Unreviewed, UniProtKB/TrEMBL O43806 (O43806_HUMAN)

Names and origin

Protein names

Submitted name:
    P27 kip1 protein EMBL CAA59284.1

Gene names

Name:

p27 kip1 EMBL CAA59284.1

Organism

Homo sapiens (Human) EMBL CAA59284.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	158 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	cell cycle arrest Inferred from electronic annotation. Source: InterPro inner ear development Inferred from electronic annotation. Source: Compara negative regulation of cell motion Inferred from electronic annotation. Source: Compara negative regulation of cyclin-dependent protein kinase activity Inferred from electronic annotation. Source: Compara negative regulation of epithelial cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of microtubule polymerization Inferred from electronic annotation. Source: Compara potassium ion transport Inferred from electronic annotation. Source: Compara sensory perception of sound Inferred from electronic annotation. Source: Compara
Cellular component	cytosol Inferred from electronic annotation. Source: Compara nucleus Inferred from direct assay. Source: MGI
Molecular function	cyclin-dependent protein kinase inhibitor activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	158	1	EMBL CAA59284.1

Sequences

	Sequence		Length	Mass (Da)
	O43806-1 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: DB6C2905BA2FD150	FASTA	158	17,651
	10 20 30 40 50 60 MSNVRVSNGS PSLERMDARQ AEHPKPSACR NLFGPVDHEE LTRDLEKHCR DMEEASQRKW 70 80 90 100 110 120 NFDFQNHKPL EGKYEWQEVE KGSLPEFYYR PPRPPKGACK VPAQESQDGS GSRPAAPLIG 130 140 150 APANSEDTHL VDPKTDPSDS QTGLAEQCAG IRKRPATD

References

[1]	"Mutational analysis of the human cyclin-dependent kinase inhibitor p27kip1 in primary breast carcinomas." Ferrando A.A., Balbin M., Pendas A.M., Vizoso F., Velasco G., Lopez-Otin C. Hum. Genet. 97:91-94(1996) [PubMed: 8557269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Breast carcinoma EMBL CAA59284.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X84849 Genomic DNA. Translation: CAA59284.1.
IPI	IPI00006991.
UniGene	Hs.238990
3D structure databases
HSSP	HSSP built from PDB template 1JSU based on UniProtKB P46527.
SMR	O43806. Positions 25-93.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000111276. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:1785. CDKN1B.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	O43806.
Gene expression databases
ArrayExpress	O43806.
Bgee	O43806.
Family and domain databases
InterPro	IPR003175. CDI. IPR015456. Cyclin_inhib_p27. [Graphical view]
PANTHER	PTHR10265. CDI. 1 hit. PTHR10265:SF4. p27_Kip1. 1 hit.
Pfam	PF02234. CDI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O43806_HUMAN

Accession

Primary (citable) accession number: O43806

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	March 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)