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Protein
Submitted name:

PaTched Related family

Gene

ptr-11

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • molting cycle, collagen and cuticulin-based cuticle Source: WormBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PaTched Related familyImported
Gene namesi
Name:ptr-11Imported
ORF Names:CELE_F56C11.2Imported, F56C11.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF56C11.2a; CE17902; WBGene00004225; ptr-11.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 39HelicalSequence analysisAdd BLAST20
Transmembranei240 – 262HelicalSequence analysisAdd BLAST23
Transmembranei268 – 295HelicalSequence analysisAdd BLAST28
Transmembranei343 – 364HelicalSequence analysisAdd BLAST22
Transmembranei371 – 396HelicalSequence analysisAdd BLAST26
Transmembranei640 – 659HelicalSequence analysisAdd BLAST20
Transmembranei666 – 686HelicalSequence analysisAdd BLAST21
Transmembranei698 – 717HelicalSequence analysisAdd BLAST20
Transmembranei738 – 761HelicalSequence analysisAdd BLAST24
Transmembranei767 – 789HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiO44978.
PeptideAtlasiO44978.

Expressioni

Gene expression databases

BgeeiWBGene00004225.
ExpressionAtlasiO44978. differential.

Interactioni

Protein-protein interaction databases

STRINGi6239.F56C11.2.

Structurei

3D structure databases

ProteinModelPortaliO44978.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini240 – 397SSD (sterol-sensing)InterPro annotationAdd BLAST158

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1934. Eukaryota.
ENOG410XRZ4. LUCA.
GeneTreeiENSGT00800000124043.
HOGENOMiHOG000017687.
InParanoidiO44978.
OMAiAYPVYSI.
OrthoDBiEOG091G02AR.
PhylomeDBiO44978.

Family and domain databases

InterProiIPR003392. Ptc/Disp.
IPR000731. SSD.
[Graphical view]
PfamiPF02460. Patched. 1 hit.
[Graphical view]
PROSITEiPS50156. SSD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O44978-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGWDVISAVV ARLLAAYPVY SILLSILSIL VLSSGLVHIR LEPDIRKAFS
60 70 80 90 100
PDDSDAGYET RVWLEYYGLD IYPERAFCIF TAKRENSSIL QEGALADIYT
110 120 130 140 150
VDNRLSAAVG YQDGDGRKNC DPLCDLNSPF HLLANLTRRN NGTTSVFTYP
160 170 180 190 200
DMPYSGLDIF LGLHLSNADF EPPTERISSK SLVLWYFSRS DTPEGKLAFK
210 220 230 240 250
DAIDELFQLS KNSSAFEHVQ FTIFSDQVAN REMIRGAIEA TTLMTIGFFL
260 270 280 290 300
LLTQVIIVIV RLSSVKMAFY LVATSLLTPM AATVASFGAI CWMGFPSFSI
310 320 330 340 350
QCVTPFLVLG IGVDDAFILL HRWKHHIAIT DTPRRLEQVI VDVGPSITIT
360 370 380 390 400
SLTNIIAFGI GFLTPTPQMS LFCLTASLAL LLDYIFTYTI LAPIVFLCND
410 420 430 440 450
PDYKSIANET EPKISRADTW LSKYSSFVCS VKGRVACIMV LLGMYALTTY
460 470 480 490 500
GVVTMKTTFE PAKAFPSNSK LVDSLSNIKP VFNRYFPITV IVNNPPNIEI
510 520 530 540 550
KAEYDSFNNM MDRLEHVPGI RGDNRSLIFL PQYVNFDKTM NILSTLVGEK
560 570 580 590 600
YRPSYDNLPT WMDAIGNPPL VKYHMGDDNK TIVTAFRLTL LGKGMSEWAE
610 620 630 640 650
RARAMQHIRT ILHEESQFNA TLFDCDSAIL SIILTVGTDL IGSIAVTVVC
660 670 680 690 700
MAIVCFVFIA NFNAVAVITS VIASICYVLV GGLSLWGADL DPVIQVDVLL
710 720 730 740 750
ATGFSVDYTA HVAYNFFRAR GTPQERVYSS LAEMAMPMCE AGLSTFLCML
760 770 780 790 800
PLIFVPTYAI VCFAKTVFLV VAIGLLHGLF ILPVILALFS KDSINEKDNI
810 820
PAAITFSAAE PLVDKDLNAV
Length:820
Mass (Da):90,684
Last modified:June 1, 1998 - v1
Checksum:i2BB5AA9A205B4CB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD71715.1.
PIRiT32908.
RefSeqiNP_490687.1. NM_058286.4.
UniGeneiCel.6081.

Genome annotation databases

EnsemblMetazoaiF56C11.2a; F56C11.2a; WBGene00004225.
GeneIDi171609.
KEGGicel:CELE_F56C11.2.
UCSCiF56C11.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD71715.1.
PIRiT32908.
RefSeqiNP_490687.1. NM_058286.4.
UniGeneiCel.6081.

3D structure databases

ProteinModelPortaliO44978.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F56C11.2.

Proteomic databases

PaxDbiO44978.
PeptideAtlasiO44978.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF56C11.2a; F56C11.2a; WBGene00004225.
GeneIDi171609.
KEGGicel:CELE_F56C11.2.
UCSCiF56C11.2. c. elegans.

Organism-specific databases

CTDi171609.
WormBaseiF56C11.2a; CE17902; WBGene00004225; ptr-11.

Phylogenomic databases

eggNOGiKOG1934. Eukaryota.
ENOG410XRZ4. LUCA.
GeneTreeiENSGT00800000124043.
HOGENOMiHOG000017687.
InParanoidiO44978.
OMAiAYPVYSI.
OrthoDBiEOG091G02AR.
PhylomeDBiO44978.

Gene expression databases

BgeeiWBGene00004225.
ExpressionAtlasiO44978. differential.

Family and domain databases

InterProiIPR003392. Ptc/Disp.
IPR000731. SSD.
[Graphical view]
PfamiPF02460. Patched. 1 hit.
[Graphical view]
PROSITEiPS50156. SSD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO44978_CAEEL
AccessioniPrimary (citable) accession number: O44978
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: November 30, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.