Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O43557

- TNF14_HUMAN

UniProt

O43557 - TNF14_HUMAN

Protein

Tumor necrosis factor ligand superfamily member 14

Gene

TNFSF14

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 145 (01 Oct 2014)
      Sequence version 2 (30 Nov 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei82 – 832CleavageSequence Analysis

    GO - Molecular functioni

    1. cysteine-type endopeptidase inhibitor activity involved in apoptotic process Source: UniProtKB
    2. protein binding Source: IntAct
    3. receptor binding Source: UniProtKB

    GO - Biological processi

    1. apoptotic process Source: ProtInc
    2. cellular response to mechanical stimulus Source: UniProtKB
    3. immune response Source: InterPro
    4. negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: GOC
    5. positive regulation of T cell chemotaxis Source: Ensembl
    6. release of cytoplasmic sequestered NF-kappaB Source: UniProtKB
    7. signal transduction Source: UniProtKB
    8. T cell activation Source: UniProtKB
    9. T cell costimulation Source: Ensembl
    10. T cell homeostasis Source: UniProtKB
    11. T cell proliferation Source: UniProtKB

    Keywords - Molecular functioni

    Cytokine

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tumor necrosis factor ligand superfamily member 14
    Alternative name(s):
    Herpes virus entry mediator ligand
    Short name:
    HVEM-L
    Short name:
    Herpesvirus entry mediator ligand
    CD_antigen: CD258
    Cleaved into the following 2 chains:
    Gene namesi
    Name:TNFSF14
    Synonyms:HVEML, LIGHT
    ORF Names:UNQ391/PRO726
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:11930. TNFSF14.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. extracellular space Source: UniProtKB-KW
    3. integral component of membrane Source: UniProtKB-KW
    4. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Cytoplasm, Membrane, Secreted

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA36622.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 240240Tumor necrosis factor ligand superfamily member 14, membrane formPRO_0000034532Add
    BLAST
    Chaini?83 – 240158Tumor necrosis factor ligand superfamily member 14, soluble formPRO_0000034533Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi102 – 1021N-linked (GlcNAc...)1 Publication
    Disulfide bondi154 ↔ 1871 Publication

    Post-translational modificationi

    N-glycosylated.1 Publication
    The soluble form of isoform 1 derives from the membrane form by proteolytic processing.1 Publication

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiO43557.
    PRIDEiO43557.

    Expressioni

    Tissue specificityi

    Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.

    Inductioni

    Up-regulated after T-cell activation.

    Gene expression databases

    BgeeiO43557.
    CleanExiHS_TNFSF14.
    GenevestigatoriO43557.

    Organism-specific databases

    HPAiHPA012700.

    Interactioni

    Subunit structurei

    Homotrimer.

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    TNFRSF14Q929562EBI-524131,EBI-1056653
    TNFRSF6BO954072EBI-524131,EBI-524171

    Protein-protein interaction databases

    BioGridi114277. 8 interactions.
    DIPiDIP-3016N.
    IntActiO43557. 3 interactions.
    STRINGi9606.ENSP00000245912.

    Structurei

    Secondary structure

    1
    240
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi95 – 1028
    Beta strandi107 – 1104
    Beta strandi113 – 1153
    Beta strandi122 – 1298
    Beta strandi132 – 1376
    Beta strandi139 – 15113
    Beta strandi162 – 1698
    Beta strandi173 – 1753
    Beta strandi177 – 1848
    Helixi186 – 1894
    Beta strandi197 – 20913
    Beta strandi214 – 2207
    Helixi222 – 2243
    Beta strandi232 – 2398

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4EN0X-ray2.59A/B/C83-240[»]
    4J6GX-ray2.40A/B83-240[»]
    4KG8X-ray2.25A/B/C83-240[»]
    4KGGX-ray2.78A/B83-240[»]
    4KGQX-ray2.27A/B83-240[»]
    ProteinModelPortaliO43557.
    SMRiO43557. Positions 93-240.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 3737CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini59 – 240182ExtracellularSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei38 – 5821Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tumor necrosis factor family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG40950.
    HOVERGENiHBG061471.
    InParanoidiO43557.
    KOiK05477.
    OMAiAGYYYIY.
    OrthoDBiEOG7V4B0Q.
    PhylomeDBiO43557.
    TreeFamiTF332169.

