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Protein
Submitted name:

Nuclear Hormone Receptor family

Gene

nhr-256

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorUniRule annotationImported

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear Hormone Receptor familyImported
Gene namesi
Name:nhr-256Imported
ORF Names:CELE_ZK697.2Imported, ZK697.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiZK697.2a; CE15397; WBGene00022805; nhr-256.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiO44577.

Interactioni

Protein-protein interaction databases

DIPiDIP-27064N.
IntActiO44577. 3 interactions.
MINTiMINT-1075669.
STRINGi6239.ZK697.2.

Structurei

3D structure databases

ProteinModelPortaliO44577.
SMRiO44577. Positions 6-104.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 7977Nuclear receptor DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation
Contains nuclear receptor DNA-binding domain.SAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOGENOMiHOG000113781.
InParanoidiO44577.
OMAiGRQISAR.
OrthoDBiEOG77Q51K.
PhylomeDBiO44577.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O44577-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRGNCKVCD SPNATNFHFG AHSCKACAAF FRRTVKTGQI YSCPGEKTCE
60 70 80 90 100
INHVFRQNCR QCRLAKCLKA GMQEELVQGH KMNGENKRSS PVDVIASTSD
110 120 130 140 150
YYDPLQFPIQ STSQSSESYY PPAKSMKIDD DLMEIEELQH FIKIPNEPSL
160 170 180 190 200
AVSPPIDVME EEDRLYKLAT LYIEQFVNLN MRRRLTYANV SLSAMFDNPC
210 220 230 240 250
VCPFDLSDMK PLSYDTYRYK NRNDYTMILD YVNRFPEFHL LNKSEKTVLF
260 270 280 290 300
QTTAAVDALA DPAYYSQVIY PDEPVFVTRE AKYLKMDPMP STELEVVPQD
310 320 330 340 350
CNLEDITIYK NVVLMIRRQW KNVNEPLRKL KLSLAEFSLF KALAIWHYNY
360 370 380 390 400
YKLQNTGRQI SARQRDDIFR TLLLICEDEG YDDPILRVSE IVLAVGIVMS
410 420 430
EVHELVTTMF EITVFANVDD PILKDMLKFQ Y
Length:431
Mass (Da):49,904
Last modified:June 1, 1998 - v1
Checksum:i91DA173E6305514A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD74363.1.
PIRiC88957.
RefSeqiNP_503495.1. NM_071094.1.
UniGeneiCel.1279.

Genome annotation databases

EnsemblMetazoaiZK697.2; ZK697.2; WBGene00022805.
ZK697.2a; ZK697.2a; WBGene00022805.
GeneIDi191409.
KEGGicel:CELE_ZK697.2.
UCSCiZK697.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD74363.1.
PIRiC88957.
RefSeqiNP_503495.1. NM_071094.1.
UniGeneiCel.1279.

3D structure databases

ProteinModelPortaliO44577.
SMRiO44577. Positions 6-104.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-27064N.
IntActiO44577. 3 interactions.
MINTiMINT-1075669.
STRINGi6239.ZK697.2.

Proteomic databases

PaxDbiO44577.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZK697.2; ZK697.2; WBGene00022805.
ZK697.2a; ZK697.2a; WBGene00022805.
GeneIDi191409.
KEGGicel:CELE_ZK697.2.
UCSCiZK697.2. c. elegans.

Organism-specific databases

CTDi191409.
WormBaseiZK697.2a; CE15397; WBGene00022805; nhr-256.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOGENOMiHOG000113781.
InParanoidiO44577.
OMAiGRQISAR.
OrthoDBiEOG77Q51K.
PhylomeDBiO44577.

Miscellaneous databases

NextBioi949056.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO44577_CAEEL
AccessioniPrimary (citable) accession number: O44577
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: May 11, 2016
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.