSeqiNP_507060.2, NM_074659.2
UniGeneiCel.3575

Genome annotation databases

EnsemblMetazoaiF44G3.9; F44G3.9; WBGene00003701
GeneIDi185757
KEGGicel:CELE_F44G3.9
UCSCiF44G3.9 c. elegans

Entry informationi

Entry nameiNH111_CAEEL
AccessioniPrimary (citable) accession number: O45521
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 142 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health