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Protein

Set1 complex component swd3

Gene

swd3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

The Set1 complex specifically methylates 'Lys-4' of histone H3.1 Publication

GO - Biological processi

  • heterochromatin assembly involved in chromatin silencing Source: PomBase
  • histone H3-K4 methylation Source: PomBase

Enzyme and pathway databases

ReactomeiR-SPO-8951664 Neddylation

Names & Taxonomyi

Protein namesi
Recommended name:
Set1 complex component swd3
Short name:
Set1C component swd3
Alternative name(s):
COMPASS component swd3
Complex proteins associated with set1 protein swd3
Gene namesi
Name:swd3Imported
ORF Names:SPBC354.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC354.03
PomBaseiSPBC354.03 swd3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000512541 – 380Set1 complex component swd3Add BLAST380

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei379Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO43017
PaxDbiO43017
PRIDEiO43017

PTM databases

iPTMnetiO43017

Interactioni

Subunit structurei

Component of the Set1 complex composed of ash2, sdc1, set1, shg1, spp1, swd1, swd2 and swd3.2 Publications

Protein-protein interaction databases

BioGridi277445, 232 interactors
STRINGi4896.SPBC354.03.1

Structurei

3D structure databases

ProteinModelPortaliO43017
SMRiO43017
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati52 – 91WD 1Sequence analysisAdd BLAST40
Repeati94 – 133WD 2Sequence analysisAdd BLAST40
Repeati136 – 177WD 3Sequence analysisAdd BLAST42
Repeati179 – 219WD 4Sequence analysisAdd BLAST41
Repeati221 – 262WD 5Sequence analysisAdd BLAST42
Repeati291 – 330WD 6Sequence analysisAdd BLAST40
Repeati335 – 374WD 7Sequence analysisAdd BLAST40

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

InParanoidiO43017
KOiK14963
OrthoDBiEOG092C172M
PhylomeDBiO43017

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR037866 Swd3-like
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR22847:SF603 PTHR22847:SF603, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 4 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 6 hits
SUPFAMiSSF50978 SSF50978, 2 hits
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 3 hits
PS50082 WD_REPEATS_2, 5 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

O43017-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSTAQQFPL NHDLQVQKDQ KGVVEEDEEQ IHKRIRNYES HSGFSEYCTL
60 70 80 90 100
FGHEKSVTCV SVSPNKRWIA TSSSDGTIKI WSALTFRLEC TLFGHYRGIS
110 120 130 140 150
QVKWATGSKY LASASDDKTI RIWDFEKRCS VRCLKGHTNY VSSIDFNPLG
160 170 180 190 200
TLLVSGSWDE TVRIWNLQDG TCLRMLPAHS EPIISVSISA DGTLCATASY
210 220 230 240 250
DGMARIWDVL SGQCLKTLVE PINVPLSNLQ FTENRKYLLV SNLNSQIRLW
260 270 280 290 300
DYRRNRVVRI FDSHVNTRYS MSWDCYSSKN IPKNTEALPN NDSSYPDDAE
310 320 330 340 350
SFMHDAYLLI PSEDGTIQIT DPSTKIIIDD SIRHSDDPET SLLNVTSLGP
360 370 380
FIITSGTDPY VRVWAPSLLL SKHEKDGFSP
Length:380
Mass (Da):42,980
Last modified:June 1, 1998 - v1
Checksum:iB5A962506B0C0D7A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA17803.1
PIRiT40283
RefSeqiNP_595227.1, NM_001021133.2

Genome annotation databases

EnsemblFungiiSPBC354.03.1; SPBC354.03.1:pep; SPBC354.03
GeneIDi2540929
KEGGispo:SPBC354.03

Similar proteinsi

Entry informationi

Entry nameiSWD3_SCHPO
AccessioniPrimary (citable) accession number: O43017
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health