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Protein
Submitted name:

Protein-tyrosine-phosphatase

Gene

CELE_M04G7.2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphataseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protein-tyrosine-phosphataseImported
Gene namesi
ORF Names:CELE_M04G7.2Imported, M04G7.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiM04G7.2a; CE17191; WBGene00019773.

PTM / Processingi

Proteomic databases

EPDiO44180.
PaxDbiO44180.
PRIDEiO44180.

Expressioni

Gene expression databases

ExpressionAtlasiO44180. baseline.

Interactioni

Protein-protein interaction databases

DIPiDIP-25589N.
MINTiMINT-1125593.
STRINGi6239.M04G7.2.

Structurei

3D structure databases

ProteinModelPortaliO44180.
SMRiO44180. Positions 226-535.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini266 – 521256Tyrosine-protein phosphataseInterPro annotationAdd
BLAST
Domaini440 – 51273TYR_PHOSPHATASE_2InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0789. Eukaryota.
COG5599. LUCA.
GeneTreeiENSGT00770000120452.
HOGENOMiHOG000019820.
InParanoidiO44180.
OMAiARIITHF.
OrthoDBiEOG754HT7.
PhylomeDBiO44180.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O44180-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMFNRKAKQ EVTKKPEASN GSKNSKSTFV NSKSPNQKRR EVKKSDSDTE
60 70 80 90 100
SSHKNTRRTK PVPVPAASSN SKGSNEKHKR KSVQQVVKKV VNHIPFSPSK
110 120 130 140 150
QPKSTSTPPV SEGNRKRLAM ADVSINQLES EMDSFVKKIE PNERRATQYI
160 170 180 190 200
HSNSLSRSNE AVPPGNVKTS QQKADHHLIR TTRSLIGLDG ETEAVYSKAT
210 220 230 240 250
KASPDKGKLT ADSPSSRRTS KSLEENSSET TNDSISLADD EETREAYRKL
260 270 280 290 300
FKDFAMSSQK MTLDDFKQEF SNLPGDPPSD LCTVFNHPVN NKKNRYSNIP
310 320 330 340 350
CLDISRVQLK FKMPNKNSTD YIHANYIRSP FLKRGYILTQ GPKKETRADF
360 370 380 390 400
WRMIWQENTT AIVMLCQFLE TNREKCAEYF PRNAHCCLQF DKFSVNYEDS
410 420 430 440 450
TVNKSLVTTR LNLSYEGETR LITHWLWKEW PDWQVPESSE VMLKILRKIR
460 470 480 490 500
ARSTPPVIHC SAGVGRSGTL MAVEIALQSI HTHFTLPDIK QIVSHLRVTG
510 520 530 540 550
RAASVQTLQQ YMLIWKVLLD FGVAYKQITE ELAEKFNSTY RRSLRSINGT
Length:550
Mass (Da):62,630
Last modified:June 1, 1998 - v1
Checksum:iC0C47350F967CD64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD73113.1.
PIRiT32543.
RefSeqiNP_499934.1. NM_067533.3.
UniGeneiCel.23813.

Genome annotation databases

EnsemblMetazoaiM04G7.2a; M04G7.2a; WBGene00019773.
GeneIDi187449.
UCSCiM04G7.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD73113.1.
PIRiT32543.
RefSeqiNP_499934.1. NM_067533.3.
UniGeneiCel.23813.

3D structure databases

ProteinModelPortaliO44180.
SMRiO44180. Positions 226-535.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-25589N.
MINTiMINT-1125593.
STRINGi6239.M04G7.2.

Proteomic databases

EPDiO44180.
PaxDbiO44180.
PRIDEiO44180.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiM04G7.2a; M04G7.2a; WBGene00019773.
GeneIDi187449.
UCSCiM04G7.2. c. elegans.

Organism-specific databases

CTDi187449.
WormBaseiM04G7.2a; CE17191; WBGene00019773.

Phylogenomic databases

eggNOGiKOG0789. Eukaryota.
COG5599. LUCA.
GeneTreeiENSGT00770000120452.
HOGENOMiHOG000019820.
InParanoidiO44180.
OMAiARIITHF.
OrthoDBiEOG754HT7.
PhylomeDBiO44180.

Gene expression databases

ExpressionAtlasiO44180. baseline.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO44180_CAEEL
AccessioniPrimary (citable) accession number: O44180
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: June 8, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.