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Protein
Submitted name:

Aryl hydrocarbon receptor nuclear translocator

Gene

ARNT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingSAAS annotation, ReceptorImported
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Aryl hydrocarbon receptor nuclear translocatorImported
Gene namesi
Name:ARNTImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiO43392.
PeptideAtlasiO43392.

Interactioni

Protein-protein interaction databases

MINTiMINT-7034501.
STRINGi9606.ENSP00000351407.

Structurei

3D structure databases

ProteinModelPortaliO43392.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini89 – 142BHLH (basic helix-loop-helix)InterPro annotationAdd BLAST54
Domaini161 – 235PAS (PER-ARNT-SIM)InterPro annotationAdd BLAST75

Phylogenomic databases

eggNOGiENOG410IQ5T. Eukaryota.
ENOG410XVHF. LUCA.
HOGENOMiHOG000234379.
HOVERGENiHBG000164.

Family and domain databases

CDDicd00130. PAS. 1 hit.
Gene3Di4.10.280.10. 1 hit.
InterProiView protein in InterPro
IPR011598. bHLH_dom.
IPR001067. Nuc_translocat.
IPR000014. PAS.
IPR013767. PAS_fold.
PfamiView protein in Pfam
PF00010. HLH. 1 hit.
PF00989. PAS. 1 hit.
PRINTSiPR00785. NCTRNSLOCATR.
SMARTiView protein in SMART
SM00353. HLH. 1 hit.
SM00091. PAS. 1 hit.
SUPFAMiSSF47459. SSF47459. 1 hit.
SSF55785. SSF55785. 3 hits.
PROSITEiView protein in PROSITE
PS50888. BHLH. 1 hit.
PS50112. PAS. 1 hit.

Sequencei

Sequence statusi: Complete.

O43392-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD
60 70 80 90 100
DDGEGNSKFL RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR
110 120 130 140 150
RRNKMTAYIT ELSDMVPTCS ALARKPDKLT ILRMAVSHMK SLRGTGNTST
160 170 180 190 200
DGSYKPSFLT DQELKHLILE AADGFLFIVS CETGRVVYVS DSVTPVLNQP
210 220 230 240 250
QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK TGTVKKEGQQ
260 270 280 290 300
SSMRMCMGSR RSFICRMRCG SSSVDPVSVN RLSFVRNRCR NGLGSVKDGE
310 320
PHFVVVHCTG YIKAWPPAGV SLPDDDPA
Length:328
Mass (Da):36,012
Last modified:June 1, 1998 - v1
Checksum:i18F056368D984654
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF001307 mRNA. Translation: AAC03365.1.
UniGeneiHs.632446.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF001307 mRNA. Translation: AAC03365.1.
UniGeneiHs.632446.

3D structure databases

ProteinModelPortaliO43392.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-7034501.
STRINGi9606.ENSP00000351407.

Proteomic databases

PaxDbiO43392.
PeptideAtlasiO43392.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IQ5T. Eukaryota.
ENOG410XVHF. LUCA.
HOGENOMiHOG000234379.
HOVERGENiHBG000164.

Miscellaneous databases

ChiTaRSiARNT. human.

Family and domain databases

CDDicd00130. PAS. 1 hit.
Gene3Di4.10.280.10. 1 hit.
InterProiView protein in InterPro
IPR011598. bHLH_dom.
IPR001067. Nuc_translocat.
IPR000014. PAS.
IPR013767. PAS_fold.
PfamiView protein in Pfam
PF00010. HLH. 1 hit.
PF00989. PAS. 1 hit.
PRINTSiPR00785. NCTRNSLOCATR.
SMARTiView protein in SMART
SM00353. HLH. 1 hit.
SM00091. PAS. 1 hit.
SUPFAMiSSF47459. SSF47459. 1 hit.
SSF55785. SSF55785. 3 hits.
PROSITEiView protein in PROSITE
PS50888. BHLH. 1 hit.
PS50112. PAS. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO43392_HUMAN
AccessioniPrimary (citable) accession number: O43392
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: April 12, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.