    Family and domain databases

    Gene3Di2.60.120.40. 1 hit.
    InterProiIPR006053. TNF.
    IPR006052. TNF_dom.
    IPR008983. Tumour_necrosis_fac-like_dom.
    [Graphical view]
    PfamiPF00229. TNF. 1 hit.
    [Graphical view]
    PRINTSiPR01234. TNECROSISFCT.
    SMARTiSM00207. TNF. 1 hit.
    [Graphical view]
    SUPFAMiSSF49842. SSF49842. 1 hit.
    PROSITEiPS50049. TNF_2. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: O43557-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEESVVRPSV FVVDGQTDIP FTRLGRSHRR QSCSVARVGL GLLLLLMGAG    50
    LAVQGWFLLQ LHWRLGEMVT RLPDGPAGSW EQLIQERRSH EVNPAAHLTG 100
    ANSSLTGSGG PLLWETQLGL AFLRGLSYHD GALVVTKAGY YYIYSKVQLG 150
    GVGCPLGLAS TITHGLYKRT PRYPEELELL VSQQSPCGRA TSSSRVWWDS 200
    SFLGGVVHLE AGEKVVVRVL DERLVRLRDG TRSYFGAFMV 240
    Length:240
    Mass (Da):26,350
    Last modified:November 30, 2010 - v2
    Checksum:i49D0B1870F390B39
    GO
    Isoform 2 (identifier: O43557-2) [UniParc]FASTAAdd to Basket

    Also known as: LIGHT delta-TM

    The sequence of this isoform differs from the canonical sequence as follows:
         38-73: Missing.

    Show »
    Length:204
    Mass (Da):22,395
    Checksum:iFF97FD515DB2EB11
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti32 – 321S → L.
    Corresponds to variant rs2291667 [ dbSNP | Ensembl ].
    VAR_027677
    Natural varianti120 – 1201L → V.
    Corresponds to variant rs17851606 [ dbSNP | Ensembl ].
    VAR_027678
    Natural varianti214 – 2141K → E.5 Publications
    Corresponds to variant rs344560 [ dbSNP | Ensembl ].
    VAR_027679

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei38 – 7336Missing in isoform 2. 1 PublicationVSP_006452Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF036581 mRNA. Translation: AAC39563.1.
    AF064090 mRNA. Translation: AAC25169.1.
    AY028261 mRNA. Translation: AAK26160.1.
    AY358812 mRNA. Translation: AAQ89171.1.
    AK292037 mRNA. Translation: BAF84726.1.
    CR541854 mRNA. Translation: CAG46652.1.
    CR541871 mRNA. Translation: CAG46669.1.
    AC008760 Genomic DNA. No translation available.
    CH471139 Genomic DNA. Translation: EAW69072.1.
    CCDSiCCDS12171.1. [O43557-1]
    CCDS45939.1. [O43557-2]
    RefSeqiNP_003798.2. NM_003807.3. [O43557-1]
    NP_742011.2. NM_172014.2. [O43557-2]
    XP_005259727.1. XM_005259670.1. [O43557-2]
    UniGeneiHs.129708.

    Genome annotation databases

    EnsembliENST00000245912; ENSP00000245912; ENSG00000125735. [O43557-2]
    ENST00000599359; ENSP00000469049; ENSG00000125735. [O43557-1]
    GeneIDi8740.
    KEGGihsa:8740.
    UCSCiuc002mfj.2. human. [O43557-2]
    uc002mfk.2. human. [O43557-1]

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF036581 mRNA. Translation: AAC39563.1 .
    AF064090 mRNA. Translation: AAC25169.1 .
    AY028261 mRNA. Translation: AAK26160.1 .
    AY358812 mRNA. Translation: AAQ89171.1 .
    AK292037 mRNA. Translation: BAF84726.1 .
    CR541854 mRNA. Translation: CAG46652.1 .
    CR541871 mRNA. Translation: CAG46669.1 .
    AC008760 Genomic DNA. No translation available.
    CH471139 Genomic DNA. Translation: EAW69072.1 .
    CCDSi CCDS12171.1. [O43557-1 ]
    CCDS45939.1. [O43557-2 ]
    RefSeqi NP_003798.2. NM_003807.3. [O43557-1 ]
    NP_742011.2. NM_172014.2. [O43557-2 ]
    XP_005259727.1. XM_005259670.1. [O43557-2 ]
    UniGenei Hs.129708.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4EN0 X-ray 2.59 A/B/C 83-240 [» ]
    4J6G X-ray 2.40 A/B 83-240 [» ]
    4KG8 X-ray 2.25 A/B/C 83-240 [» ]
    4KGG X-ray 2.78 A/B 83-240 [» ]
    4KGQ X-ray 2.27 A/B 83-240 [» ]
    ProteinModelPortali O43557.
    SMRi O43557. Positions 93-240.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 114277. 8 interactions.
    DIPi DIP-3016N.
    IntActi O43557. 3 interactions.
    STRINGi 9606.ENSP00000245912.

