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Protein

U6 snRNA-associated Sm-like protein LSm5

Gene

lsm5

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. LSm5 is required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

mRNA processing, mRNA splicing, rRNA processing, tRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

ReactomeiR-SPO-430039. mRNA decay by 5' to 3' exoribonuclease.

Names & Taxonomyi

Protein namesi
Recommended name:
U6 snRNA-associated Sm-like protein LSm5
Gene namesi
Name:lsm5
ORF Names:SPBC20F10.09
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC20F10.09.
PomBaseiSPBC20F10.09. lsm5.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8080U6 snRNA-associated Sm-like protein LSm5PRO_0000317307Add
BLAST

Proteomic databases

MaxQBiO42978.

Interactioni

Subunit structurei

LSm subunits form a heteromer with a doughnut shape.By similarity

Protein-protein interaction databases

BioGridi277246. 8 interactions.
MINTiMINT-4674402.

Structurei

Secondary structure

1
80
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 137Combined sources
Turni14 – 163Combined sources
Beta strandi17 – 3620Combined sources
Beta strandi42 – 5110Combined sources
Turni52 – 543Combined sources
Beta strandi57 – 659Combined sources
Beta strandi70 – 756Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3SWNX-ray2.50A/D/P/S1-80[»]
4EMKX-ray2.30A1-80[»]
ProteinModelPortaliO42978.
SMRiO42978. Positions 5-79.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO42978.

Family & Domainsi

Sequence similaritiesi

Belongs to the snRNP Sm proteins family.Curated

Phylogenomic databases

HOGENOMiHOG000223547.
InParanoidiO42978.
KOiK12624.
OMAiSRIWIAM.
OrthoDBiEOG092C5VL3.
PhylomeDBiO42978.

Family and domain databases

InterProiIPR010920. LSM_dom.
IPR001163. LSM_dom_euk/arc.
[Graphical view]
PfamiPF01423. LSM. 1 hit.
[Graphical view]
SMARTiSM00651. Sm. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.

Sequencei

Sequence statusi: Complete.

O42978-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMTILPLEL IDKCIGSNLW VIMKSEREFA GTLVGFDDYV NIVLKDVTEY
60 70 80
DTVTGVTEKH SEMLLNGNGM CMLIPGGKPE
Length:80
Mass (Da):8,853
Last modified:May 1, 1999 - v2
Checksum:i8F9576156A97F54C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA16849.2.
PIRiT39880.
RefSeqiNP_596373.1. NM_001022294.2.

Genome annotation databases

EnsemblFungiiSPBC20F10.09.1; SPBC20F10.09.1:pep; SPBC20F10.09.
GeneIDi2540723.
KEGGispo:SPBC20F10.09.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA16849.2.
PIRiT39880.
RefSeqiNP_596373.1. NM_001022294.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3SWNX-ray2.50A/D/P/S1-80[»]
4EMKX-ray2.30A1-80[»]
ProteinModelPortaliO42978.
SMRiO42978. Positions 5-79.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277246. 8 interactions.
MINTiMINT-4674402.

Proteomic databases

MaxQBiO42978.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC20F10.09.1; SPBC20F10.09.1:pep; SPBC20F10.09.
GeneIDi2540723.
KEGGispo:SPBC20F10.09.

Organism-specific databases

EuPathDBiFungiDB:SPBC20F10.09.
PomBaseiSPBC20F10.09. lsm5.

Phylogenomic databases

HOGENOMiHOG000223547.
InParanoidiO42978.
KOiK12624.
OMAiSRIWIAM.
OrthoDBiEOG092C5VL3.
PhylomeDBiO42978.

Enzyme and pathway databases

ReactomeiR-SPO-430039. mRNA decay by 5' to 3' exoribonuclease.

Miscellaneous databases

EvolutionaryTraceiO42978.
PROiO42978.

Family and domain databases

InterProiIPR010920. LSM_dom.
IPR001163. LSM_dom_euk/arc.
[Graphical view]
PfamiPF01423. LSM. 1 hit.
[Graphical view]
SMARTiSM00651. Sm. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiLSM5_SCHPO
AccessioniPrimary (citable) accession number: O42978
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 1, 1999
Last modified: September 7, 2016
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.