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Protein
Submitted name:

AamEcRA2

Gene

AamEcRA2

Organism
Amblyomma americanum (Lone star tick)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorUniRule annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
AamEcRA2Imported
Gene namesi
Name:AamEcRA2Imported
OrganismiAmblyomma americanum (Lone star tick)Imported
Taxonomic identifieri6943 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeAmblyomminaeAmblyomma

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO44338.
SMRiO44338. Positions 183-269, 334-568.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini186 – 26176Nuclear receptor DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation
Contains nuclear receptor DNA-binding domain.SAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR003069. Ecdystd_rcpt.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR01283. ECDYSTEROIDR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O44338-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDDALQLGS GAEQQLDAHL LELAAVALHG LARIFVAAKR DERVALLATH
60 70 80 90 100
DVHTAHRDVE PLEVAADVQR VCRPGQVLQT DDDGGDGGPV PPKRVRQDDA
110 120 130 140 150
GAWISSPSSQ MSVGSLSPPP PLLNGVANSS GLSPVSNCSS YDTYSPRGPC
160 170 180 190 200
KEEMSPSSGG GGLNGYFVDS FGDPKKKKGP APRQQEELCL VCGDRASGYH
210 220 230 240 250
YNALTCEGCK GFFRRSITKN AVYQCKYGNN CDIDMYMRRK CQECRLKKCL
260 270 280 290 300
SVGMRPECVV PEYQCAIKRE SKKHQKDRPN STTRESPSAL MAPSSVGGVS
310 320 330 340 350
PTSQPMGGGG SSLGSSNHEE DKKPVVLSPG VKPLSSSQED LINKLVYYQQ
360 370 380 390 400
EFESPSEEDM KKTTPFPLGD SEEDNQRRFQ HITEITILTV QLIVEFSKRV
410 420 430 440 450
PGFDTLARED QITLLKACSS EVMMLRGARK YDVKTDSIVF ANNQPYTRDN
460 470 480 490 500
YRSASVGDSA DALFRFCRKM CQLRVDNAEY ALLTAIVIFS ERPSLVDPHK
510 520 530 540 550
VERIQEYYIE TLRMYSENHR PPGKNYFARL LSILTELRTL GNMNAEMCFS
560 570
LKVQNKKLPP FLAEIWDIQE
Length:570
Mass (Da):63,128
Last modified:June 1, 1998 - v1
Checksum:i1B0FAF391AA2033F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020188 mRNA. Translation: AAB94567.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020188 mRNA. Translation: AAB94567.1.

3D structure databases

ProteinModelPortaliO44338.
SMRiO44338. Positions 183-269, 334-568.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR003069. Ecdystd_rcpt.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR01283. ECDYSTEROIDR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Isolation of a functional ecdysteroid receptor homologue from the ixodid tick Amblyomma americanum (L.)."
    Guo X., Harmon M.A., Laudet V., Mangelsdorf D.J., Palmer M.J.
    Insect Biochem. Mol. Biol. 27:945-962(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO44338_AMBAM
AccessioniPrimary (citable) accession number: O44338
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: May 11, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.