SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O43099

- PMP20_ASPFU

UniProt

O43099 - PMP20_ASPFU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Putative peroxiredoxin pmp20
Gene
pmp20, AFUA_6G02280
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.

GO - Molecular functioni

  1. IgE binding Source: ASPGD
  2. peroxidase activity Source: UniProtKB-KW
  3. peroxiredoxin activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative peroxiredoxin pmp20 (EC:1.11.1.15)
Alternative name(s):
Peroxisomal membrane protein pmp20
Thioredoxin reductase
Allergen: Asp f 3
Gene namesi
Name:pmp20
ORF Names:AFUA_6G02280
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000002530: Chromosome 6

Subcellular locationi

Peroxisome Reviewed prediction

GO - Cellular componenti

  1. intracellular Source: ASPGD
  2. peroxisome Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Peroxisome

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Shares common IgE-binding epitopes with allergen Cand b 2 of Candida boidinii.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3121. Asp f 3.0101.
73. Asp f 3.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 168168Putative peroxiredoxin pmp20
PRO_0000056603Add
BLAST

Proteomic databases

PRIDEiO43099.

Interactioni

Protein-protein interaction databases

STRINGi5085.CADAFUAP00000470.

Structurei

3D structure databases

ProteinModelPortaliO43099.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 158155Thioredoxin
Add
BLAST

Sequence similaritiesi

Belongs to the peroxiredoxin 2 family.
Contains 1 thioredoxin domain.

Keywords - Domaini

Redox-active center

Phylogenomic databases

eggNOGiCOG0678.
HOGENOMiHOG000255884.
KOiK14171.
OMAiARHVPEY.
OrthoDBiEOG7X3R3F.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR013740. Redoxin.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF08534. Redoxin. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
PROSITEiPS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O43099-1 [UniParc]FASTAAdd to Basket

« Hide

MSGLKAGDSF PSDVVFSYIP WSEDKGEITA CGIPINYNAS KEWADKKVIL    50
FALPGAFTPV CSARHVPEYI EKLPEIRAKG VDVVAVLAYN DAYVMSAWGK 100
ANQVTGDDIL FLSDPDARFS KSIGWADEEG RTKRYALVID HGKITYAALE 150
PAKNHLEFSS AETVLKHL 168
Length:168
Mass (Da):18,453
Last modified:June 1, 1998 - v1
Checksum:iAFFCD72C5A1CCBB2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U58050 mRNA. Translation: AAB95638.1.
AAHF01000012 Genomic DNA. Translation: EAL85811.1.
RefSeqiXP_747849.1. XM_742756.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00000470; CADAFUAP00000470; CADAFUAG00000470.
GeneIDi3505266.
KEGGiafm:AFUA_6G02280.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U58050 mRNA. Translation: AAB95638.1 .
AAHF01000012 Genomic DNA. Translation: EAL85811.1 .
RefSeqi XP_747849.1. XM_742756.1.

3D structure databases

ProteinModelPortali O43099.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5085.CADAFUAP00000470.

Protein family/group databases

Allergomei 3121. Asp f 3.0101.
73. Asp f 3.

Proteomic databases

PRIDEi O43099.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADAFUAT00000470 ; CADAFUAP00000470 ; CADAFUAG00000470 .
GeneIDi 3505266.
KEGGi afm:AFUA_6G02280.

Phylogenomic databases

eggNOGi COG0678.
HOGENOMi HOG000255884.
KOi K14171.
OMAi ARHVPEY.
OrthoDBi EOG7X3R3F.

Family and domain databases

Gene3Di 3.40.30.10. 1 hit.
InterProi IPR013740. Redoxin.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF08534. Redoxin. 1 hit.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 1 hit.
PROSITEi PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Allergens of Aspergillus fumigatus and Candida boidinii share IgE-binding epitopes."
    Hemmann S., Blaser K., Crameri R.
    Am. J. Respir. Crit. Care Med. 156:1956-1962(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: ATCC 42202 / AF-102 / Ag 507.
  2. "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus."
    Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.
    , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W.
    Nature 438:1151-1156(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.

Entry informationi

Entry nameiPMP20_ASPFU
AccessioniPrimary (citable) accession number: O43099
Secondary accession number(s): Q4WCS7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 1, 1998
Last modified: May 14, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi