Unreviewed, UniProtKB/TrEMBL O43392 (O43392_HUMAN)

Names and origin

Protein names

Submitted name:
    Aryl hydrocarbon receptor nuclear translocator EMBL AAC03365.1

Gene names

Name:

ARNT EMBL AAC03365.1

Organism

Homo sapiens (Human) EMBL AAC03365.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 basic helix-loop-helix (bHLH) domain. RuleBase RU000367V1 Spearmint SPM000014 Contains 2 PAS (PER-ARNT-SIM) domains. Spearmint SPM001067

Ontologies

Keywords
Biological process	Transcription Transcription regulation Spearmint SPM000014
Cellular component	Nucleus Spearmint SPM000014
Domain	Repeat Spearmint SPM000014
Ligand	DNA-binding Spearmint SPM000014
Molecular function	Receptor
Gene Ontology (GO)
Biological process	regulation of transcription Inferred from direct assay. Source: MGI
Molecular function	transcription activator activity Inferred from direct assay. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O43392-1 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 18F056368D984654	FASTA	328	36,012
	10 20 30 40 50 60 MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL 70 80 90 100 110 120 RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS 130 140 150 160 170 180 ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS 190 200 210 220 230 240 CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK 250 260 270 280 290 300 TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG SSSVDPVSVN RLSFVRNRCR NGLGSVKDGE 310 320 PHFVVVHCTG YIKAWPPAGV SLPDDDPA

References

[1]	"Aryl hydrocarbon (Ah) nonresponsiveness in estrogen receptor-negative MDA-MB-231 cells is associated with expression of a variant arnt protein." Wilson C.L., Thomsen J., Hoivik D.J., Wormke M.T., Stanker L., Holtzapple C., Safe S.H. Arch. Biochem. Biophys. 346:65-73(1997) [PubMed: 9328285] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF001307 mRNA. Translation: AAC03365.1.
RefSeq	NP_848513.1.
UniGene	Hs.632446
3D structure databases
HSSP	HSSP built from PDB template 1AN4 based on UniProtKB P22415.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000143437. Homo sapiens. [Contig view]
GeneID	405.
Organism-specific databases
HGNC	HGNC:700. ARNT.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	O43392.
Gene expression databases
ArrayExpress	O43392.
Family and domain databases
InterPro	IPR001092. HLH_basic. IPR011598. HLH_DNA_bd. IPR001067. Nuc_translocat. IPR000014. PAS. IPR013767. PAS_fold. [Graphical view]
Gene3D	G3DSA:4.10.280.10. HLH_DNA_bd. 1 hit.
Pfam	PF00010. HLH. 1 hit. PF00989. PAS. 1 hit. [Graphical view]
PRINTS	PR00785. NCTRNSLOCATR.
SMART	SM00353. HLH. 1 hit. SM00091. PAS. 1 hit. [Graphical view]
PROSITE	PS50888. HLH. 1 hit. PS50112. PAS. 1 hit. [Graphical view]
Other Resources
NextBio	1693.

Entry information

Entry name

O43392_HUMAN

Accession

Primary (citable) accession number: O43392

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	November 4, 2008
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)