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Protein
Submitted name:

Ligand-Gated ion Channel

Gene

lgc-9

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelUniRule annotation
Biological processIon transport, Transport

Enzyme and pathway databases

ReactomeiR-CEL-975298. Ligand-gated ion channel transport.

Names & Taxonomyi

Protein namesi
Submitted name:
Ligand-Gated ion ChannelImported
Gene namesi
Name:lgc-9Imported
ORF Names:C04C3.2Imported, CELE_C04C3.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC04C3.2; CE29558; WBGene00015412; lgc-9.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei247 – 269HelicalSequence analysisAdd BLAST23
Transmembranei281 – 301HelicalSequence analysisAdd BLAST21
Transmembranei313 – 335HelicalSequence analysisAdd BLAST23
Transmembranei430 – 455HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiO44452.

Expressioni

Gene expression databases

BgeeiWBGene00015412.

Interactioni

Protein-protein interaction databases

DIPiDIP-25695N.
IntActiO44452. 1 interactor.
MINTiMINT-1129182.
STRINGi6239.C04C3.2.

Structurei

3D structure databases

ProteinModelPortaliO44452.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 245Neur_chan_LBDInterPro annotationAdd BLAST204
Domaini252 – 347Neur_chan_membInterPro annotationAdd BLAST96

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3645. Eukaryota.
ENOG410XQGR. LUCA.
GeneTreeiENSGT00790000122957.
HOGENOMiHOG000017780.
InParanoidiO44452.
OMAiHRVEIEW.
OrthoDBiEOG091G06O1.
PhylomeDBiO44452.

Family and domain databases

Gene3Di2.70.170.10. 1 hit.
InterProiView protein in InterPro
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiView protein in Pfam
PF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
PRINTSiPR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
PROSITEiView protein in PROSITE
PS00236. NEUROTR_ION_CHANNEL. 1 hit.

Sequencei

Sequence statusi: Complete.

O44452-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYFIQLLSVL ISMKVGHIRS SRLLQHSQHG HYEDDYIKTE PTHLIETIQR
60 70 80 90 100
RYDKRVRPFA ESNRPVIVHM TIVLGILTEV RENQQVASFV ISHVQKWRDP
110 120 130 140 150
KLAWNPADHS GLTQVVMPRS LVWVPKLFIY NSMDTKDMLT DDRYDVRIQH
160 170 180 190 200
TGHVKVNSPQ FVSTLCRINI DLFPFDTQFC AIALASPLLS VEEMDVNATQ
210 220 230 240 250
PPVDSYFSGN AEWQVMNVTV KQMKFMEEGE YRAEVHYILH LNRRPTYYIT
260 270 280 290 300
VIVVPTFLIS ALSILGIFSP GSNDGPRNEK VSLGLGSLLA MTVLLDIVAG
310 320 330 340 350
AMPKSDAIPL LGYYIMLVIL LCAIGVAVSM AMLSMSRSCI QTSKMPPPHY
360 370 380 390 400
YRLLFLNVCR VVKQNSGLNG VAMNEKPTAI TPRFPDLIAI YNQLIEVARA
410 420 430 440 450
QRTYRERIEK QKWQHRVEIE WNKIFARIDF FFLFLFEMFN VLILVLFLRC
460
AFLPVPPLPE NFSI
Length:464
Mass (Da):53,308
Last modified:December 1, 2001 - v2
Checksum:iDC47B9961960FA4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD62195.1.
PIRiT32599.
RefSeqiNP_500341.1. NM_067940.4.
UniGeneiCel.13608.

Genome annotation databases

EnsemblMetazoaiC04C3.2; C04C3.2; WBGene00015412.
GeneIDi182195.
KEGGicel:CELE_C04C3.2.
UCSCiC04C3.2. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiO44452_CAEEL
AccessioniPrimary (citable) accession number: O44452
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: December 1, 2001
Last modified: August 30, 2017
This is version 133 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported