UniProtKB - O43392 (O43392_HUMAN)
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Protein
Submitted name:
Aryl hydrocarbon receptor nuclear translocator
Gene
ARNT
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding transcription factor activity Source: InterPro
- protein dimerization activity Source: InterPro
GO - Biological processi
- positive regulation of transcription, DNA-templated Source: MGI
- transcription, DNA-templated Source: UniProtKB-KW
Keywordsi
Molecular function | ReceptorImported |
Biological process | Transcription, Transcription regulationSAAS annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Aryl hydrocarbon receptor nuclear translocatorImported |
Gene namesi | Name:ARNTImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 89 – 142 | BHLHInterPro annotationAdd BLAST | 54 | |
Domaini | 161 – 235 | PASInterPro annotationAdd BLAST | 75 |
Phylogenomic databases
eggNOGi | ENOG410IQ5T. Eukaryota. ENOG410XVHF. LUCA. |
HOGENOMi | HOG000234379. |
HOVERGENi | HBG000164. |
Family and domain databases
CDDi | cd00083. HLH. 1 hit. cd00130. PAS. 1 hit. |
Gene3Di | 4.10.280.10. 1 hit. |
InterProi | View protein in InterPro IPR011598. bHLH_dom. IPR036638. HLH_DNA-bd_sf. IPR001067. Nuc_translocat. IPR000014. PAS. IPR035965. PAS-like_dom_sf. IPR013767. PAS_fold. |
Pfami | View protein in Pfam PF00010. HLH. 1 hit. PF00989. PAS. 1 hit. |
PRINTSi | PR00785. NCTRNSLOCATR. |
SMARTi | View protein in SMART SM00353. HLH. 1 hit. SM00091. PAS. 1 hit. |
SUPFAMi | SSF47459. SSF47459. 1 hit. SSF55785. SSF55785. 3 hits. |
PROSITEi | View protein in PROSITE PS50888. BHLH. 1 hit. PS50112. PAS. 1 hit. |
i Sequence
Sequence statusi: Complete.
O43392-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD
60 70 80 90 100
DDGEGNSKFL RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR
110 120 130 140 150
RRNKMTAYIT ELSDMVPTCS ALARKPDKLT ILRMAVSHMK SLRGTGNTST
160 170 180 190 200
DGSYKPSFLT DQELKHLILE AADGFLFIVS CETGRVVYVS DSVTPVLNQP
210 220 230 240 250
QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK TGTVKKEGQQ
260 270 280 290 300
SSMRMCMGSR RSFICRMRCG SSSVDPVSVN RLSFVRNRCR NGLGSVKDGE
310 320
PHFVVVHCTG YIKAWPPAGV SLPDDDPA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF001307 mRNA. Translation: AAC03365.1. |
UniGenei | Hs.632446. |
Similar proteinsi
Entry informationi
Entry namei | O43392_HUMAN | |
Accessioni | O43392Primary (citable) accession number: O43392 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 1998 |
Last sequence update: | June 1, 1998 | |
Last modified: | March 28, 2018 | |
This is version 120 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |