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Protein

Serine/threonine-protein phosphatase

Gene

CELE_F42G8.8

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphoprotein phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
ORF Names:CELE_F42G8.8Imported, F42G8.8Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiF42G8.8; CE49561; WBGene00018359.

PTM / Processingi

Proteomic databases

PaxDbiO44507.
PRIDEiO44507.

Interactioni

Protein-protein interaction databases

STRINGi6239.F42G8.8.

Structurei

3D structure databases

ProteinModelPortaliO44507.
SMRiO44507. Positions 52-311.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0639.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiO44507.
OrthoDBiEOG7V76BC.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O44507-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADDKSFDVN MFLKRHLIVK SWANYRQLEY TKSELIQLID LVTPALKEDN
60 70 80 90 100
SLAQISPPVT IVGDIHGQFH DLIRILNYNV PKDDAKKKSG YGFCNNRFVF
110 120 130 140 150
LGDYVDRGSH SIECISLMFA LKIIYQTNYI LLRGNHETRA INYAYGFREE
160 170 180 190 200
LVNRLGPADG KEVWEKFNEV FAYMPLACLV GEKILCMHGG ISPRLNTLED
210 220 230 240 250
IKNIDHPLFE IGNDSLAQDL LWADPTDGQG LIAVSQTPAY PKNIVRGLSV
260 270 280 290 300
VFNEAAVHDT CKRLGIKLIV RAHQMIPEGF KFFADQKLLT IFSAPRYMNE
310 320 330 340 350
TDNHGATLKV ETNGRLSIGR LRNMKALHPN VAADEITRGD DMPSGAKVAK
360 370 380
KKSNSMTVSA SKSSSSSNSH GKGKNKSGSI GTL
Length:383
Mass (Da):42,677
Last modified:April 16, 2014 - v2
Checksum:i1F07E10D75837745
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD61407.2.
PIRiT32635.
UniGeneiCel.26809.

Genome annotation databases

EnsemblMetazoaiF42G8.8; F42G8.8; WBGene00018359.
UCSCiF42G8.8. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD61407.2.
PIRiT32635.
UniGeneiCel.26809.

3D structure databases

ProteinModelPortaliO44507.
SMRiO44507. Positions 52-311.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F42G8.8.

Proteomic databases

PaxDbiO44507.
PRIDEiO44507.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF42G8.8; F42G8.8; WBGene00018359.
UCSCiF42G8.8. c. elegans.

Organism-specific databases

WormBaseiF42G8.8; CE49561; WBGene00018359.

Phylogenomic databases

eggNOGiCOG0639.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiO44507.
OrthoDBiEOG7V76BC.

Miscellaneous databases

NextBioi929104.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO44507_CAEEL
AccessioniPrimary (citable) accession number: O44507
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: April 16, 2014
Last modified: April 1, 2015
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.