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Protein
Submitted name:

LeukoTriene A4 Hydrolase homolog

Gene

ltah-1.2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular lipid metabolic process Source: GO_Central
  • negative regulation of fatty acid transport Source: WormBase
  • peptide catabolic process Source: GO_Central
  • proteolysis Source: GO_Central
  • regulation of lipid storage Source: WormBase
  • regulation of peptide transport Source: WormBase

Keywordsi

Molecular functionHydrolaseImported

Enzyme and pathway databases

ReactomeiR-CEL-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)
R-CEL-6798695 Neutrophil degranulation
R-CEL-9018676 Biosynthesis of D-series resolvins
R-CEL-9018681 Biosynthesis of protectins
R-CEL-9018896 Biosynthesis of E-series 18(S)-resolvins
R-CEL-9020265 Biosynthesis of aspirin-triggered D-series resolvins
R-CEL-9023661 Biosynthesis of E-series 18(R)-resolvins

Protein family/group databases

MEROPSiM01.A18

Names & Taxonomyi

Protein namesi
Submitted name:
LeukoTriene A4 Hydrolase homologImported
Gene namesi
Name:ltah-1.2Imported
ORF Names:CELE_ZC416.6Imported, ZC416.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiZC416.6a ; CE28160 ; WBGene00022610 ; ltah-1.2

Subcellular locationi

PTM / Processingi

Proteomic databases

EPDiO44183
PaxDbiO44183
PeptideAtlasiO44183

Expressioni

Gene expression databases

BgeeiWBGene00022610
ExpressionAtlasiO44183 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi6239.ZC416.6.2

Structurei

3D structure databases

ProteinModelPortaliO44183
SMRiO44183
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini469 – 614Leuk-A4-hydro_CInterPro annotationAdd BLAST146

Phylogenomic databases

eggNOGiKOG1047 Eukaryota
COG0308 LUCA
GeneTreeiENSGT00530000063003
HOGENOMiHOG000293296
InParanoidiO44183
KOiK01254
OMAiNFEHFWL
OrthoDBiEOG091G02UX
PhylomeDBiO44183

Family and domain databases

CDDicd09599 M1_LTA4H, 1 hit
Gene3Di1.10.390.10, 1 hit
1.25.40.320, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR038502 M1_LTA-4_hydro/amino_C_sf
IPR034015 M1_LTA4H
IPR001930 Peptidase_M1
IPR015211 Peptidase_M1_C
IPR014782 Peptidase_M1_N
IPR027268 Peptidase_M4/M1_CTD_sf
PANTHERiPTHR11533 PTHR11533, 1 hit
PfamiView protein in Pfam
PF09127 Leuk-A4-hydro_C, 1 hit
PF01433 Peptidase_M1, 1 hit
PRINTSiPR00756 ALADIPTASE
SMARTiView protein in SMART
SM01263 Leuk-A4-hydro_C, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequencei

Sequence statusi: Complete.

O44183-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCQLHNFRPK RDPCSAANIN EITVEHTAIK WTVSFQLKMI IGQATLRCRC
60 70 80 90 100
LTDATKLVLD VRDLSIRSVS INGVDCDFRI APNVYTFFGS KMSVYLPPQF
110 120 130 140 150
QKAGTILQVT VAYGTSPDAT ALQWMKKEQT ADKRMPYLFS QCQAIHARSI
160 170 180 190 200
VPCMDTPSVK STYEAEVTVP TGMTCLMSAI GQGSKGDDDT TTFFYKQPVA
210 220 230 240 250
IPSYLIAIVV GCLEKRDISD RCAVWAEPSV VDKAHWEFAE TEDILASAEE
260 270 280 290 300
IAGKYIWGRY DMVCLPPSFP FGGMENPCLT FLTPTLIAGD RSLVSVIAHE
310 320 330 340 350
IAHSWSGNLV TNSSWEHFWL NEGFTMFIER KICGRLVSED YRQFMAFNGW
360 370 380 390 400
TNSLIPAVYE QFTPTHQFTK LIQDHTNVDP DVAFSCVPYE KGSALLFYLE
410 420 430 440 450
QKLGGSEIFE AYLKDYLKTF AHQAIDSWQW KDHLYKYFAD QKEVLDTVNF
460 470 480 490 500
DLWFNGVGMP PEKPNYGQSM VEACEVLLKK WLAADESTVG DITSEDYYAM
510 520 530 540 550
QPLQQIELLS QLWQHDPPIE HYKLDALNKL YKLNDSQNSE LLLNWLRLCI
560 570 580 590 600
KSKWEECIPK ALDFVNSQGR LKFCRPIYRD LAQWPIANKK ARDVYLKGRS
610 620
QMHPITAEMI AKDLHIRHST HTVCF
Length:625
Mass (Da):71,310
Last modified:October 1, 2001 - v2
Checksum:iF7631F692B6ABB89
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD68240.1
PIRiT32546
RefSeqiNP_500385.1, NM_067984.6
UniGeneiCel.11629

Genome annotation databases

EnsemblMetazoaiZC416.6a; ZC416.6a; WBGene00022610
GeneIDi177123
KEGGicel:CELE_ZC416.6

Similar proteinsi

Entry informationi

Entry nameiO44183_CAEEL
AccessioniPrimary (citable) accession number: O44183
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: October 1, 2001
Last modified: May 23, 2018
This is version 128 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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