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Protein

Serine/threonine-protein phosphatase

Gene

CELE_W03D8.2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
ORF Names:CELE_W03D8.2Imported, W03D8.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiW03D8.2b; CE18322; WBGene00020985.

PTM / Processingi

Proteomic databases

PaxDbiO45001.

Expressioni

Gene expression databases

BgeeiWBGene00020985.
ExpressionAtlasiO45001. differential.

Interactioni

Protein-protein interaction databases

IntActiO45001. 1 interactor.
STRINGi6239.W03D8.2b.

Structurei

3D structure databases

ProteinModelPortaliO45001.
SMRiO45001.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini139 – 144SER_THR_PHOSPHATASEInterPro annotation6

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiO45001.
OMAiPYGLACD.
OrthoDBiEOG091G0BOY.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O45001-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSNEKLPK INHDNEVFAL LYKILSSEVQ TIKGEDNEKV NQLRVDITIS
60 70 80 90 100
EISQLTDKMK KAFLEQPALL EISNEPITVV ADMHGQSIHL LRIFLTNEAP
110 120 130 140 150
PNQKYLFLGD YVDRGSQSVV VMCLLFCMKH RYPQHVFLLR GNHEDVNTTL
160 170 180 190 200
NYGFYDECLE QWKNDEGEKV WRMFIDTFNC MPLAAVIGGK VFCAHGGISP
210 220 230 240 250
WLESLEDINS IERPLVVPPY GLACDLLWSD PAQPERNGWG LSHRGISFTY
260 270 280 290 300
GKSVVEEFCA KNDIALVIRG HQLFKEMYPQ GCVLRFGGRL ISLFSALNYE
310 320 330 340 350
GHKNNSSVLK LEFVGQRVKV KQVLYRCRHY APLRSNEYLG FRDMKSSSGK
360
NEKRKKGRLE SLLG
Length:364
Mass (Da):41,570
Last modified:January 25, 2012 - v3
Checksum:i463BC73DE6227925
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD73386.1.
RefSeqiNP_001249242.1. NM_001262313.1.
UniGeneiCel.16619.

Genome annotation databases

EnsemblMetazoaiW03D8.2b; W03D8.2b; WBGene00020985.
GeneIDi171844.
KEGGicel:CELE_W03D8.2.
UCSCiW03D8.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD73386.1.
RefSeqiNP_001249242.1. NM_001262313.1.
UniGeneiCel.16619.

3D structure databases

ProteinModelPortaliO45001.
SMRiO45001.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO45001. 1 interactor.
STRINGi6239.W03D8.2b.

Proteomic databases

PaxDbiO45001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiW03D8.2b; W03D8.2b; WBGene00020985.
GeneIDi171844.
KEGGicel:CELE_W03D8.2.
UCSCiW03D8.2. c. elegans.

Organism-specific databases

CTDi171844.
WormBaseiW03D8.2b; CE18322; WBGene00020985.

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiO45001.
OMAiPYGLACD.
OrthoDBiEOG091G0BOY.

Gene expression databases

BgeeiWBGene00020985.
ExpressionAtlasiO45001. differential.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO45001_CAEEL
AccessioniPrimary (citable) accession number: O45001
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: January 25, 2012
Last modified: November 30, 2016
This is version 126 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.