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Protein

Set1 complex component swd3

Gene

swd3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

The Set1 complex specifically methylates 'Lys-4' of histone H3.1 Publication

GO - Biological processi

  • heterochromatin assembly involved in chromatin silencing Source: PomBase
  • histone H3-K4 methylation Source: PomBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Set1 complex component swd3
Short name:
Set1C component swd3
Alternative name(s):
COMPASS component swd3
Complex proteins associated with set1 protein swd3
Gene namesi
Name:swd3Imported
ORF Names:SPBC354.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC354.03.
PomBaseiSPBC354.03. swd3.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleus Source: PomBase
  • Set1C/COMPASS complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000512541 – 380Set1 complex component swd3Add BLAST380

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei379Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO43017.
PRIDEiO43017.

PTM databases

iPTMnetiO43017.

Interactioni

Subunit structurei

Component of the Set1 complex composed of ash2, sdc1, set1, shg1, spp1, swd1, swd2 and swd3.2 Publications

Protein-protein interaction databases

BioGridi277445. 231 interactors.
MINTiMINT-4674657.

Structurei

3D structure databases

ProteinModelPortaliO43017.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati52 – 91WD 1Sequence analysisAdd BLAST40
Repeati94 – 133WD 2Sequence analysisAdd BLAST40
Repeati136 – 177WD 3Sequence analysisAdd BLAST42
Repeati179 – 219WD 4Sequence analysisAdd BLAST41
Repeati221 – 262WD 5Sequence analysisAdd BLAST42
Repeati291 – 330WD 6Sequence analysisAdd BLAST40
Repeati335 – 374WD 7Sequence analysisAdd BLAST40

Sequence similaritiesi

Contains 7 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

InParanoidiO43017.
KOiK14963.
OrthoDBiEOG092C172M.
PhylomeDBiO43017.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 4 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 6 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O43017-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSTAQQFPL NHDLQVQKDQ KGVVEEDEEQ IHKRIRNYES HSGFSEYCTL
60 70 80 90 100
FGHEKSVTCV SVSPNKRWIA TSSSDGTIKI WSALTFRLEC TLFGHYRGIS
110 120 130 140 150
QVKWATGSKY LASASDDKTI RIWDFEKRCS VRCLKGHTNY VSSIDFNPLG
160 170 180 190 200
TLLVSGSWDE TVRIWNLQDG TCLRMLPAHS EPIISVSISA DGTLCATASY
210 220 230 240 250
DGMARIWDVL SGQCLKTLVE PINVPLSNLQ FTENRKYLLV SNLNSQIRLW
260 270 280 290 300
DYRRNRVVRI FDSHVNTRYS MSWDCYSSKN IPKNTEALPN NDSSYPDDAE
310 320 330 340 350
SFMHDAYLLI PSEDGTIQIT DPSTKIIIDD SIRHSDDPET SLLNVTSLGP
360 370 380
FIITSGTDPY VRVWAPSLLL SKHEKDGFSP
Length:380
Mass (Da):42,980
Last modified:June 1, 1998 - v1
Checksum:iB5A962506B0C0D7A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA17803.1.
PIRiT40283.
RefSeqiNP_595227.1. NM_001021133.2.

Genome annotation databases

EnsemblFungiiSPBC354.03.1; SPBC354.03.1:pep; SPBC354.03.
GeneIDi2540929.
KEGGispo:SPBC354.03.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA17803.1.
PIRiT40283.
RefSeqiNP_595227.1. NM_001021133.2.

3D structure databases

ProteinModelPortaliO43017.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277445. 231 interactors.
MINTiMINT-4674657.

PTM databases

iPTMnetiO43017.

Proteomic databases

MaxQBiO43017.
PRIDEiO43017.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC354.03.1; SPBC354.03.1:pep; SPBC354.03.
GeneIDi2540929.
KEGGispo:SPBC354.03.

Organism-specific databases

EuPathDBiFungiDB:SPBC354.03.
PomBaseiSPBC354.03. swd3.

Phylogenomic databases

InParanoidiO43017.
KOiK14963.
OrthoDBiEOG092C172M.
PhylomeDBiO43017.

Miscellaneous databases

PROiO43017.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 4 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 6 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSWD3_SCHPO
AccessioniPrimary (citable) accession number: O43017
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: June 1, 1998
Last modified: November 30, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.