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Protein
Submitted name:

Nuclear Hormone Receptor family

Gene

nhr-256

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi3 – 79Nuclear receptorPROSITE-ProRule annotationAdd BLAST77

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear Hormone Receptor familyImported
Gene namesi
Name:nhr-256Imported
ORF Names:CELE_ZK697.2Imported, ZK697.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiZK697.2a ; CE15397 ; WBGene00022805 ; nhr-256

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiO44577

Expressioni

Gene expression databases

BgeeiWBGene00022805
ExpressionAtlasiO44577 baseline and differential

Interactioni

Protein-protein interaction databases

DIPiDIP-27064N
IntActiO44577, 3 interactors
STRINGi6239.ZK697.2

Structurei

3D structure databases

ProteinModelPortaliO44577
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 79Nuclear receptorInterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00910000144774
HOGENOMiHOG000113781
InParanoidiO44577
OMAiMIRRQWK
OrthoDBiEOG091G099Y
PhylomeDBiO44577

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

O44577-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRGNCKVCD SPNATNFHFG AHSCKACAAF FRRTVKTGQI YSCPGEKTCE
60 70 80 90 100
INHVFRQNCR QCRLAKCLKA GMQEELVQGH KMNGENKRSS PVDVIASTSD
110 120 130 140 150
YYDPLQFPIQ STSQSSESYY PPAKSMKIDD DLMEIEELQH FIKIPNEPSL
160 170 180 190 200
AVSPPIDVME EEDRLYKLAT LYIEQFVNLN MRRRLTYANV SLSAMFDNPC
210 220 230 240 250
VCPFDLSDMK PLSYDTYRYK NRNDYTMILD YVNRFPEFHL LNKSEKTVLF
260 270 280 290 300
QTTAAVDALA DPAYYSQVIY PDEPVFVTRE AKYLKMDPMP STELEVVPQD
310 320 330 340 350
CNLEDITIYK NVVLMIRRQW KNVNEPLRKL KLSLAEFSLF KALAIWHYNY
360 370 380 390 400
YKLQNTGRQI SARQRDDIFR TLLLICEDEG YDDPILRVSE IVLAVGIVMS
410 420 430
EVHELVTTMF EITVFANVDD PILKDMLKFQ Y
Length:431
Mass (Da):49,904
Last modified:June 1, 1998 - v1
Checksum:i91DA173E6305514A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD74363.1
PIRiC88957
RefSeqiNP_503495.1, NM_071094.1
UniGeneiCel.1279

Genome annotation databases

EnsemblMetazoaiZK697.2a; ZK697.2a; WBGene00022805
GeneIDi191409
KEGGicel:CELE_ZK697.2
UCSCiZK697.2 c. elegans

Similar proteinsi

Entry informationi

Entry nameiO44577_CAEEL
AccessioniPrimary (citable) accession number: O44577
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 148 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health