    Proteomic databases

    PaxDbi O43557.
    PRIDEi O43557.

    Protocols and materials databases

    DNASUi 8740.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000245912 ; ENSP00000245912 ; ENSG00000125735 . [O43557-2 ]
    ENST00000599359 ; ENSP00000469049 ; ENSG00000125735 . [O43557-1 ]
    GeneIDi 8740.
    KEGGi hsa:8740.
    UCSCi uc002mfj.2. human. [O43557-2 ]
    uc002mfk.2. human. [O43557-1 ]

    Organism-specific databases

    CTDi 8740.
    GeneCardsi GC19M006663.
    HGNCi HGNC:11930. TNFSF14.
    HPAi HPA012700.
    MIMi 604520. gene.
    neXtProti NX_O43557.
    PharmGKBi PA36622.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG40950.
    HOVERGENi HBG061471.
    InParanoidi O43557.
    KOi K05477.
    OMAi AGYYYIY.
    OrthoDBi EOG7V4B0Q.
    PhylomeDBi O43557.
    TreeFami TF332169.

    Miscellaneous databases

    GeneWikii TNFSF14.
    GenomeRNAii 8740.
    NextBioi 32787.
    PROi O43557.
    SOURCEi Search...

    Gene expression databases

    Bgeei O43557.
    CleanExi HS_TNFSF14.
    Genevestigatori O43557.

    Family and domain databases

    Gene3Di 2.60.120.40. 1 hit.
    InterProi IPR006053. TNF.
    IPR006052. TNF_dom.
    IPR008983. Tumour_necrosis_fac-like_dom.
    [Graphical view ]
    Pfami PF00229. TNF. 1 hit.
    [Graphical view ]
    PRINTSi PR01234. TNECROSISFCT.
    SMARTi SM00207. TNF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49842. SSF49842. 1 hit.
    PROSITEi PS50049. TNF_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator."
      Mauri D.N., Ebner R., Montgomery R.I., Kochel K.D., Cheung T.C., Yu G.-L., Ruben S., Murphy M., Eisenberg R.J., Cohen G.H., Spear P.G., Ware C.F.
      Immunity 8:21-30(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT GLU-214.
    2. "Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth."
      Harrop J.A., McDonnell P.C., Brigham-Burke M., Lyn S.D., Minton J., Tan K.B., Dede K., Spampanato J., Silverman C., Hensley P., DiPrinzio R., Emery J.G., Deen K., Eichman C., Chabot-Fletcher M., Truneh A., Young P.R.
      J. Biol. Chem. 273:27548-27556(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), CHARACTERIZATION.
      Tissue: Liver.
    3. "Genomic characterization of LIGHT reveals linkage to an immune response locus on chromosome 19p13.3 and distinct isoforms generated by alternate splicing or proteolysis."
      Granger S.W., Butrovich K.D., Houshmand P., Edwards W.R., Ware C.F.
      J. Immunol. 167:5122-5128(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), PROTEOLYTIC PROCESSING, VARIANT GLU-214.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT GLU-214.
    5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Spleen.
    6. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT GLU-214.
    7. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT GLU-214.
    9. "Crystal structure of LIGHT."
      New York structural genomics research consortium (NYSGRC)
      Submitted (MAY-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.59 ANGSTROMS) OF 83-240, GLYCOSYLATION AT ASN-102, DISULFIDE BOND.

    Entry informationi

    Entry nameiTNF14_HUMAN
    AccessioniPrimary (citable) accession number: O43557
    Secondary accession number(s): A8K7M2
    , C9J5H4, O75476, Q6FHA1, Q8WVF8, Q96LD2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 21, 2001
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 145 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human cell differentiation molecules
      CD nomenclature of surface proteins of human leucocytes and list of entries
    2. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    3. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    4. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    5. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    6. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    7. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3