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Protein
Submitted name:

TachyKinin Receptor family

Gene

tkr-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
TachyKinin Receptor familyImported
Gene namesi
Name:tkr-2Imported
ORF Names:C49A9.7Imported, CELE_C49A9.7Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC49A9.7; CE16937; WBGene00016761; tkr-2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei62 – 8726HelicalSequence analysisAdd
BLAST
Transmembranei99 – 11921HelicalSequence analysisAdd
BLAST
Transmembranei139 – 15719HelicalSequence analysisAdd
BLAST
Transmembranei177 – 19620HelicalSequence analysisAdd
BLAST
Transmembranei233 – 25523HelicalSequence analysisAdd
BLAST
Transmembranei282 – 30019HelicalSequence analysisAdd
BLAST
Transmembranei320 – 34425HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiO44148.

Interactioni

Protein-protein interaction databases

STRINGi6239.C49A9.7.

Structurei

3D structure databases

ProteinModelPortaliO44148.
SMRiO44148. Positions 50-364.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini78 – 341264G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4219. Eukaryota.
ENOG410XSC5. LUCA.
GeneTreeiENSGT00760000118781.
HOGENOMiHOG000017800.
InParanoidiO44148.
KOiK04225.
OMAiIVMSIER.
OrthoDBiEOG7N37FW.
PhylomeDBiO44148.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O44148-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTCPLPPSL DEMDLRLAAD KVLNGSLINC TFQSFYDQMY QTHGVYFIFE
60 70 80 90 100
PTPFVHPIVS QIFYGILFTL TIFLALMGNF TVMWIILYHR QMRSVTNYYL
110 120 130 140 150
FNLAVADASI SVFNTGFSWS YNYYYVWKFG SFYCRINNLM GITPICASVF
160 170 180 190 200
TMIVMSIERY YAIIHPLKKR PGRRSTVTII IMIWFMAFLF GVPAFLASKV
210 220 230 240 250
DVYYFYDGYT LYENPLCLAD NYPGGNESLL GQVYNNGLIT VQYILPLCIL
260 270 280 290 300
SAAYYRVGVE LRKDKTVGDV RHAKSVAAKK KASIMLAVVV FIFMIVWFPY
310 320 330 340 350
NAYYLTLHLV EPIGNKMLSL YIYINIYWLG MSSTVFNPVI YYFMNKRFRV
360 370 380 390
GFHHAFRWLP FVRSDKDEYQ TILSQTRPSL MPPTTMAHTD F
Length:391
Mass (Da):45,467
Last modified:June 1, 1998 - v1
Checksum:iD144B695E9AEBDE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD67626.1.
PIRiT32517.
RefSeqiNP_500930.1. NM_068529.1.
UniGeneiCel.13294.

Genome annotation databases

EnsemblMetazoaiC49A9.7; C49A9.7; WBGene00016761.
GeneIDi183595.
KEGGicel:CELE_C49A9.7.
UCSCiC49A9.7. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD67626.1.
PIRiT32517.
RefSeqiNP_500930.1. NM_068529.1.
UniGeneiCel.13294.

3D structure databases

ProteinModelPortaliO44148.
SMRiO44148. Positions 50-364.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C49A9.7.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiO44148.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC49A9.7; C49A9.7; WBGene00016761.
GeneIDi183595.
KEGGicel:CELE_C49A9.7.
UCSCiC49A9.7. c. elegans.

Organism-specific databases

CTDi183595.
WormBaseiC49A9.7; CE16937; WBGene00016761; tkr-2.

Phylogenomic databases

eggNOGiKOG4219. Eukaryota.
ENOG410XSC5. LUCA.
GeneTreeiENSGT00760000118781.
HOGENOMiHOG000017800.
InParanoidiO44148.
KOiK04225.
OMAiIVMSIER.
OrthoDBiEOG7N37FW.
PhylomeDBiO44148.

Miscellaneous databases

NextBioi921688.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO44148_CAEEL
AccessioniPrimary (citable) accession number: O44148
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: March 16, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.