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Protein
Submitted name:

Protein-tyrosine-phosphatase

Gene

CELE_ZK484.7

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphataseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protein-tyrosine-phosphataseImported
Gene namesi
ORF Names:CELE_ZK484.7Imported, ZK484.7Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiZK484.7; CE15349; WBGene00022753.

PTM / Processingi

Proteomic databases

PaxDbiO44901.
PRIDEiO44901.

Interactioni

Protein-protein interaction databases

STRINGi6239.ZK484.7.

Structurei

3D structure databases

ProteinModelPortaliO44901.
SMRiO44901. Positions 38-321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini55 – 317263Tyrosine-protein phosphataseInterPro annotationAdd
BLAST
Domaini237 – 30872TYR_PHOSPHATASE_2InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0789. Eukaryota.
COG5599. LUCA.
GeneTreeiENSGT00770000120452.
HOGENOMiHOG000017753.
InParanoidiO44901.
OMAiHLAFTEK.
OrthoDBiEOG7PGDVJ.
PhylomeDBiO44901.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O44901-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSVIQKRRT KKSTQKSKEV SQRTVDEGTT AEKKTHRKQI VKFVKNALEK
60 70 80 90 100
GPAGLRAEFA AMKRFNDFEK MKAFKEAQEH GKNRYKDVGC LDHNRVKLHP
110 120 130 140 150
PWPHDYIHAN FVSTPSNPRR FICTQAPLDK SCADFWYMCL QEKVDSIFML
160 170 180 190 200
CNIMEKGAKK CCDYFACKDK PVLEFEEKGH KIIVKFESTG KMKFEKNTDA
210 220 230 240 250
KITETVFTVE GPGGLAQKVT QYHWIDWPDR GVPTADMAIV ELLAKTRPSK
260 270 280 290 300
GPTVVHCSAG IGRTGSVVMI EYILDQLLGG QQIEETDKIL QKIREQRNNS
310 320 330 340
IQTDQQYLFV HQVILNYCLD KKMFDVDVKL AHLAFTEKYM KSVH
Length:344
Mass (Da):39,516
Last modified:June 1, 1998 - v1
Checksum:i98CACCCD11FA7A77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD65804.1.
PIRiT32869.
RefSeqiNP_491758.1. NM_059357.1.
UniGeneiCel.16139.

Genome annotation databases

EnsemblMetazoaiZK484.7; ZK484.7; WBGene00022753.
GeneIDi191327.
KEGGicel:CELE_ZK484.7.
UCSCiZK484.7. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD65804.1.
PIRiT32869.
RefSeqiNP_491758.1. NM_059357.1.
UniGeneiCel.16139.

3D structure databases

ProteinModelPortaliO44901.
SMRiO44901. Positions 38-321.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.ZK484.7.

Proteomic databases

PaxDbiO44901.
PRIDEiO44901.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZK484.7; ZK484.7; WBGene00022753.
GeneIDi191327.
KEGGicel:CELE_ZK484.7.
UCSCiZK484.7. c. elegans.

Organism-specific databases

CTDi191327.
WormBaseiZK484.7; CE15349; WBGene00022753.

Phylogenomic databases

eggNOGiKOG0789. Eukaryota.
COG5599. LUCA.
GeneTreeiENSGT00770000120452.
HOGENOMiHOG000017753.
InParanoidiO44901.
OMAiHLAFTEK.
OrthoDBiEOG7PGDVJ.
PhylomeDBiO44901.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO44901_CAEEL
AccessioniPrimary (citable) accession number: O44901
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: June 8, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.