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Protein
Submitted name:

Sialidase

Gene
N/A
Organism
Trypanosoma rangeli
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseImported, Hydrolase

Enzyme and pathway databases

BRENDAi3.2.1.18. 8334.

Protein family/group databases

CAZyiGH33. Glycoside Hydrolase Family 33.

Names & Taxonomyi

Protein namesi
Submitted name:
SialidaseImported (EC:3.2.1.18Imported)
OrganismiTrypanosoma rangeliImported
Taxonomic identifieri5698 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaHerpetosoma

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500415860823 – 660Sequence analysisAdd BLAST638

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi419 ↔ 433Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1MZ5X-ray2.20A23-660[»]
1MZ6X-ray2.90A23-660[»]
1N1SX-ray1.64A23-660[»]
1N1TX-ray1.60A23-660[»]
1N1VX-ray2.10A23-660[»]
1N1YX-ray2.80A23-660[»]
1WCSX-ray2.80A20-660[»]
2A75X-ray1.95A23-660[»]
2AGSX-ray1.70A23-660[»]
2FHRX-ray2.20A23-660[»]
ProteinModelPortaliO44049.
SMRiO44049.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO44049.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 376SialidasesInterPro annotationAdd BLAST318

Keywords - Domaini

SignalSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR013320. ConA-like_dom.
IPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiView protein in Pfam
PF13859. BNR_3. 1 hit.
PRINTSiPR01803. TCSIALIDASE.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O44049-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWLAVFVPL FLMACASEPA SALAPGSSRV ELFKRKNSTV PFEESNGTIR
60 70 80 90 100
ERVVHSFRIP TIVNVDGVMV ATADARYETS FDNSFIETAV KYSVDDGATW
110 120 130 140 150
NTQIAIKNSR ASSVSRVMDA TVIVKGNKLY ILVGSFNKTR NSWTQHRDGS
160 170 180 190 200
DWEPLLVVGE VTKSAANGKT TATISWGKPV SLKPLFPAEF DGILTKEFIG
210 220 230 240 250
GVGAAIVGSN GNLVYPVQIA DMGGRVFTKI MYSEDDGNTW KFAEGRSKFG
260 270 280 290 300
CSEPAVLEWE GKLIINNRVD GNRRLVYESS DMGKTWVEAL GTLSHVWTNS
310 320 330 340 350
PTSNQQDCQS SFVAVTIEGK RVMLFTHPLN LKGRWMRDRL HLWMTDNQRI
360 370 380 390 400
FDVGQISIGD ENSGYSSVLY KDDKLYSLHE INTNDVYSLV FVRFIGELQL
410 420 430 440 450
MKSVVRTWKE EDNHLASICT PVVPATPPSK GGCGAAVPTA GLVGFLSHSA
460 470 480 490 500
NGSVWEDVYR CVDANVANAE RVPNGLKFNG VGGGAVWPVA RQGQTRRYQF
510 520 530 540 550
ANYRFTLVAT VTIDELPKGT SPLLGAGLEG PGDAKLLGLS YDKNRQWRPL
560 570 580 590 600
YGAAPASPTG SWELHKKYHV VLTMADRQGS VYVDGQPLAG SGNTVVRGAT
610 620 630 640 650
LPDISHFYIG GPRSKGAPTD SRVTVTNIVL YNRRLNSSEI RTLFLSQDMI
660
GTDGGAGTAA
Length:660
Mass (Da):71,965
Last modified:June 1, 1998 - v1
Checksum:iB5D55765DC4423D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U83180 Genomic DNA. Translation: AAC95493.1.

Similar proteinsi

Entry informationi

Entry nameiO44049_TRYRA
AccessioniPrimary (citable) accession number: O44049
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: August 30, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources