ID   T17B1_CAEEL             Reviewed;         181 AA.
AC   O44477;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   27-MAR-2024, entry version 136.
DE   RecName: Full=Probable mitochondrial import inner membrane translocase subunit tim-17B.1 {ECO:0000305};
GN   Name=timm-17B.1 {ECO:0000312|WormBase:E04A4.5};
GN   Synonyms=tim-17 {ECO:0000312|WormBase:E04A4.5}, timm-17
GN   {ECO:0000312|WormBase:E04A4.5};
GN   ORFNames=E04A4.5 {ECO:0000312|WormBase:E04A4.5};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Essential component of the TIM23 complex, a complex that
CC       mediates the translocation of transit peptide-containing proteins
CC       across the mitochondrial inner membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Tim17/Tim22/Tim23 family. {ECO:0000305}.
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DR   EMBL; FO081039; CCD68707.1; -; Genomic_DNA.
DR   PIR; T32609; T32609.
DR   RefSeq; NP_500627.1; NM_068226.5.
DR   AlphaFoldDB; O44477; -.
DR   SMR; O44477; -.
DR   BioGRID; 42371; 4.
DR   STRING; 6239.E04A4.5.1; -.
DR   EPD; O44477; -.
DR   PaxDb; 6239-E04A4-5; -.
DR   PeptideAtlas; O44477; -.
DR   EnsemblMetazoa; E04A4.5.1; E04A4.5.1; WBGene00017119.
DR   GeneID; 177242; -.
DR   KEGG; cel:CELE_E04A4.5; -.
DR   UCSC; E04A4.5; c. elegans.
DR   AGR; WB:WBGene00017119; -.
DR   WormBase; E04A4.5; CE16966; WBGene00017119; timm-17B.1.
DR   eggNOG; KOG1652; Eukaryota.
DR   GeneTree; ENSGT00390000017780; -.
DR   HOGENOM; CLU_087811_1_1_1; -.
DR   InParanoid; O44477; -.
DR   OMA; CPWVILS; -.
DR   OrthoDB; 179242at2759; -.
DR   PhylomeDB; O44477; -.
DR   PRO; PR:O44477; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00017119; Expressed in pharyngeal muscle cell (C elegans) and 3 other cell types or tissues.
DR   GO; GO:0005744; C:TIM23 mitochondrial import inner membrane translocase complex; IBA:GO_Central.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR   InterPro; IPR005678; Tim17.
DR   NCBIfam; TIGR00980; 3a0801so1tim17; 1.
DR   PANTHER; PTHR10485:SF0; AT05822P-RELATED; 1.
DR   PANTHER; PTHR10485; MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17; 1.
DR   Pfam; PF02466; Tim17; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW   Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..181
FT                   /note="Probable mitochondrial import inner membrane
FT                   translocase subunit tim-17B.1"
FT                   /id="PRO_0000210289"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          137..181
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   181 AA;  19096 MW;  505D8F8CB2BBE9DB CRC64;
     MEEYTREPCP YRIGDDIGSA FAMGLVGGSI FQAFGGYKNA AKGKKLVGMM REVRMRSTLT
     GVQFAAWGGM FSTIDCCLVA IRKKEDPINS IVSGGLTGAL LAIRSGPKVM AGSAILGSVI
     LAMIEGVGLV TTRWMGAMMD PTQPPPEALD DPRSLGQKSQ AEPGLDQTRP FGIPTGLPNL
     S
//