Reviewed,
UniProtKB/Swiss-Prot O43099 (PMP20_ASPFU)
Last modified
November 25, 2008.
Version 44.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Putative peroxiredoxin pmp20 EC=1.11.1.15 Alternative name(s): Thioredoxin reductase Peroxisomal membrane protein pmp20 Allergen=Asp f 3 | ||||
| Gene names |
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| Organism | Aspergillus fumigatus (Sartorya fumigata) [Complete proteome] | ||||
| Taxonomic identifier | 5085 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus |
Protein attributes
| Sequence length | 168 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH. |
| Subcellular location | PeroxisomePotential. |
| Allergenic properties | Causes an allergic reaction in human. Shares common IgE-binding epitopes with allergen Cand b 2 of Candida boidinii. |
| Sequence similarities | Belongs to the peroxiredoxin 2 family. Contains 1 thioredoxin domain. |
Ontologies
Keywords | |
|---|---|
| Cellular component | Peroxisome |
| Disease | Allergen |
| Domain | Redox-active center |
| Molecular function | Oxidoreductase Peroxidase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | cell redox homeostasis Inferred from electronic annotation. Source: InterPro oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | peroxisome Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | peroxiredoxin activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Allergens of Aspergillus fumigatus and Candida boidinii share IgE-binding epitopes." Hemmann S., Blaser K., Crameri R. Am. J. Respir. Crit. Care Med. 156:1956-1962(1997) [PubMed: 9412580] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: ATCC 42202 / AF-102 / Ag 507. |
| [2] | "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus." Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. Denning D.W.Nature 438:1151-1156(2005) [PubMed: 16372009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Af293 / CBS 101355 / FGSC A1100. |
Cross-references
Sequence databases | |
|---|---|
| U58050 mRNA. Translation: AAB95638.1. AAHF01000012 Genomic DNA. Translation: EAL85811.1. | |
| RefSeq | XP_747849.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1HD2 based on UniProtKB P30044. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3505266. |
| KEGG | afm:AFUA_6G02280. |
Phylogenomic databases | |
| HOGENOM | O43099. |
Family and domain databases | |
| InterPro | IPR013740. Redoxin. IPR012335. Thioredoxin_fold. [Graphical view] |
| Gene3D | G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. |
| Pfam | PF08534. Redoxin. 1 hit. [Graphical view] |
| PROSITE | PS51352. THIOREDOXIN_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PMP20_ASPFU | ||||||||
| Accession | Primary (citable) accession number: O43099 Secondary accession number(s): Q4WCS7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| Allergens Nomenclature of allergens and list of entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with


