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Protein

Facilitated glucose transporter homolog

Gene

R09B5.11

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Appears to have no transport activity for glucose.1 Publication

GO - Molecular functioni

Keywordsi

Biological processTransport

Enzyme and pathway databases

ReactomeiR-CEL-189200 Cellular hexose transport
R-CEL-196836 Vitamin C (ascorbate) metabolism
R-CEL-422356 Regulation of insulin secretion
R-CEL-5653890 Lactose synthesis
R-CEL-6798695 Neutrophil degranulation
R-CEL-8981373 Intestinal hexose absorption

Names & Taxonomyi

Protein namesi
Recommended name:
Facilitated glucose transporter homolog1 Publication
Gene namesi
ORF Names:R09B5.11
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiR09B5.11 ; CE30296 ; WBGene00019979

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 47CytoplasmicSequence analysisAdd BLAST47
Transmembranei48 – 68Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini69 – 101ExtracellularSequence analysisAdd BLAST33
Transmembranei102 – 122Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini123 – 138CytoplasmicSequence analysisAdd BLAST16
Transmembranei139 – 159Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini160 – 161ExtracellularSequence analysis2
Transmembranei162 – 182Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini183 – 200CytoplasmicSequence analysisAdd BLAST18
Transmembranei201 – 221Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini222ExtracellularSequence analysis1
Transmembranei223 – 243Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini244 – 306CytoplasmicSequence analysisAdd BLAST63
Transmembranei307 – 327Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini328 – 344ExtracellularSequence analysisAdd BLAST17
Transmembranei345 – 365Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini366 – 376CytoplasmicSequence analysisAdd BLAST11
Transmembranei377 – 397Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini398 – 409ExtracellularSequence analysisAdd BLAST12
Transmembranei410 – 430Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini431 – 444CytoplasmicSequence analysisAdd BLAST14
Transmembranei445 – 465Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini466 – 471ExtracellularSequence analysis6
Transmembranei472 – 492Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini493 – 516CytoplasmicSequence analysisAdd BLAST24

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004251471 – 516Facilitated glucose transporter homologAdd BLAST516

Proteomic databases

EPDiO44616
PaxDbiO44616

Expressioni

Tissue specificityi

Expressed in seam cells from the early embryonic stage through the L2 stage (at protein level).1 Publication

Gene expression databases

BgeeiWBGene00019979

Interactioni

Protein-protein interaction databases

STRINGi6239.R09B5.11

Structurei

3D structure databases

ProteinModelPortaliO44616
SMRiO44616
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0569 Eukaryota
COG0477 LUCA
GeneTreeiENSGT00760000119022
HOGENOMiHOG000202871
InParanoidiO44616
KOiK07299
OMAiKMVVIFQ
OrthoDBiEOG091G0A9K
PhylomeDBiO44616

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit

Sequencei

Sequence statusi: Complete.

O44616-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAVVASQNK NDRSFSNMES ESSSNVEKSE KENHHQSLPD ENWTPFLFFC
60 70 80 90 100
ISSIALASFQ DGFQIGCINA PGPLIIDWIK KCHFELFGEV LSQYQADFIW
110 120 130 140 150
SVAVSMFSVG GMFGSFCSGF LADKFGRKST LLYNNILALL AAVCLSTSKL
160 170 180 190 200
FNFYPMIVFG RFLVGLNCGI TSGLVPMFLT ELAPANLRGK CGSFHQLNIS
210 220 230 240 250
VAIVLSQALG LPQIFGTQVG WPYIFACVAI PTFLQLATIP FCVESPKYLI
260 270 280 290 300
SKLNDREEAR RILEKLRGHT KVDEELEHMV QETMVTVEPL HQPGYVSLFK
310 320 330 340 350
GDNQWPMIVS ILMMFSQQFS GISAVTFYST LIFKRNGLSG NEPMYATVGF
360 370 380 390 400
GCIKLIATFG CLFLIDHPKF GRKRLHIAGL SGMCISSILI VITLTLSNAG
410 420 430 440 450
YHWASYMNVL FILSFVVTFA FGPGPIPWFF TSELFDSATR GRAAAVSATS
460 470 480 490 500
NWVANWMVGL TFLPINNIIH QYAFLMFTFF TFTFAIFTWK FVPETKGKSP
510
SAIRKELAFM RKRICS
Length:516
Mass (Da):57,609
Last modified:March 1, 2002 - v2
Checksum:i4152B72150088C9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081061 Genomic DNA Translation: CCD68888.1
PIRiC88950
RefSeqiNP_503413.2, NM_071012.5
UniGeneiCel.7764

Genome annotation databases

EnsemblMetazoaiR09B5.11.1; R09B5.11.1; WBGene00019979
R09B5.11.2; R09B5.11.2; WBGene00019979
GeneIDi178634
KEGGicel:CELE_R09B5.11
UCSCiR09B5.11 c. elegans

Similar proteinsi

Entry informationi

Entry nameiFGTH1_CAEEL
AccessioniPrimary (citable) accession number: O44616
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 22, 2014
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 136 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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