ID   O44704_CAEEL            Unreviewed;       495 AA.
AC   O44704;
DT   01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 2.
DT   27-MAR-2024, entry version 167.
DE   SubName: Full=CYtochrome P450 family {ECO:0000313|EMBL:CCD67429.1};
GN   Name=cyp-33c1 {ECO:0000313|WormBase:C45H4.2};
GN   Synonyms=cyp-33C1 {ECO:0000313|EMBL:CCD67429.1};
GN   ORFNames=C45H4.2 {ECO:0000313|WormBase:C45H4.2}, CELE_C45H4.2
GN   {ECO:0000313|EMBL:CCD67429.1};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD67429.1, ECO:0000313|Proteomes:UP000001940};
RN   [1] {ECO:0000313|EMBL:CCD67429.1, ECO:0000313|Proteomes:UP000001940}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD67429.1,
RC   ECO:0000313|Proteomes:UP000001940};
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RA   Sulson J.E., Waterston R.;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; BX284605; CCD67429.1; -; Genomic_DNA.
DR   RefSeq; NP_503592.2; NM_071191.2.
DR   AlphaFoldDB; O44704; -.
DR   SMR; O44704; -.
DR   STRING; 6239.C45H4.2.1; -.
DR   EPD; O44704; -.
DR   PaxDb; 6239-C45H4-2; -.
DR   EnsemblMetazoa; C45H4.2.1; C45H4.2.1; WBGene00016686.
DR   GeneID; 183484; -.
DR   KEGG; cel:CELE_C45H4.2; -.
DR   UCSC; C45H4.2; c. elegans.
DR   AGR; WB:WBGene00016686; -.
DR   WormBase; C45H4.2; CE46272; WBGene00016686; cyp-33C1.
DR   eggNOG; KOG0156; Eukaryota.
DR   GeneTree; ENSGT00970000195868; -.
DR   HOGENOM; CLU_001570_22_0_1; -.
DR   InParanoid; O44704; -.
DR   OMA; HAFEWEC; -.
DR   OrthoDB; 2900138at2759; -.
DR   PhylomeDB; O44704; -.
DR   Reactome; R-CEL-211958; Miscellaneous substrates.
DR   Reactome; R-CEL-2142816; Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE).
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00016686; Expressed in material anatomical entity and 1 other cell type or tissue.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0020037; F:heme binding; IBA:GO_Central.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IBA:GO_Central.
DR   GO; GO:0008395; F:steroid hydroxylase activity; IBA:GO_Central.
DR   GO; GO:0006082; P:organic acid metabolic process; IBA:GO_Central.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IBA:GO_Central.
DR   CDD; cd20617; CYP1_2-like; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR   PANTHER; PTHR24300:SF196; CYTOCHROME P450 FAMILY; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW   ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001940}.
SQ   SEQUENCE   495 AA;  56725 MW;  056D9DDF95F5621C CRC64;
     MIIILLLTFL TIYFVYELYW KRRNFPPGPC PLPVFGNLLS IANPPPGYKA FERWTKKYGD
     VYTFWIGNTP HIMINTWDKI KETFIRDADT YTNKVVLPMV TLSRGGEYGI IDSNGAMWRE
     HRRFALSTMR DFGLGKNLMQ ENILMEVQDV FARLDAKLGS ETDVPEVFDH AVANVVNQLL
     FGYRFMGPKE NEYQELKHII DSPAEIFGKL HIFLAMNIPI FAKLLPESLY EGPIKTFRDT
     TLAFFNKQIE AHRHRIDFED LNSESTDFVE TFLKEQKRRE SEGDSETYSN IQLLNVCIDL
     WFAGLNTTTN TITWAISYVL HHPEVQDKIH EELDKVIGSD RLITTADKND LPYFNASINE
     SQRGINILPL NLQHATTRDT VIDGFKIPKG TGVVAQISTV MNNEEVFPDP YTFNPDRFID
     ENGKLKKVDE LAPFSVGKRS CPGEGLARME LFLFIANFLN RYKIHPSKEG LPSMAKGSGP
     VVAPRLFTAI LTRRF
//