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Protein
Submitted name:

DEgenerin Linked to Mechanosensation

Gene

delm-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Sodium channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Names & Taxonomyi

Protein namesi
Submitted name:
DEgenerin Linked to MechanosensationImported
Gene namesi
Name:delm-1Imported
ORF Names:CELE_F23B2.3Imported, F23B2.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiF23B2.3; CE35506; WBGene00009073; delm-1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei95 – 12026HelicalSequence analysisAdd
BLAST
Transmembranei507 – 53024HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiO45402.

Expressioni

Gene expression databases

BgeeiWBGene00009073.

Interactioni

Protein-protein interaction databases

STRINGi6239.F23B2.3.

Structurei

3D structure databases

ProteinModelPortaliO45402.
SMRiO45402. Positions 97-522.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiO45402.
OMAiWILSASY.
OrthoDBiEOG091G053J.
PhylomeDBiO45402.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.

Sequencei

Sequence statusi: Complete.

O45402-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSPPISPYH VDFRAGSSKE SLSPSTPSPM YPKCNFRYND SRTQMIIEVP
60 70 80 90 100
MAQLKKFQKA EGTISVKRET QHFCETTTMH GPKRIFKGKR IFTKLFWLIM
110 120 130 140 150
VLGSLGLLIY QCWILSASYL SKPIVSQVSF LIPEDGMEFP SVTVCNFTPI
160 170 180 190 200
RKSYIEAMNR TGDVSPDMIN YLMNWFTEIP ILLGNTDQQS LNKGNEELRE
210 220 230 240 250
YQSIHPNFTV DQFFMDASFD CSDLMKLCSF QGESFDCCSL ASPTLTPVGK
260 270 280 290 300
CFTLDLSKSP MNKQTEPGIR AGLSLTLDAN LDEQFDSSTG IDALLPNSFV
310 320 330 340 350
NGFRYFVHPK DTIPNLASDE YTVSPNSVAY SAISKFRYVL LPPNDWGNCT
360 370 380 390 400
EDYPYGIQSN LSYTSGNCLS LCKAKYFMNQ CGCTPALYNI GNNFQECTPF
410 420 430 440 450
ETYNCVNNSL SLLNEETGKM EFQPPSCTRC GQQCDSQVYR ADNSNGNQFS
460 470 480 490 500
AGAFNYFNSK NSSWSVDYMK SNFQMIRIFY RDMSYTEYNQ VQDASITDLL
510 520 530 540 550
SAIGGNMGMF LGGSVITIVE LFLFFSKVFW IGFSKTRRNY LYSKRANEKA
560 570 580 590 600
HKKEVVETVE KMKVIASQGN LTSLSDATCA TPPLKLSSPN KKVEFRINFE
610 620
DLASQLDFDS SECKGKSEKS SNLQKY
Length:626
Mass (Da):70,630
Last modified:July 5, 2004 - v2
Checksum:iC351416139FC0E41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAB05178.2.
PIRiT21296.
RefSeqiNP_501590.2. NM_069189.2.
UniGeneiCel.13086.

Genome annotation databases

EnsemblMetazoaiF23B2.3; F23B2.3; WBGene00009073.
GeneIDi184882.
KEGGicel:CELE_F23B2.3.
UCSCiF23B2.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAB05178.2.
PIRiT21296.
RefSeqiNP_501590.2. NM_069189.2.
UniGeneiCel.13086.

3D structure databases

ProteinModelPortaliO45402.
SMRiO45402. Positions 97-522.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F23B2.3.

Proteomic databases

PaxDbiO45402.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF23B2.3; F23B2.3; WBGene00009073.
GeneIDi184882.
KEGGicel:CELE_F23B2.3.
UCSCiF23B2.3. c. elegans.

Organism-specific databases

CTDi184882.
WormBaseiF23B2.3; CE35506; WBGene00009073; delm-1.

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiO45402.
OMAiWILSASY.
OrthoDBiEOG091G053J.
PhylomeDBiO45402.

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Gene expression databases

BgeeiWBGene00009073.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiO45402_CAEEL
AccessioniPrimary (citable) accession number: O45402
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 107 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.