O44055 (O44055_STYLE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: DNA polymerase RuleBase RU000442 EC=2.7.7.7 RuleBase RU000442
Organism	Stylonychia lemnae EMBL AAC38857.1
Taxonomic identifier	5949 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Alveolata › Ciliophora › Intramacronucleata › Spirotrichea › Stichotrichia › Sporadotrichida › Oxytrichidae › Stylonychinae › Stylonychia

Protein attributes

Sequence length	1017 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). RuleBase RU000442
Sequence similarities	Belongs to the DNA polymerase type-B family. RuleBase RU000442

Ontologies

Keywords
Biological process	DNA replication RuleBase RU000442
Ligand	DNA-binding RuleBase RU000442
Molecular function	DNA-directed DNA polymerase RuleBase RU000442 Nucleotidyltransferase Transferase
Gene Ontology (GO)
Biological_process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC38857.1
	Non-terminal residue	1017	1	EMBL AAC38857.1

Sequences

	Sequence		Length	Mass (Da)
	O44055 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 62D369440AF0835D	FASTA	1,017	117,303
	10 20 30 40 50 60 FIVDDDGFGY RDHGGEIWER EDNEEVGGKK KKRKVDVSYL VTLHLYNQII TLNLNFLQPN 70 80 90 100 110 120 ELHITNFMMP ASTIRKNKGG LGNSTITQVK QKPKVTAEQS MDIMNNLLQE LDNKDVDELE 130 140 150 160 170 180 DVNASAVIAE LNKPIAFNKS DELVNKYGVT LETQQDIKAK REYEQTMHEQ TIGQNQQNVN 190 200 210 220 230 240 VFSKKRKLDE ISQPYENRSV GKDQNMSRQS EQLLQQQSIN TSYFDAKSQL SHHNDQSMDY 250 260 270 280 290 300 QSAKDLSMGG GSSESGSAQK SNNVMNVDNT GPMAFSKNQQ NSSASKKDDW AQIKQQNQQA 310 320 330 340 350 360 TSEFKTMEQK SAMDIQEFDL PLNQDGTLSF YWIDAHEENN GADLYIFGKI YQPEIKQFVS 370 380 390 400 410 420 CSMKVNGMQR ELYALPKMQK ISRDLTKEEE SQLVRSVQLE LDDIRKRKKR FQGITKWRCK 430 440 450 460 470 480 AVTRKYAFEM PIQHGEHLFL KIKYDATMTP LPSTVYGNTF ECLFGCNQSM LELFILKRKI 490 500 510 520 530 540 KGPCWMTIKN PKKVKDFKKT WCRQEIEIDN PQFAEVTLDD LNRTDIPPLT SLTFHSKTTR 550 560 570 580 590 600 SQNNTNEIAM ISCLVHNNIN QDGPSTTDKF QTFTLIRKLE GKPMPFDFEQ KLRQKRENIQ 610 620 630 640 650 660 YFTNERQMID LFVTRIFQID PDLIVAHNLC GGIFDLLLAR IQFLKDNHWS RIGRFKKGNI 670 680 690 700 710 720 PTKKFDQGGS NYGGSQWIPR QVTCGRLLVD TFLSAKELVR ETSYDLTYLS KVQLKKDRQD 730 740 750 760 770 780 FDDDLLSQFY LASERIFQLI EHTEKDSYFT FMFMLHLSII PLAKQLTNIA GNLWFRSLQN 790 800 810 820 830 840 ARAERNEMLL LHEFKKKKFI LPDKKPPSAK DFKRGFMEEN EEQDTKGGKK GGKRKKAKYA 850 860 870 880 890 900 GGLVIEPKAG FYDNIVLLLD FNSLYPSIIQ EYNLCFTTVN RRPTKKFDGS DLKNQFKVAD 910 920 930 940 950 960 NEDHQNDDEV EDVELPDKNV NTKDAVLPNV LRDLVQKRRA VKEKMKNEKD PVKLQQLENR 970 980 990 1000 1010 QKAIKLTANS MYGCLGFSSS KFHASAIAAL ITKTGRETLL RTKDIAENKL GFNVVYG

References

[1]	"Phylogenetic relationships among hypotrichous ciliates determined with the macronuclear gene encoding the large, catalytic subunit of DNA polymerase alpha." Hoffman D.C., Prescott D.M. J. Mol. Evol. 45:301-310(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U89703 mRNA. Translation: AAC38857.1.
PIR	T30195.
3D structure databases
ProteinModelPortal	O44055.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.90.1600.10. 2 hits.
InterPro	IPR006172. DNA-dir_DNA_pol_B. IPR006133. DNA-dir_DNA_pol_B_exonuc. IPR006134. DNA-dir_DNA_pol_B_multi_dom. IPR004578. DNA-dir_DNA_pol_B_pol2. IPR024647. DNA_pol_a_cat_su_N. IPR023211. DNA_pol_palm_dom. IPR012337. RNaseH-like_dom. [Graphical view]
Pfam	PF12254. DNA_pol_alpha_N. 1 hit. PF00136. DNA_pol_B. 1 hit. PF03104. DNA_pol_B_exo1. 1 hit. [Graphical view]
PRINTS	PR00106. DNAPOLB.
SMART	SM00486. POLBc. 1 hit. [Graphical view]
SUPFAM	SSF53098. RNaseH_fold. 1 hit.
TIGRFAMs	TIGR00592. pol2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

O44055_STYLE

Accession

Primary (citable) accession number: O44055

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	April 3, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)