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Protein

ATPase-like fidgetin

Gene

alf1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi419 – 4268ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATPase-like fidgetin
Alternative name(s):
Protein sur2
Gene namesi
Name:alf1
Synonyms:sur2
ORF Names:SPBC947.01
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC947.01.
PomBaseiSPBC947.01.

Subcellular locationi

GO - Cellular componenti

  • cell division site Source: PomBase
  • cell tip Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 660660ATPase-like fidgetinPRO_0000290650Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei177 – 1771Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO43078.

PTM databases

iPTMnetiO43078.
SwissPalmiO43078.

Interactioni

Protein-protein interaction databases

BioGridi277763. 43 interactions.
MINTiMINT-4675138.

Structurei

3D structure databases

ProteinModelPortaliO43078.
SMRiO43078. Positions 365-653.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi145 – 344200Ser-richAdd
BLAST

Sequence similaritiesi

Belongs to the AAA ATPase family.Curated

Phylogenomic databases

InParanoidiO43078.
OrthoDBiEOG72JWRT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
IPR015415. Vps4_C.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF09336. Vps4_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00674. AAA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O43078-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSDLDRILP IASRALLCEG NRDWAGAYVS YCKVLEEMKK SSAARDRMGL
60 70 80 90 100
GPLTGAEACS WNGLYDNCLS KASKLRKTIL ESEMERQNYQ LAAKLSKKAP
110 120 130 140 150
VDLHPLRPVR SQTPAYTPMT TRMMYRQTRG AQSEVNLSTP KQIYSKHSPP
160 170 180 190 200
STSTSSIVSS SYGDAPSYLA PSKPNRSPPL KPEDPFASFN SSASAIAAAS
210 220 230 240 250
KSAAASASAL SSDTGRSATM NSTTFPTAMK SQSTTKPTLS NSVSSPSIQV
260 270 280 290 300
SNNQNANNST PLSFHAPIPP LHVPAVPLTS ASHSSSDGKS RKHPSPYKPY
310 320 330 340 350
LNSSHDTLGS STRPSSADTA GSPATSPPAT ADSKTIVSKT ISASTTQQTE
360 370 380 390 400
PLQQTTPSSD FEYAIMNEII SNHEPVYWSD IAGLDDAKNS LKEAVIYPFL
410 420 430 440 450
RPELFQGLRE PVQGMLLFGP PGTGKTMLAR AVATEAKATF FSISASSLTS
460 470 480 490 500
KYLGDSEKLV RALFEVAKRQ TCSVIFVDEI DSILSARNDS GNEHESSRRL
510 520 530 540 550
KTEFLIQWSS LTNAAPDKQT GHSPRVLVLA ATNLPWCIDE AARRRFVKRT
560 570 580 590 600
YIPLPEKETR YKHLSHLLHN QVHCLTEEDL EELVNLTEGY SGSDITALAK
610 620 630 640 650
DAAMGPLRNL GDALLTTSAE MIPPISLNHF KASLRTIRPS VSQEGIHRYE
660
EWNKQFGSQR
Length:660
Mass (Da):71,733
Last modified:June 1, 1998 - v1
Checksum:i908080909AC2826C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA17029.1.
PIRiT40781.
RefSeqiNP_595275.1. NM_001021182.2.

Genome annotation databases

EnsemblFungiiSPBC947.01.1; SPBC947.01.1:pep; SPBC947.01.
GeneIDi2541249.
KEGGispo:SPBC947.01.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA17029.1.
PIRiT40781.
RefSeqiNP_595275.1. NM_001021182.2.

3D structure databases

ProteinModelPortaliO43078.
SMRiO43078. Positions 365-653.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277763. 43 interactions.
MINTiMINT-4675138.

PTM databases

iPTMnetiO43078.
SwissPalmiO43078.

Proteomic databases

MaxQBiO43078.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC947.01.1; SPBC947.01.1:pep; SPBC947.01.
GeneIDi2541249.
KEGGispo:SPBC947.01.

Organism-specific databases

EuPathDBiFungiDB:SPBC947.01.
PomBaseiSPBC947.01.

Phylogenomic databases

InParanoidiO43078.
OrthoDBiEOG72JWRT.

Miscellaneous databases

PROiO43078.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
IPR015415. Vps4_C.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF09336. Vps4_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00674. AAA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiALF1_SCHPO
AccessioniPrimary (citable) accession number: O43078
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: June 1, 1998
Last modified: June 8, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.