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Protein
Submitted name:

SUPpressor

Gene

sup-12

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • pre-mRNA binding Source: WormBase
  • pre-mRNA intronic binding Source: WormBase
  • single-stranded RNA binding Source: WormBase

GO - Biological processi

  • alternative mRNA splicing, via spliceosome Source: WormBase
  • regulation of actin cytoskeleton organization Source: WormBase
  • regulation of alternative mRNA splicing, via spliceosome Source: WormBase
  • regulation of locomotion Source: WormBase

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
SUPpressorImported
Gene namesi
Name:sup-12Imported
ORF Names:CELE_T22B2.4Imported, T22B2.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiT22B2.4a; CE13934; WBGene00006321; sup-12.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

EPDiO45189.
PaxDbiO45189.

Expressioni

Gene expression databases

BgeeiWBGene00006321.
ExpressionAtlasiO45189. baseline and differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
asd-1G5EEW73EBI-312079,EBI-312085

Protein-protein interaction databases

DIPiDIP-24970N.
IntActiO45189. 5 interactors.
MINTiMINT-1047167.
STRINGi6239.T22B2.4a.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MGZNMR-B20-123[»]
2RU3NMR-A20-121[»]
4CH0NMR-S28-121[»]
4CIONMR-A28-121[»]
ProteinModelPortaliO45189.
SMRiO45189.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 112RRMInterPro annotationAdd BLAST78

Phylogenomic databases

eggNOGiKOG0149. Eukaryota.
ENOG4111PGT. LUCA.
GeneTreeiENSGT00390000002308.
HOGENOMiHOG000276232.
InParanoidiO45189.
OMAiTDRNTQK.
OrthoDBiEOG091G13K0.
PhylomeDBiO45189.

Family and domain databases

InterProiView protein in InterPro
IPR035979. RBD_domain_sf.
IPR000504. RRM_dom.
PfamiView protein in Pfam
PF00076. RRM_1. 1 hit.
SMARTiView protein in SMART
SM00360. RRM. 1 hit.
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 1 hit.

Sequencei

Sequence statusi: Complete.

O45189-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYGQVQDPLV HAAAAALAQS TNAEPVVGSR DTMFTKIFVG GLPYHTSDKT
60 70 80 90 100
LHEYFEQFGD IEEAVVITDR NTQKSRGYGF VTMKDRASAE RACKDPNPII
110 120 130 140 150
DGRKANVNLA YLGAKPRTNV QLAALAAGQV QLPLTTQLQA LFQPRMGLPQ
160 170 180 190 200
MYYPTVTGLV NPLMAQQGAA AQQQLFDYNA LAAVMNPQAA AAYGIQSQGK
210 220 230 240
FAAAPTTIEQ YAAYPAGYGL VPQSAYNIGN PQLQQLAAAQ QQLEHQRV
Length:248
Mass (Da):26,775
Last modified:June 1, 1998 - v1
Checksum:i93EB1C8B7EBF25F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CCD71425.1.
PIRiT33034.
RefSeqiNP_508674.1. NM_076273.4.
UniGeneiCel.4999.

Genome annotation databases

EnsemblMetazoaiT22B2.4a; T22B2.4a; WBGene00006321.
GeneIDi180674.
KEGGicel:CELE_T22B2.4.
UCSCiT22B2.4. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiO45189_CAEEL
AccessioniPrimary (citable) accession number: O45189
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: October 25, 2017
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported