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Protein
Submitted name:

Glutathione S-Transferase

Gene

gst-44

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • response to reactive oxygen species Source: WormBase
Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Enzyme and pathway databases

ReactomeiR-CEL-156581. Methylation.
R-CEL-156590. Glutathione conjugation.
R-CEL-196836. Vitamin C (ascorbate) metabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione S-TransferaseImported
Gene namesi
Name:gst-44Imported
ORF Names:CELE_F13A7.10Imported, F13A7.10Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF13A7.10; CE41223; WBGene00001792; gst-44.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiO45352.
PaxDbiO45352.

Interactioni

Protein-protein interaction databases

STRINGi6239.F13A7.10.

Structurei

3D structure databases

ProteinModelPortaliO45352.
SMRiO45352. Positions 8-254.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 10581GST N-terminalInterPro annotationAdd
BLAST
Domaini110 – 247138GST C-terminalInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the GST superfamily.UniRule annotationSAAS annotation
Contains GST C-terminal domain.SAAS annotation
Contains GST N-terminal domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG0406. Eukaryota.
ENOG410XSIX. LUCA.
GeneTreeiENSGT00390000005479.
HOGENOMiHOG000006560.
InParanoidiO45352.
KOiK00799.
OMAiNLTEKPD.
OrthoDBiEOG71CFNG.
PhylomeDBiO45352.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR005442. GST_omega.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
PRINTSiPR01625. GSTRNSFRASEO.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O45352-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVLEGINSK ALKTGDLPPP SPSPNTFRIY SMRFCPAAQR ALIYASVKKI
60 70 80 90 100
PSEVININLQ QKPDWYFTKN YKGQVPTLEH AEGKKLVIES AVIPEYLDDI
110 120 130 140 150
FPETKILPSD PYEKVQQKLL LERLSDQLTP AFGRVFRAIK NPEELKEKFE
160 170 180 190 200
SILKAFEEAE SLLEGAFYSG TSSPGFVDYL IYPSFQRVYW LTFLLEIFPL
210 220 230 240 250
PSDNFPGPGY PKLSQWFKAI TAIPEVAAAS QSTENGVGSC KEYMKGLPYF

DYGL
Length:254
Mass (Da):28,671
Last modified:July 10, 2007 - v2
Checksum:i61461F459A873ADF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAB07572.2.
PIRiT20806.
RefSeqiNP_507142.2. NM_074741.3.
UniGeneiCel.36681.

Genome annotation databases

EnsemblMetazoaiF13A7.10; F13A7.10; WBGene00001792.
GeneIDi184405.
KEGGicel:CELE_F13A7.10.
UCSCiF13A7.10. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAB07572.2.
PIRiT20806.
RefSeqiNP_507142.2. NM_074741.3.
UniGeneiCel.36681.

3D structure databases

ProteinModelPortaliO45352.
SMRiO45352. Positions 8-254.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F13A7.10.

Proteomic databases

EPDiO45352.
PaxDbiO45352.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF13A7.10; F13A7.10; WBGene00001792.
GeneIDi184405.
KEGGicel:CELE_F13A7.10.
UCSCiF13A7.10. c. elegans.

Organism-specific databases

CTDi184405.
WormBaseiF13A7.10; CE41223; WBGene00001792; gst-44.

Phylogenomic databases

eggNOGiKOG0406. Eukaryota.
ENOG410XSIX. LUCA.
GeneTreeiENSGT00390000005479.
HOGENOMiHOG000006560.
InParanoidiO45352.
KOiK00799.
OMAiNLTEKPD.
OrthoDBiEOG71CFNG.
PhylomeDBiO45352.

Enzyme and pathway databases

ReactomeiR-CEL-156581. Methylation.
R-CEL-156590. Glutathione conjugation.
R-CEL-196836. Vitamin C (ascorbate) metabolism.

Miscellaneous databases

NextBioi924620.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR005442. GST_omega.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
PRINTSiPR01625. GSTRNSFRASEO.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO45352_CAEEL
AccessioniPrimary (citable) accession number: O45352
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: July 10, 2007
Last modified: May 11, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.