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Protein

Putative transcription factor sre2

Gene

sre2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Putative transcription factor.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transcription factor sre2
Alternative name(s):
Sterol regulatory element-binding protein 2
Gene namesi
Name:sre2
ORF Names:SPBC354.05c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC354.05c
PomBaseiSPBC354.05c sre2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei719 – 739HelicalSequence analysisAdd BLAST21
Transmembranei748 – 768HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cytoplasm, Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003562421 – 793Putative transcription factor sre2Add BLAST793

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei344Phosphoserine1 Publication1
Modified residuei345Phosphoserine1 Publication1
Modified residuei355Phosphoserine1 Publication1
Modified residuei356Phosphotyrosine1 Publication1

Post-translational modificationi

May undergo proteolytic cleavage to release the soluble transcription factor from the membrane.

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO43019
PaxDbiO43019
PRIDEiO43019

PTM databases

iPTMnetiO43019

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi277559, 209 interactors
STRINGi4896.SPBC354.05c.1

Structurei

3D structure databases

ProteinModelPortaliO43019
SMRiO43019
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini426 – 495bHLHPROSITE-ProRule annotationAdd BLAST70

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi344 – 400Ser-richAdd BLAST57

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiO43019
OrthoDBiEOG092C0ASF

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequencei

Sequence statusi: Complete.

O43019-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCPSQHSSLK DIHRQLENTA ISNPTENADP SSYVDGSNIM DFKHPSIVSS
60 70 80 90 100
SASSSYPISH VPSVGTRGIP RSYSMASAYP YQVNSNSMDA STAFNLNQDV
110 120 130 140 150
ADKPMLARNS IDSSINTELG PLESNHWFTQ AQDHSRQYSS SWDPSIDPFE
160 170 180 190 200
VKNSLHDSTD LSITHHPHLP INHQGNTWKH ANESLQSNQG PVPNTKFVGL
210 220 230 240 250
ETTQTDSYQQ SSVNSVVKIE EADATYALRE ESGQFNTFTG AENPSISPHS
260 270 280 290 300
LNPNFPQYTE KPALTLLQSP KQNSNYDTSN FQNSVSDSSM QFTNEGMPSP
310 320 330 340 350
VKGIMSSDDA VAFNFSQYST VYPQNAPENG NEFETPNKLK RTVSSPCASI
360 370 380 390 400
SSKRSYGDIA QDCSYISSKT NGGGPSDSPS SSSTSVRGSV NDSNSPISSS
410 420 430 440 450
ATFAIQSNGV EPVGLSTQEQ NLSPLSKRSA HNMIEKRYRS NLNDKIAELR
460 470 480 490 500
DAVPTLRSGY NSTTADELKG TYVPLSRKLN KATILSKATE YIKSLQSKNK
510 520 530 540 550
KLIEENKILQ KRLSEYTSVI QASLTAPSQP ASLSLLGPPG NTPGHRNVPP
560 570 580 590 600
ILKRSSIGTP SQQAYFPDAP HNCHSVPQNS SYPRPPMQVN RSPIDSMQTI
610 620 630 640 650
PHANFNEMHN AYSSRYPLKY SKSCNAVSHT SMMHPQEYGG SLPSSTVPSD
660 670 680 690 700
YNQPQLVSPR AQADQQGLSY KNVGRAVLNG LVGLETVHML TNPDDAGSSN
710 720 730 740 750
RFSMSVLPIS PSLHSILRFL LLLLAFLCFA MHILLTPEAT LRKWASSIYL
760 770 780 790
SFRLECVFIS FLIFSVPIYD WGNYLNLRGK LLSELNLESG VAT
Length:793
Mass (Da):86,834
Last modified:June 1, 1998 - v1
Checksum:iB9A4E0BBFA79C3A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA17805.1
PIRiT40285
RefSeqiNP_595229.1, NM_001021135.2

Genome annotation databases

EnsemblFungiiSPBC354.05c.1; SPBC354.05c.1:pep; SPBC354.05c
GeneIDi2541044
KEGGispo:SPBC354.05c

Entry informationi

Entry nameiSRE2_SCHPO
AccessioniPrimary (citable) accession number: O43019
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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