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O44477 (TIM17_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable mitochondrial import inner membrane translocase subunit Tim17
Gene names
Name:tim-17
ORF Names:E04A4.5
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length181 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane By similarity.

Subunit structure

Component of the TIM23 complex at least composed of tim-23, tim-17 and tim-50. The complex interacts with the tim-44 component of the PAM complex By similarity.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the Tim17/Tim22/Tim23 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 181181Probable mitochondrial import inner membrane translocase subunit Tim17
PRO_0000210289

Regions

Transmembrane17 – 3721Helical; Potential
Transmembrane61 – 8121Helical; Potential
Transmembrane109 – 12921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O44477 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 505D8F8CB2BBE9DB

FASTA18119,096
        10         20         30         40         50         60 
MEEYTREPCP YRIGDDIGSA FAMGLVGGSI FQAFGGYKNA AKGKKLVGMM REVRMRSTLT 

        70         80         90        100        110        120 
GVQFAAWGGM FSTIDCCLVA IRKKEDPINS IVSGGLTGAL LAIRSGPKVM AGSAILGSVI 

       130        140        150        160        170        180 
LAMIEGVGLV TTRWMGAMMD PTQPPPEALD DPRSLGQKSQ AEPGLDQTRP FGIPTGLPNL 


S 

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References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FO081039 Genomic DNA. Translation: CCD68707.1.
PIRT32609.
RefSeqNP_500627.1. NM_068226.5.
UniGeneCel.6756.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.E04A4.5.

Proteomic databases

PaxDbO44477.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaE04A4.5.1; E04A4.5.1; E04A4.5.
E04A4.5.2; E04A4.5.2; E04A4.5.
GeneID177242.
KEGGcel:CELE_E04A4.5.
UCSCE04A4.5. c. elegans.

Organism-specific databases

CTD177242.
WormBaseE04A4.5; CE16966; WBGene00017119.

Phylogenomic databases

eggNOGCOG5596.
HOGENOMHOG000183190.
InParanoidO44477.
KOK17795.
OMAWKHTRNS.
PhylomeDBO44477.

Family and domain databases

InterProIPR005678. Tim17.
IPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PfamPF02466. Tim17. 1 hit.
[Graphical view]
TIGRFAMsTIGR00980. 3a0801so1tim17. 1 hit.
ProtoNetSearch...

Other

NextBio895950.
PROO44477.

Entry information

Entry nameTIM17_CAEEL
AccessionPrimary (citable) accession number: O44477
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: June 1, 1998
Last modified: April 16, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase