cyp-34a7

Functionⁱ

GO - Molecular functionⁱ

heme binding Source: InterPro
iron ion binding Source: InterPro
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
steroid hydroxylase activity Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	MonooxygenaseUniRule annotation, Oxidoreductase
Ligand	HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: CYtochrome P450 familyImported
Gene namesⁱ	Name:cyp-34a7Imported Synonyms:cyp-34A7Imported ORF Names:B0213.12Imported, CELE_B0213.12Imported
Organismⁱ	Caenorhabditis elegansImported
Taxonomic identifierⁱ	6239 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis
Proteomesⁱ	UP000001940 Componentⁱ: Chromosome V

Organism-specific databases

WormBase More...WormBaseⁱ	B0213.12 ; CE16783 ; WBGene00015042 ; cyp-34A7

WormBaseⁱ

B0213.12 ; CE16783 ; WBGene00015042 ; cyp-34A7

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 15	Sequence analysisAdd BLAST		15
ChainⁱPRO_5012836317	16 – 499	Sequence analysisAdd BLAST		484

Proteomic databases

PaxDbⁱ	O44657
PeptideAtlas More...PeptideAtlasⁱ	O44657

Expressionⁱ

Gene expression databases

Bgeeⁱ	WBGene00015042

Bgeeⁱ

WBGene00015042

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	O44657 1 interactor.
STRINGⁱ	6239.B0213.12

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	O44657
SMRⁱ	O44657
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	192 – 212	Sequence analysisAdd BLAST		21

Sequence similaritiesⁱ

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domainⁱ

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0156 Eukaryota COG2124 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000144822
HOGENOMⁱ	HOG000036993
InParanoidⁱ	O44657
KEGG Orthology (KO) More...KOⁱ	K17956
OMAⁱ	FNDYWKE
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BT8
PhylomeDBⁱ	O44657

Family and domain databases

Gene3Dⁱ	1.10.630.101 hit
InterProⁱ	View protein in InterPro IPR001128 Cyt_P450 IPR017972 Cyt_P450_CS IPR002401 Cyt_P450_E_grp-I IPR036396 Cyt_P450_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00067 p450, 1 hit
PRINTSⁱ	PR00463 EP450I PR00385 P450
SUPFAMⁱ	SSF48264 SSF48264, 1 hit
PROSITEⁱ	View protein in PROSITE PS00086 CYTOCHROME_P450, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

O44657-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLIILILVAI AAVLTVNLWR ARQKLPNGPT PLPIIGNFHQ LFYNGWKYGG 
        60         70         80         90        100
LVAGFDQFRK QYGKVFTVWM GPIPAVQICD FDVAHETHVK KAHTFGHRYT 
       110        120        130        140        150
FGAMEYIREG KGIIGSNGDF WLEHRRFALM TLRNFGLGRN IIEDKIMEEY 
       160        170        180        190        200
RYRFEDFKKT NFKDGAIQVN ASSLFDLLVG SIINQLLVSE RFEQDDEEFE 
       210        220        230        240        250
ELKTNLAMAL ENGSIIEGVL PLWMLKSRFM KWRTKTTFAP FDFVFEVGKK 
       260        270        280        290        300
GIQRRVAAIE NGTHTLSEEG DDFVDAFIVK MEKDKKDGID SSFTLETLAV 
       310        320        330        340        350
DLFDLWQAGQ ETTSTTLTWA CACLLNHPEV VEKLRKELTE VTGGARGVSL 
       360        370        380        390        400
TDRTKTPYLN ATINEVQRIS SILNVNLLRI LEEDAVIDGH PVPAGTAFTT 
       410        420        430        440        450
QLALLHTDEE TFKNHKEFIP ERFLENNNLE KRLIPFGIGK RSCPGESLAK 
       460        470        480        490 
AELYLIIGNL VIDFDLKPVG AIPKIESPTP FSPVKRPPVY DIRFISRAH

Length:499

Mass (Da):56,619

Last modified:June 1, 1998 - v1

Checksum:ⁱ8BE6AC963FAD0357

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX284605 Genomic DNA Translation: CCD61362.1
PIRⁱ	C89015
NCBI Reference Sequences More...RefSeqⁱ	NP_504101.1, NM_071700.1
UniGeneⁱ	Cel.9462

Genome annotation databases

EnsemblMetazoaⁱ	B0213.12; B0213.12; WBGene00015042
GeneIDⁱ	181849
KEGGⁱ	cel:CELE_B0213.12
UCSC genome browser More...UCSCⁱ	B0213.12 c. elegans

Similar proteinsⁱ

50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
O44657	A8WQ02 A0A1I7TXU2 G0NHN9 E3LHE8 A0A2H2HX81 A8WQ04 A0A2G5TB18 UPI0000223187 O44655 E3LHE7 +30	Caenorhabditis briggsae Caenorhabditis tropicalis Caenorhabditis brenneri (Nematode worm) Caenorhabditis remanei (Caenorhabditis vulgaris) Caenorhabditis japonica Caenorhabditis nigoni Caenorhabditis elegans	499	UniRef50_O44657	Cluster: CYtochrome P450 family	41

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX284605 Genomic DNA Translation: CCD61362.1
PIRⁱ	C89015
NCBI Reference Sequences More...RefSeqⁱ	NP_504101.1, NM_071700.1
UniGeneⁱ	Cel.9462

3D structure databases

ProteinModelPortalⁱ	O44657
SMRⁱ	O44657
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	O44657 1 interactor.
STRINGⁱ	6239.B0213.12

Proteomic databases

PaxDbⁱ	O44657
PeptideAtlas More...PeptideAtlasⁱ	O44657

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblMetazoaⁱ	B0213.12; B0213.12; WBGene00015042
GeneIDⁱ	181849
KEGGⁱ	cel:CELE_B0213.12
UCSC genome browser More...UCSCⁱ	B0213.12 c. elegans

Organism-specific databases

CTDⁱ	181849
WormBase More...WormBaseⁱ	B0213.12 ; CE16783 ; WBGene00015042 ; cyp-34A7

Phylogenomic databases

eggNOGⁱ	KOG0156 Eukaryota COG2124 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000144822
HOGENOMⁱ	HOG000036993
InParanoidⁱ	O44657
KEGG Orthology (KO) More...KOⁱ	K17956
OMAⁱ	FNDYWKE
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BT8
PhylomeDBⁱ	O44657

Gene expression databases

Bgeeⁱ	WBGene00015042

Bgeeⁱ

WBGene00015042

Family and domain databases

Gene3Dⁱ	1.10.630.101 hit
InterProⁱ	View protein in InterPro IPR001128 Cyt_P450 IPR017972 Cyt_P450_CS IPR002401 Cyt_P450_E_grp-I IPR036396 Cyt_P450_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00067 p450, 1 hit
PRINTSⁱ	PR00463 EP450I PR00385 P450
SUPFAMⁱ	SSF48264 SSF48264, 1 hit
PROSITEⁱ	View protein in PROSITE PS00086 CYTOCHROME_P450, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	O44657_CAEEL
Accessionⁱ	O44657Primary (citable) accession number: O44657
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	June 1, 1998
	Last sequence update:	June 1, 1998
	Last modified:	March 28, 2018
	This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O44657 (O44657_CAEEL)

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CYtochrome P450 family

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

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Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

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Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