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Protein

Nuclear hormone receptor family member nhr-111

Gene

nhr-111

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Orphan nuclear receptor.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi39 – 11577Nuclear receptorPROSITE-ProRule annotationAdd
BLAST
Zinc fingeri42 – 6221NR C4-typePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri78 – 9821NR C4-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

SignaLinkiO45521.

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear hormone receptor family member nhr-111
Gene namesi
Name:nhr-111
ORF Names:F44G3.9
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF44G3.9; CE35538; WBGene00003701; nhr-111.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 311311Nuclear hormone receptor family member nhr-111PRO_0000223589Add
BLAST

Proteomic databases

PaxDbiO45521.

Expressioni

Gene expression databases

BgeeiWBGene00003701.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
gad-1O165193EBI-313236,EBI-327317
gst-19Q937013EBI-313236,EBI-321323
rpa-2Q95Y973EBI-313236,EBI-325404
ztf-4Q9TZI23EBI-313236,EBI-322494

Protein-protein interaction databases

BioGridi50516. 65 interactions.
DIPiDIP-26766N.
IntActiO45521. 99 interactions.
MINTiMINT-1037788.
STRINGi6239.F44G3.9.

Structurei

3D structure databases

ProteinModelPortaliO45521.
SMRiO45521. Positions 41-117.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.Curated
Contains 1 nuclear receptor DNA-binding domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri42 – 6221NR C4-typePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri78 – 9821NR C4-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00840000129707.
HOGENOMiHOG000260820.
InParanoidiO45521.
OMAiKACEIVI.
OrthoDBiEOG091G0AV3.
PhylomeDBiO45521.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O45521-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSQNAKSIG GILETSTVPL VIQPQIVNDP AQNNITLPIT LCAVCGDTSN
60 70 80 90 100
GNHYGVPTCF GCSGFFRRTV RNKLVHGCWN GDGNCVIDKA NRNRCKSCRI
110 120 130 140 150
KKCFKKGMNK NAVQPERTSH SYTVEYVELP SFREYSKGLL PTHSDRLRFQ
160 170 180 190 200
HEHAQHEIDT SSVLVHLKNA LQWVQQFSLF AVLSDVEKSQ IILTQWPHLL
210 220 230 240 250
CLALFENSEK IFIDEKFAQL AEKFKSLELS AQDYFLLKGI IIFTETKDGT
260 270 280 290 300
DLKFDRQLDI CIGLLNQLHL ESSKSKSGRL LFLLGELKSY STRQLESLLD
310
LKACEIVISF L
Length:311
Mass (Da):35,145
Last modified:July 5, 2004 - v2
Checksum:i3F54D39BA3732AA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83109 Genomic DNA. Translation: CAB05521.2.
PIRiT22203.
RefSeqiNP_507060.2. NM_074659.2.
UniGeneiCel.3575.

Genome annotation databases

EnsemblMetazoaiF44G3.9; F44G3.9; WBGene00003701.
GeneIDi185757.
KEGGicel:CELE_F44G3.9.
UCSCiF44G3.9. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83109 Genomic DNA. Translation: CAB05521.2.
PIRiT22203.
RefSeqiNP_507060.2. NM_074659.2.
UniGeneiCel.3575.

3D structure databases

ProteinModelPortaliO45521.
SMRiO45521. Positions 41-117.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi50516. 65 interactions.
DIPiDIP-26766N.
IntActiO45521. 99 interactions.
MINTiMINT-1037788.
STRINGi6239.F44G3.9.

Proteomic databases

PaxDbiO45521.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF44G3.9; F44G3.9; WBGene00003701.
GeneIDi185757.
KEGGicel:CELE_F44G3.9.
UCSCiF44G3.9. c. elegans.

Organism-specific databases

CTDi185757.
WormBaseiF44G3.9; CE35538; WBGene00003701; nhr-111.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00840000129707.
HOGENOMiHOG000260820.
InParanoidiO45521.
OMAiKACEIVI.
OrthoDBiEOG091G0AV3.
PhylomeDBiO45521.

Enzyme and pathway databases

SignaLinkiO45521.

Miscellaneous databases

PROiO45521.

Gene expression databases

BgeeiWBGene00003701.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNH111_CAEEL
AccessioniPrimary (citable) accession number: O45521
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 129 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.