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Protein
Submitted name:

CYtochrome P450 family

Gene

cyp-29a4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-CEL-211976. Endogenous sterols.
R-CEL-2453902. The canonical retinoid cycle in rods (twilight vision).

Names & Taxonomyi

Protein namesi
Submitted name:
CYtochrome P450 familyImported
Gene namesi
Name:cyp-29a4Imported
Synonyms:cyp-29A4Imported
ORF Names:B0331.1Imported, CELE_B0331.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiB0331.1; CE43023; WBGene00007140; cyp-29A4.

PTM / Processingi

Proteomic databases

PaxDbiO45219.
PRIDEiO45219.

Expressioni

Gene expression databases

BgeeiWBGene00007140.

Interactioni

Protein-protein interaction databases

STRINGi6239.B0331.1.

Structurei

3D structure databases

ProteinModelPortaliO45219.
SMRiO45219. Positions 34-501.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0157. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00760000118816.
HOGENOMiHOG000233834.
InParanoidiO45219.
KOiK17952.
OrthoDBiEOG091G06KN.
PhylomeDBiO45219.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O45219-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSILIPVALA LLFVYLLSFY DTIRLMRKFW IYGGKMPGPP AHPIFGNASL
60 70 80 90 100
FKNKTTKDFV ELFVQLAHEA RSKGANLMRT QVMNRIYVWP LNGKTAATIL
110 120 130 140 150
ESSTEVNKGD DYAFLVPWLG GGLLMEKGEK WKSHRRILTP AFHFAKLEGY
160 170 180 190 200
LDVFNSESKI LIDCLEKIAE TQETVDLFPF FKRCTLDIIC GTAMGIKLDA
210 220 230 240 250
QNVHNLGYVQ AVEGFNKLTV EYSLNPFLWN RFVYWALGYQ KMHDDFLYTL
260 270 280 290 300
KKFTNDAIVE RRTVIASGEI EKETSKRKMN FLDILLNSEE SNELTSDEIR
310 320 330 340 350
KEVDTFMFAG HDTTSTSLSW LCWNIAHNPE VQENVYKEII SIFGEDPNQD
360 370 380 390 400
VTSENINRLE YTERVLKESK RMFPPVPGFQ RKLTKDIVID GITIPSEGNI
410 420 430 440 450
TISPTVLHCN PFVYQNPEKF DPDRFLPEEC AKRHSYDYIP FSAGLRNCIG
460 470 480 490 500
QKFSILNEKV MLIHILRNFK LEPKLEFYET KPLFEVVAKP SHGIPVKLIK

RY
Length:502
Mass (Da):57,895
Last modified:November 4, 2008 - v2
Checksum:iFB5D82F2475FA6D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAB11775.2.
RefSeqiNP_505490.2. NM_073089.2.
UniGeneiCel.25609.

Genome annotation databases

EnsemblMetazoaiB0331.1; B0331.1; WBGene00007140.
GeneIDi181926.
KEGGicel:CELE_B0331.1.
UCSCiB0331.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAB11775.2.
RefSeqiNP_505490.2. NM_073089.2.
UniGeneiCel.25609.

3D structure databases

ProteinModelPortaliO45219.
SMRiO45219. Positions 34-501.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.B0331.1.

Proteomic databases

PaxDbiO45219.
PRIDEiO45219.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiB0331.1; B0331.1; WBGene00007140.
GeneIDi181926.
KEGGicel:CELE_B0331.1.
UCSCiB0331.1. c. elegans.

Organism-specific databases

CTDi181926.
WormBaseiB0331.1; CE43023; WBGene00007140; cyp-29A4.

Phylogenomic databases

eggNOGiKOG0157. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00760000118816.
HOGENOMiHOG000233834.
InParanoidiO45219.
KOiK17952.
OrthoDBiEOG091G06KN.
PhylomeDBiO45219.

Enzyme and pathway databases

ReactomeiR-CEL-211976. Endogenous sterols.
R-CEL-2453902. The canonical retinoid cycle in rods (twilight vision).

Gene expression databases

BgeeiWBGene00007140.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO45219_CAEEL
AccessioniPrimary (citable) accession number: O45219
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: November 4, 2008
Last modified: September 7, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.