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Protein
Submitted name:

Putative porin

Gene

TT95

Organism
Trichuris trichiura (Whipworm) (Trichocephalus trichiurus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

MEROPSiI17.003.
TCDBi1.C.15.1.1. the whipworm stichosome porin (wsp) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative porinImported
Gene namesi
Name:TT95Imported
OrganismiTrichuris trichiura (Whipworm) (Trichocephalus trichiurus)Imported
Taxonomic identifieri36087 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaEnopleaDorylaimiaTrichocephalidaTrichuridaeTrichuris

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 903879Sequence analysisPRO_5004159068Add
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 6846WAPInterPro annotationAdd
BLAST
Domaini99 – 14446WAPInterPro annotationAdd
BLAST
Domaini149 – 19547WAPInterPro annotationAdd
BLAST
Domaini200 – 24546WAPInterPro annotationAdd
BLAST
Domaini250 – 29647WAPInterPro annotationAdd
BLAST
Domaini301 – 34646WAPInterPro annotationAdd
BLAST
Domaini351 – 39747WAPInterPro annotationAdd
BLAST
Domaini402 – 44746WAPInterPro annotationAdd
BLAST
Domaini452 – 49847WAPInterPro annotationAdd
BLAST
Domaini503 – 54846WAPInterPro annotationAdd
BLAST
Domaini553 – 59947WAPInterPro annotationAdd
BLAST
Domaini604 – 64946WAPInterPro annotationAdd
BLAST
Domaini654 – 70047WAPInterPro annotationAdd
BLAST
Domaini705 – 75046WAPInterPro annotationAdd
BLAST
Domaini755 – 80147WAPInterPro annotationAdd
BLAST
Domaini806 – 85146WAPInterPro annotationAdd
BLAST
Domaini856 – 90045WAPInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di4.10.75.10. 17 hits.
InterProiIPR008197. WAP_dom.
[Graphical view]
PfamiPF00095. WAP. 17 hits.
[Graphical view]
SMARTiSM00217. WAP. 17 hits.
[Graphical view]
SUPFAMiSSF57256. SSF57256. 17 hits.
PROSITEiPS51390. WAP. 17 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O44397-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAPGPLLIG LAICLLQGIQ DAESAKMGRC PPPSFGAGRA RFCYTDRQCP
60 70 80 90 100
GRMKCCLTKR GYACTAPDIS YPGPLKPTWN NPKCDEHGDC SKPKPQPADK
110 120 130 140 150
QKPGTCPPSN MFTGTAPFCD TDSDCKGIEK CCLTKAGHQC VQPVNGTVSR
160 170 180 190 200
TKPGSCPPSP LGPVGLALFC QTDIDCEGSM KCCMTIVGYE CTPPQKESDK
210 220 230 240 250
SNKPGECPLA PAITGKALFC RSDNDCDGSE KCCFTKVGKE CVKPIEKPRP
260 270 280 290 300
VAKKGLCPPR PIGPVGLANF CQSDYDCDGS MKCCLTGIGY DCKAPVEEIE
310 320 330 340 350
EVNKTGLCPP TPAITGKALF CRKDNDCDGS EKCCFTEVGK ECVKPIEETK
360 370 380 390 400
PIVKKGSCPP KPNGPVGLAN FCQTDYDCDG SKKCCLTSIG YDCKAPVQES
410 420 430 440 450
EEVQKPGSCP AAPAITGKAL FCRTDKDCDG SEKCCFTKVG KECVQPADEP
460 470 480 490 500
KPIAKKGSCP PAPVGPVGLA SFCQNDYDCD GSKKCCLTSI GYDCKAPVQE
510 520 530 540 550
SEEVQKPGSC PAAPAITGKA LFCRTDKDCD GSEKCCFTKV GKECVQPADE
560 570 580 590 600
PKPIAKKGSC PPAPVGPVGL ASFCQNDYDC DGSKKCCLTS IGYDCKAPVQ
610 620 630 640 650
ESEEVQKPGS CPAAPAITGK ALFCRTDKDC DGSEKCCFTK VGKECVQPAD
660 670 680 690 700
EPKPIAKKGS CPPAPVGPVG LASFCQNDYD CDGSKKCCLT SIGYDCKAPV
710 720 730 740 750
QESEEVQKPG SCPAAPAMTG KALFCRSDND CDGREKCCTT KVGKECVKPV
760 770 780 790 800
RWPGPNAKPG SCPPSPGGAV GLASFCQSDF DCMGYQKCCI TSARYECTNP
810 820 830 840 850
VDENVRPSRR GICPWPYPVR LPVRACSIDD DCEESQKCCP TKAGSACIIP
860 870 880 890 900
VSEEMASGRV SCPPAVYVMF LRDSCRRDED CDDGKKCCDG NGRKSCSVLV

QRS
Length:903
Mass (Da):95,690
Last modified:June 1, 1998 - v1
Checksum:iB55F57DE651ABFB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF036161 mRNA. Translation: AAC04763.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF036161 mRNA. Translation: AAC04763.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiI17.003.
TCDBi1.C.15.1.1. the whipworm stichosome porin (wsp) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di4.10.75.10. 17 hits.
InterProiIPR008197. WAP_dom.
[Graphical view]
PfamiPF00095. WAP. 17 hits.
[Graphical view]
SMARTiSM00217. WAP. 17 hits.
[Graphical view]
SUPFAMiSSF57256. SSF57256. 17 hits.
PROSITEiPS51390. WAP. 17 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The major secreted product of the whipworm, Trichuris, is a pore-forming protein."
    Drake L., Korchev Y., Bashford L., Djamgoz M., Wakelin D., Ashall F., Bundy D.
    Proc. R. Soc. B 257:255-261(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Isolation of a gene family that encodes the porin-like proteins from the human parasitic nematode Trichuris trichiura."
    Barker G.C., Bundy D.A.
    Gene 229:131-136(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO44397_TRITR
AccessioniPrimary (citable) accession number: O44397
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: December 9, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.