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Protein

Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial

Gene

SPBC947.15c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the oxidation of NADH.By similarity

Catalytic activityi

NADH + ubiquinone = NAD+ + ubiquinol.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi92 – 12231FADBy similarityAdd
BLAST
Nucleotide bindingi255 – 29137NADBy similarityAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein, NAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial (EC:1.6.5.9)
Gene namesi
ORF Names:SPBC947.15c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC947.15c.
PomBaseiSPBC947.15c.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial inner membrane Source: PomBase
  • mitochondrion Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3535MitochondrionSequence analysisAdd
BLAST
Chaini36 – 551516Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrialPRO_0000337258Add
BLAST

Proteomic databases

MaxQBiO43090.

Interactioni

Protein-protein interaction databases

BioGridi276744. 13 interactions.
MINTiMINT-4675226.

Structurei

3D structure databases

ProteinModelPortaliO43090.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NADH dehydrogenase family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000182501.
InParanoidiO43090.
KOiK17871.
OMAiKFALHER.
OrthoDBiEOG092C2KAE.
PhylomeDBiO43090.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O43090-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVSKARLQS VVRLSRTVPY SKTMVRSFHV SCAVKNSGNV PTPRNKSFFS
60 70 80 90 100
RALEMAEVTS SLSMLGAVAL FQSLRRLNNS SPKGKSGVPK KNIVVLGSGW
110 120 130 140 150
GAVAAIKNLD PSLYNITLVS PRDHFLFTPM LPSCTVGTLR LPSITEPIVA
160 170 180 190 200
LFKGKIDPSN IHQAECTAID TSAKKVTIRG TTEANEGKEA VIPYDTLVFA
210 220 230 240 250
IGAGNQTFGI QGVRDHGCFL KEAGDAKKVF NRIFEILEQV RFNKDLSPEE
260 270 280 290 300
RARLLHITVV GGGPTGMEFA AEMQDFIDND VKDMFPELQK DIHVTLIEAA
310 320 330 340 350
PGVLPMFTKS LITYTENLFK NLNIKIMTKT VVKDVNEKNL IVQKTNPDGS
360 370 380 390 400
KAMQEIPYGM LVWAAGITAR PLTRTLMSSI PEQSGARKGL IVDEFFRVKG
410 420 430 440 450
VPEMYAVGDC AFSGLPATAQ VANQQGAWLA KNLNVEGKKF ALHERIQALE
460 470 480 490 500
KQLGEKEAPS QVAGLKQQVE QLKLEPFKYH HQGALAYVGD EKAIADLKLP
510 520 530 540 550
FMKKMLPLQG IVGHTFWRLA YLNELISARS QFMVLIDWLK TRLFGRYDAK

V
Length:551
Mass (Da):60,781
Last modified:June 1, 1998 - v1
Checksum:iC8CE3C56F88108AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA17043.1.
PIRiT40767.
RefSeqiNP_595261.1. NM_001021168.2.

Genome annotation databases

EnsemblFungiiSPBC947.15c.1; SPBC947.15c.1:pep; SPBC947.15c.
GeneIDi2540211.
KEGGispo:SPBC947.15c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA17043.1.
PIRiT40767.
RefSeqiNP_595261.1. NM_001021168.2.

3D structure databases

ProteinModelPortaliO43090.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276744. 13 interactions.
MINTiMINT-4675226.

Proteomic databases

MaxQBiO43090.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC947.15c.1; SPBC947.15c.1:pep; SPBC947.15c.
GeneIDi2540211.
KEGGispo:SPBC947.15c.

Organism-specific databases

EuPathDBiFungiDB:SPBC947.15c.
PomBaseiSPBC947.15c.

Phylogenomic databases

HOGENOMiHOG000182501.
InParanoidiO43090.
KOiK17871.
OMAiKFALHER.
OrthoDBiEOG092C2KAE.
PhylomeDBiO43090.

Miscellaneous databases

PROiO43090.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiNDH2_SCHPO
AccessioniPrimary (citable) accession number: O43090
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 1, 1998
Last modified: September 7, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.